"Dextromethorphan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Descriptor ID |
D003915
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MeSH Number(s) |
D03.132.577.249.200 D03.605.497.212 D03.633.400.686.212 D04.615.723.795.200
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Dextromethorphan".
Below are MeSH descriptors whose meaning is more specific than "Dextromethorphan".
This graph shows the total number of publications written about "Dextromethorphan" by people in this website by year, and whether "Dextromethorphan" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2009 | 2 | 0 | 2 |
2012 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dextromethorphan" by people in Profiles.
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Ferguson GP, Achilles SL, Meyn LA, Krajewski CM, Chappell CA, Vinekar K, Chen BA. Dextromethorphan as a novel nonopioid adjunctive agent for pain control with medication abortion: A randomized controlled trial. Contraception. 2023 Feb; 118:109908.
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Logan BK, Yeakel JK, Goldfogel G, Frost MP, Sandstrom G, Wickham DJ. Dextromethorphan abuse leading to assault, suicide, or homicide. J Forensic Sci. 2012 Sep; 57(5):1388-94.
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Logan BK. Combined dextromethorphan and chlorpheniramine intoxication in impaired drivers. J Forensic Sci. 2009 Sep; 54(5):1176-80.
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Logan BK, Goldfogel G, Hamilton R, Kuhlman J. Five deaths resulting from abuse of dextromethorphan sold over the internet. J Anal Toxicol. 2009 Mar; 33(2):99-103.
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Mei Q, Tang C, Lin Y, Rushmore TH, Shou M. Inhibition kinetics of monoclonal antibodies against cytochromes P450. Drug Metab Dispos. 2002 Jun; 30(6):701-8.