Chromatography, Ion Exchange
"Chromatography, Ion Exchange" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Separation technique in which the stationary phase consists of ion exchange resins. The resins contain loosely held small ions that easily exchange places with other small ions of like charge present in solutions washed over the resins.
| Descriptor ID |
D002852
|
| MeSH Number(s) |
E05.196.181.400.383
|
| Concept/Terms |
Chromatography, Ion Exchange- Chromatography, Ion Exchange
- Chromatographies, Ion Exchange
- Ion Exchange Chromatographies
- Chromatography, Ion-Exchange
- Chromatographies, Ion-Exchange
- Ion-Exchange Chromatographies
- Ion-Exchange Chromatography
- Ion Exchange Chromatography
|
Below are MeSH descriptors whose meaning is more general than "Chromatography, Ion Exchange".
Below are MeSH descriptors whose meaning is more specific than "Chromatography, Ion Exchange".
This graph shows the total number of publications written about "Chromatography, Ion Exchange" by people in this website by year, and whether "Chromatography, Ion Exchange" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 4 | 6 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 4 | 0 | 4 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chromatography, Ion Exchange" by people in Profiles.
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Welsh JP, Altern SH, Lyall JY, Burgess S, Rauscher MA, Lenhoff AM, Cramer SM, Williams C. Coupling high-throughput and modeling approaches to streamline early-stage process development for biologics. Biotechnol Prog. 2025 May-Jun; 41(3):e3523.
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Bhoyar S, Kumar V, Foster M, Xu X, Traylor SJ, Guo J, Lenhoff AM. Predictive mechanistic modeling of loading and elution in protein A chromatography. J Chromatogr A. 2024 Jan 04; 1713:464558.
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Altern SH, Welsh JP, Lyall JY, Kocot AJ, Burgess S, Kumar V, Williams C, Lenhoff AM, Cramer SM. Isotherm model discrimination for multimodal chromatography using mechanistic models derived from high-throughput batch isotherm data. J Chromatogr A. 2023 Mar 29; 1693:463878.
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Herman CE, Xu X, Traylor SJ, Ghose S, Li ZJ, Lenhoff AM. Behavior of weakly adsorbing protein impurities in flow-through ion-exchange chromatography. J Chromatogr A. 2022 Feb 08; 1664:462788.
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Kumar V, Leweke S, Heymann W, von Lieres E, Schlegel F, Westerberg K, Lenhoff AM. Robust mechanistic modeling of protein ion-exchange chromatography. J Chromatogr A. 2021 Dec 20; 1660:462669.
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Khanal O, Kumar V, Lenhoff AM. Displacement to separate host-cell proteins and aggregates in cation-exchange chromatography of monoclonal antibodies. Biotechnol Bioeng. 2021 01; 118(1):164-174.
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Kumar V, Lenhoff AM. Mechanistic Modeling of Preparative Column Chromatography for Biotherapeutics. Annu Rev Chem Biomol Eng. 2020 06 07; 11:235-255.
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Khanal O, Kumar V, Westerberg K, Schlegel F, Lenhoff AM. Multi-column displacement chromatography for separation of charge variants of monoclonal antibodies. J Chromatogr A. 2019 Feb 08; 1586:40-51.
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Bhambure R, Angelo JM, Gillespie CM, Phillips M, Graalfs H, Lenhoff AM. Ionic strength-dependent changes in tentacular ion exchangers with variable ligand density. II. Functional properties. J Chromatogr A. 2017 Jul 14; 1506:55-64.
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Angelo JM, Lenhoff AM. Determinants of protein elution rates from preparative ion-exchange adsorbents. J Chromatogr A. 2016 Apr 01; 1440:94-104.