Corticotropin-Releasing Hormone
"Corticotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS.
Descriptor ID |
D003346
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MeSH Number(s) |
D06.472.699.327.740.140 D12.644.400.400.740.140 D12.644.548.365.740.140 D12.776.631.650.405.740.140
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Concept/Terms |
Corticotropin-Releasing Hormone- Corticotropin-Releasing Hormone
- Corticotropin Releasing Hormone
- Corticoliberin
- Corticotropin-Releasing Factor
- Corticotropin Releasing Factor
- Corticotropin-Releasing Factor-41
- Corticotropin Releasing Factor 41
- CRF (ACTH)
- Corticotropin-Releasing Hormone-41
- Corticotropin Releasing Hormone 41
- CRF-41
- ACTH-Releasing Hormone
- ACTH Releasing Hormone
- ACTH-Releasing Factor
- ACTH Releasing Factor
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Below are MeSH descriptors whose meaning is more general than "Corticotropin-Releasing Hormone".
Below are MeSH descriptors whose meaning is more specific than "Corticotropin-Releasing Hormone".
This graph shows the total number of publications written about "Corticotropin-Releasing Hormone" by people in this website by year, and whether "Corticotropin-Releasing Hormone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2005 | 1 | 1 | 2 |
2006 | 2 | 0 | 2 |
2007 | 1 | 1 | 2 |
2008 | 1 | 1 | 2 |
2009 | 1 | 1 | 2 |
2011 | 1 | 2 | 3 |
2012 | 2 | 0 | 2 |
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Below are the most recent publications written about "Corticotropin-Releasing Hormone" by people in Profiles.
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Lemos JC, Wanat MJ, Smith JS, Reyes BA, Hollon NG, Van Bockstaele EJ, Chavkin C, Phillips PE. Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. Nature. 2012 Oct 18; 490(7420):402-6.
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Brailoiu GC, Deliu E, Tica AA, Chitravanshi VC, Brailoiu E. Urocortin 3 elevates cytosolic calcium in nucleus ambiguus neurons. J Neurochem. 2012 Sep; 122(6):1129-36.
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Valentino RJ, Reyes B, Van Bockstaele E, Bangasser D. Molecular and cellular sex differences at the intersection of stress and arousal. Neuropharmacology. 2012 Jan; 62(1):13-20.
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Waselus M, Valentino RJ, Van Bockstaele EJ. Collateralized dorsal raphe nucleus projections: a mechanism for the integration of diverse functions during stress. J Chem Neuroanat. 2011 Jul; 41(4):266-80.
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Reyes BA, Carvalho AF, Vakharia K, Van Bockstaele EJ. Amygdalar peptidergic circuits regulating noradrenergic locus coeruleus neurons: linking limbic and arousal centers. Exp Neurol. 2011 Jul; 230(1):96-105.
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Valentino RJ, Lucki I, Van Bockstaele E. Corticotropin-releasing factor in the dorsal raphe nucleus: Linking stress coping and addiction. Brain Res. 2010 Feb 16; 1314:29-37.
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Van Bockstaele EJ, Reyes BA, Valentino RJ. The locus coeruleus: A key nucleus where stress and opioids intersect to mediate vulnerability to opiate abuse. Brain Res. 2010 Feb 16; 1314:162-74.
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Rudoy CA, Reyes AR, Van Bockstaele EJ. Evidence for beta1-adrenergic receptor involvement in amygdalar corticotropin-releasing factor gene expression: implications for cocaine withdrawal. Neuropsychopharmacology. 2009 Apr; 34(5):1135-48.
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Valentino RJ, Van Bockstaele E. Convergent regulation of locus coeruleus activity as an adaptive response to stress. Eur J Pharmacol. 2008 Apr 7; 583(2-3):194-203.
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Reyes BA, Valentino RJ, Van Bockstaele EJ. Stress-induced intracellular trafficking of corticotropin-releasing factor receptors in rat locus coeruleus neurons. Endocrinology. 2008 Jan; 149(1):122-30.