Thomas Jefferson University

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Eischen, Christine
One or more keywords matched the following items that are connected to Eischen, Christine
Item TypeName
Concept Carrier Proteins
Concept DNA-Binding Proteins
Concept Neoplasm Proteins
Concept Nuclear Proteins
Concept Protein Binding
Concept Protein Conformation
Concept Protein Kinases
Concept Protein Processing, Post-Translational
Concept Protein-Tyrosine Kinases
Concept Proteins
Concept Proto-Oncogene Proteins
Concept Recombinant Fusion Proteins
Concept Oncogene Proteins
Concept Tumor Suppressor Protein p53
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins p21(ras)
Concept Protein-Serine-Threonine Kinases
Concept Protein Structure, Tertiary
Concept Homeodomain Proteins
Concept ras Proteins
Concept Cell Cycle Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept Protein Isoforms
Concept rab GTP-Binding Proteins
Concept Mitogen-Activated Protein Kinase Kinases
Concept Tumor Suppressor Proteins
Concept Tumor Suppressor Protein p14ARF
Concept Intracellular Signaling Peptides and Proteins
Concept Apoptosis Regulatory Proteins
Concept bcl-X Protein
Concept bcl-2-Associated X Protein
Concept Proto-Oncogene Proteins c-mdm2
Concept ZAP-70 Protein-Tyrosine Kinase
Concept Fas Ligand Protein
Concept AMP-Activated Protein Kinases
Concept Retinoblastoma-Binding Protein 1
Academic Article Decreased Mdm2 expression inhibits tumor development induced by loss of ARF.
Academic Article Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
Academic Article Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions.
Academic Article A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.
Academic Article Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.
Academic Article Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies.
Academic Article Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.
Academic Article E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation.
Academic Article Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.
Academic Article Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Academic Article Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
Academic Article A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
Academic Article The RING domain of Mdm2 can inhibit cell proliferation.
Academic Article Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.
Academic Article The Mdm network and its regulation of p53 activities: a rheostat of cancer risk.
Academic Article Mdmx promotes genomic instability independent of p53 and Mdm2.
Academic Article Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Academic Article Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer.
Academic Article MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival.
Academic Article Decreased Mdm2 levels after DNA damage: antibody masking or protein degradation?
Academic Article Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells.
Academic Article Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.
Academic Article Mtbp haploinsufficiency in mice increases tumor metastasis.
Academic Article Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression.
Academic Article Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family.
Academic Article Mdm2 promotes genetic instability and transformation independent of p53.
Academic Article Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Academic Article Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.
Academic Article Concordant dysregulation of miR-5p and miR-3p arms of the same precursor microRNA may be a mechanism in inducing cell proliferation and tumorigenesis: a lung cancer study.
Academic Article Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis.
Academic Article Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells.
Academic Article Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
Academic Article The ARF tumor suppressor can promote the progression of some tumors.
Academic Article Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.
Academic Article PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells.
Academic Article Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model.
Academic Article Mdm2 affects genome stability independent of p53.
Academic Article p53 and MDM2: antagonists or partners in crime?
Academic Article MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Academic Article Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies.
Academic Article Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
Academic Article Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
Academic Article Murine double minute 2: p53-independent roads lead to genome instability or death.
Academic Article p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis.
Grant SMARCAL1 function in replication stress and disease
Grant MEDIATORS OF MYC INDUCED MYELOID LEUKEMIA AND APOPTOSIS
Grant Novel oncogenic functions of Mdm2 and Mdmx
Grant Novel mechanisms of oncogenic transformation in lung cancer
Grant Regulation of Myc-Mediated Tumorigenesis
Academic Article RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts.
Grant Replication stress in hematopoiesis and lymphomagenesis
Academic Article ZAP-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis.
Concept Forkhead Box Protein M1
Concept Ataxia Telangiectasia Mutated Proteins
Concept Tumor Protein p73
Grant BCLW in lymphoma survival and resistance to targeted BCL2 family therapies
Academic Article Decoding the lncRNAome Across Diverse Cellular Stresses Reveals Core p53-effector Pan-cancer Suppressive lncRNAs.
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  • GTP Binding Proteins