"Disopyramide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
| Descriptor ID |
D004206
|
| MeSH Number(s) |
D03.383.725.227
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Disopyramide".
Below are MeSH descriptors whose meaning is more specific than "Disopyramide".
This graph shows the total number of publications written about "Disopyramide" by people in this website by year, and whether "Disopyramide" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Disopyramide" by people in Profiles.
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Dumaine R, Antzelevitch C. Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome? J Mol Cell Cardiol. 2006 Sep; 41(3):421-3.
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Shimizu W, Antzelevitch C, Suyama K, Kurita T, Taguchi A, Aihara N, Takaki H, Sunagawa K, Kamakura S. Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. J Cardiovasc Electrophysiol. 2000 Dec; 11(12):1320-9.
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Nestico PF, Morganroth J. Antiarrhythmic agents for chronic ventricular arrhythmias. Compr Ther. 1987 Apr; 13(4):26-35.
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Nestico PF, Morganroth J. Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment. Cardiol Clin. 1986 May; 4(2):285-303.
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Nestico PF, Morganroth J. New insights into the drug treatment of ventricular arrhythmias. Int J Dermatol. 1984 Oct; 23(8):558-64.
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Nestico PF, DePace NL, Morganroth J. Therapy with conventional antiarrhythmic drugs for ventricular arrhythmias. Med Clin North Am. 1984 Sep; 68(5):1295-319.
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Kowey PR, Friedman PL, Podrid PJ, Zielonka J, Lown B, Wynne J, Holman BL. Use of radionuclide ventriculography for assessment of changes in myocardial performance induced by disopyramide phosphate. Am Heart J. 1982 Oct; 104(4 Pt 1):769-74.
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Horowitz LN, Josephson ME, Farshidi A, Spielman SR, Michelson EL, Greenspan AM. Recurrent sustained ventricular tachycardia 3. Role of the electrophysiologic study in selection of antiarrhythmic regimens. Circulation. 1978 Dec; 58(6):986-97.