Digoxin

"Digoxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)

Descriptor ID	D004077
MeSH Number(s)	D04.210.500.155.580.130.500.436 D04.210.500.155.580.130.688 D09.408.180.261.436
Concept/Terms	Digoxin Digoxin Lanacordin Lanacordin Lanicor Lanicor Lanoxicaps Lanoxicaps Dilanacin Dilanacin Digacin Digacin Digitek Digitek Digoregen Digoregen Digoxina Boehringer Digoxina Boehringer Boehringer, Digoxina Digoxine Nativelle Digoxine Nativelle Nativelle, Digoxine Hemigoxine Nativelle Nativelle, Hemigoxine Mapluxin Mapluxin Lanoxin Lanoxin Lanoxin-PG Lanoxin PG Lenoxin

Below are MeSH descriptors whose meaning is more general than "Digoxin".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Cardanolides [D04.210.500.155]
Cardiac Glycosides [D04.210.500.155.580]
Cardenolides [D04.210.500.155.580.130]
Digitalis Glycosides [D04.210.500.155.580.130.500]
Digoxin [D04.210.500.155.580.130.500.436]
Digoxin [D04.210.500.155.580.130.688]
Carbohydrates [D09]
Glycosides [D09.408]
Cardiac Glycosides [D09.408.180]
Digitalis Glycosides [D09.408.180.261]
Digoxin [D09.408.180.261.436]

Below are MeSH descriptors whose meaning is related to "Digoxin".

Below are MeSH descriptors whose meaning is more specific than "Digoxin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Digoxin" by people in this website by year, and whether "Digoxin" was a major or minor topic of these publications.

Bar chart showing 22 publications over 15 distinct years, with a maximum of 3 publications in 2005 and 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1998	0	1	1
1999	0	1	1
2000	1	1	2
2001	0	1	1
2002	0	1	1
2004	0	1	1
2005	1	2	3
2007	0	3	3
2009	0	1	1
2014	0	2	2
2015	1	0	1
2018	1	1	2
2020	0	1	1
2021	1	0	1

Below are the most recent publications written about "Digoxin" by people in Profiles.

Khodabande A, Ghassemi F, Asadi Amoli F, Riazi-Esfahani H, Mahmoudzadeh R, Mehrpour M, Valipour N. Ocular safety of repeated intravitreal injections of Carboplatin and Digoxin: A preclinical study on the healthy rabbits. Pharmacol Res Perspect. 2021 08; 9(4):e00814.

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Bosch NA, Rucci JM, Massaro JM, Winter MR, Quinn EK, Chon KH, McManus DD, Walkey AJ. Comparative Effectiveness of Heart Rate Control Medications for the Treatment of Sepsis-Associated Atrial Fibrillation. Chest. 2021 04; 159(4):1452-1459.

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Levin MD, Saitta SC, Gripp KW, Wenger TL, Ganesh J, Kalish JM, Epstein MR, Smith R, Czosek RJ, Ware SM, Goldenberg P, Myers A, Chatfield KC, Gillespie MJ, Zackai EH, Lin AE. Nonreentrant atrial tachycardia occurs independently of hypertrophic cardiomyopathy in RASopathy patients. Am J Med Genet A. 2018 08; 176(8):1711-1722.

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Ambrosy AP, Bhatt AS, Stebbins AL, Wruck LM, Fudim M, Greene SJ, Kraus WE, O'Connor CM, Pi?a IL, Whellan DJ, Mentz RJ. Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial. Am Heart J. 2018 05; 199:97-104.

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Allen LA, Fonarow GC, Simon DN, Thomas LE, Marzec LN, Pokorney SD, Gersh BJ, Go AS, Hylek EM, Kowey PR, Mahaffey KW, Chang P, Peterson ED, Piccini JP. Digoxin Use and Subsequent Outcomes Among Patients in a Contemporary Atrial Fibrillation Cohort. J Am Coll Cardiol. 2015 Jun 30; 65(25):2691-8.

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Subzposh F, Gupta A, Hankins SR, Eisen HJ. Management of ACCF/AHA Stage A and B patients. Cardiol Clin. 2014 Feb; 32(1):63-71, viii.

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Feitell S, Hankins SR, Eisen HJ. Adjunctive therapy and management of the transition of care in patients with heart failure. Cardiol Clin. 2014 Feb; 32(1):163-74, x.

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Isezuo SA, Musa AA, Saidu SA. Multiple embolisations in rheumatic heart disease: a case report. West Afr J Med. 2009 Jul-Aug; 28(4):274-6.

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Mayson SE, Greenspon AJ, Adams S, Decaro MV, Sheth M, Weitz HH, Whellan DJ. The changing face of postoperative atrial fibrillation prevention: a review of current medical therapy. Cardiol Rev. 2007 Sep-Oct; 15(5):231-41.

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Saltzman HE, Sharma K, Mather PJ, Rubin S, Adams S, Whellan DJ. Renal dysfunction in heart failure patients: what is the evidence? Heart Fail Rev. 2007 Mar; 12(1):37-47.

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