Thomas Jefferson University

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Pestell, Richard
One or more keywords matched the following items that are connected to Pestell, Richard
Item TypeName
Concept Methylation
Concept RNA
Concept RNA Polymerase II
Concept RNA Precursors
Concept RNA Splicing
Concept RNA, Messenger
Concept RNA, Neoplasm
Concept RNA, Ribosomal, 18S
Concept RNA, Antisense
Concept RNA-Binding Proteins
Concept RNA Stability
Concept RNA Splice Sites
Concept RNA Interference
Concept RNA, Small Interfering
Concept RNA, Small Untranslated
Academic Article Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation.
Academic Article Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
Academic Article Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment.
Academic Article Cell fate determination factor Dachshund reprograms breast cancer stem cell function.
Academic Article Regulation of the androgen receptor by SET9-mediated methylation.
Academic Article Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.
Academic Article Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation.
Academic Article PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b.
Academic Article Mammary gland selective excision of c-jun identifies its role in mRNA splicing.
Academic Article Small non-coding RNAs govern mammary gland tumorigenesis.
Academic Article Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Academic Article p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
Academic Article Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.
Academic Article The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
Academic Article Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Academic Article Senescence and epigenetic dysregulation in cancer.
Academic Article Acetylation in hormone signaling and the cell cycle.
Academic Article Role of BRCA1 in heat shock response.
Academic Article Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1.
Academic Article Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells.
Academic Article p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.
Academic Article Intestinal tumor progression is associated with altered function of KLF5.
Academic Article Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
Academic Article SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.
Academic Article The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
Academic Article Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.
Academic Article Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells.
Academic Article Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells.
Academic Article Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
Academic Article Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3.
Academic Article Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.
Academic Article Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling.
Academic Article Cyclin D1 determines mitochondrial function in vivo.
Academic Article Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer.
Academic Article Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection.
Academic Article Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Academic Article Epigenetics and the estrogen receptor.
Academic Article ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
Academic Article Stabilization of SMAR1 mRNA by PGA2 involves a stem loop structure in the 5' UTR.
Academic Article Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migration.
Academic Article Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.
Academic Article Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB.
Academic Article Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts.
Academic Article Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
Academic Article Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
Academic Article Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo.
Academic Article The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth.
Academic Article BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.
Academic Article Angiotensin II activation of cyclin D1-dependent kinase activity.
Academic Article Reduced cyclin D1 expression in the cerebella of nutritionally deprived rats correlates with developmental delay and decreased cellular DNA synthesis.
Academic Article Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade.
Academic Article Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.
Academic Article Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.
Academic Article Cell cycle regulation and RNA polymerase II.
Academic Article Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation.
Academic Article Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.
Academic Article Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection.
Academic Article Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium.
Academic Article Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism.
Academic Article Effect of N-proopiomelanocortin (1-77) and (1-49) infusions on adrenal expression of cyclin D1 in the fetal sheep.
Academic Article Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells.
Academic Article Small RNA zippers lock miRNA molecules and block miRNA function in mammalian cells.
Academic Article Cyclin D1 integrates G9a-mediated histone methylation.
Academic Article piRNA-823 Is Involved in Cancer Stem Cell Regulation Through Altering DNA Methylation in Association With Luminal Breast Cancer.
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  • RNA
  • methylation