Corticotropin-Releasing Hormone
"Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
| Descriptor ID |
D003346
|
| MeSH Number(s) |
D06.472.699.327.740.140 D12.644.400.400.740.140 D12.644.548.365.740.140 D12.776.631.650.405.740.140
|
| Concept/Terms |
Corticotropin-Releasing Hormone- Corticotropin-Releasing Hormone
- Corticotropin Releasing Hormone
- Corticoliberin
- Corticotropin-Releasing Factor
- Corticotropin Releasing Factor
- Corticotropin-Releasing Factor-41
- Corticotropin Releasing Factor 41
- CRF (ACTH)
- Corticotropin-Releasing Hormone-41
- Corticotropin Releasing Hormone 41
- CRF-41
- ACTH-Releasing Hormone
- ACTH Releasing Hormone
- ACTH-Releasing Factor
- ACTH Releasing Factor
|
Below are MeSH descriptors whose meaning is more general than "Corticotropin-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Corticotropin-Releasing Hormone".
This graph shows the total number of publications written about "Corticotropin-Releasing Hormone" by people in this website by year, and whether "Corticotropin-Releasing Hormone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 2 | 3 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Corticotropin-Releasing Hormone" by people in Profiles.
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Amin M, Horst N, Wu R, Gragnoli C. Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome. J Ovarian Res. 2023 Aug 05; 16(1):155.
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Ross JA, Alexis R, Reyes BAS, Risbrough V, Van Bockstaele EJ. Localization of amyloid beta peptides to locus coeruleus and medial prefrontal cortex in corticotropin releasing factor overexpressing male and female mice. Brain Struct Funct. 2019 Sep; 224(7):2385-2405.
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Serova LI, Nwokafor C, Van Bockstaele EJ, Reyes BAS, Lin X, Sabban EL. Single prolonged stress PTSD model triggers progressive severity of anxiety, altered gene expression in locus coeruleus and hypothalamus and effected sensitivity to NPY. Eur Neuropsychopharmacol. 2019 04; 29(4):482-492.
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Enman NM, Reyes BAS, Shi Y, Valentino RJ, Van Bockstaele EJ. Sex differences in morphine-induced trafficking of mu-opioid and corticotropin-releasing factor receptors in locus coeruleus neurons. Brain Res. 2019 03 01; 1706:75-85.
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Wyrofsky RR, Reyes BAS, Yu D, Kirby LG, Van Bockstaele EJ. Sex differences in the effect of cannabinoid type 1 receptor deletion on locus coeruleus-norepinephrine neurons and corticotropin releasing factor-mediated responses. Eur J Neurosci. 2018 09; 48(5):2118-2138.
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Theisen CC, Reyes BAS, Sabban EL, Van Bockstaele EJ. Ultrastructural Characterization of Corticotropin-Releasing Factor and Neuropeptide Y in the Rat Locus Coeruleus: Anatomical Evidence for Putative Interactions. Neuroscience. 2018 08 01; 384:21-40.
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R Wyrofsky R, Reyes BAS, Van Bockstaele EJ. Co-localization of the cannabinoid type 1 receptor with corticotropin-releasing factor-containing afferents in the noradrenergic nucleus locus coeruleus: implications for the cognitive limb of the stress response. Brain Struct Funct. 2017 Sep; 222(7):3007-3023.
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Reyes BA, Zitnik G, Foster C, Van Bockstaele EJ, Valentino RJ. Social Stress Engages Neurochemically-Distinct Afferents to the Rat Locus Coeruleus Depending on Coping Strategy. eNeuro. 2015 Nov-Dec; 2(6).
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Valentino RJ, Van Bockstaele E, Bangasser D. Sex-specific cell signaling: the corticotropin-releasing factor receptor model. Trends Pharmacol Sci. 2013 Aug; 34(8):437-44.
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Wind JJ, Lonser RR, Nieman LK, DeVroom HL, Chang R, Oldfield EH. The lateralization accuracy of inferior petrosal sinus sampling in 501 patients with Cushing's disease. J Clin Endocrinol Metab. 2013 Jun; 98(6):2285-93.