"Cross-Linking Reagents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
| Descriptor ID |
D003432
|
| MeSH Number(s) |
D27.720.470.410.210
|
| Concept/Terms |
Cross-Linking Reagents- Cross-Linking Reagents
- Reagents, Cross-Linking
- Crosslinking Reagents
- Reagents, Crosslinking
- Bifunctional Reagents
- Reagents, Bifunctional
- Cross Linking Reagents
- Linking Reagents, Cross
- Reagents, Cross Linking
|
Below are MeSH descriptors whose meaning is more general than "Cross-Linking Reagents".
Below are MeSH descriptors whose meaning is more specific than "Cross-Linking Reagents".
This graph shows the total number of publications written about "Cross-Linking Reagents" by people in this website by year, and whether "Cross-Linking Reagents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 3 | 4 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 1 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 2 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 4 | 5 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cross-Linking Reagents" by people in Profiles.
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Mhike M, Hettick JM, Chipinda I, Law BF, Bledsoe TA, Lemons AR, Nayak AP, Green BJ, Beezhold DH, Simoyi RH, Siegel PD. Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin. J Immunol Methods. 2016 Apr; 431:38-44.
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Baldwin AD, Robinson KG, Militar JL, Derby CD, Kiick KL, Akins RE. In situ crosslinkable heparin-containing poly(ethylene glycol) hydrogels for sustained anticoagulant release. J Biomed Mater Res A. 2012 Aug; 100(8):2106-18.
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Boggs ME, Thompson WR, Farach-Carson MC, Duncan RL, Beebe TP. Co-culture of osteocytes and neurons on a unique patterned surface. Biointerphases. 2011 Dec; 6(4):200-9.
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Baxter RM, Freeman TA, Kurtz SM, Steinbeck MJ. Do tissues from THA revision of highly crosslinked UHMWPE liners contain wear debris and associated inflammation? Clin Orthop Relat Res. 2011 Aug; 469(8):2308-17.
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Li L, Teller S, Clifton RJ, Jia X, Kiick KL. Tunable mechanical stability and deformation response of a resilin-based elastomer. Biomacromolecules. 2011 Jun 13; 12(6):2302-10.
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Lin LY, Lee NS, Zhu J, Nyström AM, Pochan DJ, Dorshow RB, Wooley KL. Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin. J Control Release. 2011 May 30; 152(1):37-48.
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Jha AK, Xu X, Duncan RL, Jia X. Controlling the adhesion and differentiation of mesenchymal stem cells using hyaluronic acid-based, doubly crosslinked networks. Biomaterials. 2011 Apr; 32(10):2466-78.
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Baxter RM, Ianuzzi A, Freeman TA, Kurtz SM, Steinbeck MJ. Distinct immunohistomorphologic changes in periprosthetic hip tissues from historical and highly crosslinked UHMWPE implant retrievals. J Biomed Mater Res A. 2010 Oct; 95(1):68-78.
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Donaldson JM, Kari C, Fragoso RC, Rodeck U, Williams JC. Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies. Cancer Biol Ther. 2009 Nov; 8(22):2147-52.
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Shuvaev VV, Christofidou-Solomidou M, Bhora F, Laude K, Cai H, Dikalov S, Arguiri E, Solomides CC, Albelda SM, Harrison DG, Muzykantov VR. Targeted detoxification of selected reactive oxygen species in the vascular endothelium. J Pharmacol Exp Ther. 2009 Nov; 331(2):404-11.