Thomas Jefferson University

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Eischen, Christine
One or more keywords matched the following items that are connected to Eischen, Christine
Item TypeName
Concept Adult
Concept Affinity Labels
Concept Aged
Concept Aged, 80 and over
Concept Amino Acid Sequence
Concept Animals
Concept B-Lymphocytes
Concept Base Sequence
Concept Carcinoma, Non-Small-Cell Lung
Concept Cell Cycle
Concept Cell Differentiation
Concept Cell Division
Concept Cell Line
Concept Cell Line, Transformed
Concept Cell Movement
Concept Cell Nucleus
Concept Cell Survival
Concept Cell Transformation, Neoplastic
Concept Cells, Cultured
Concept Child
Concept HeLa Cells
Concept Hematopoietic Stem Cells
Concept Heterozygote
Concept Humans
Concept Killer Cells, Natural
Concept Leukemia, Myeloid
Concept Leukocytes, Mononuclear
Concept Ligands
Concept Liver Neoplasms
Concept Longevity
Concept Lung
Concept Lung Neoplasms
Concept Lymph Nodes
Concept Lymphocyte Activation
Concept Lymphocytes
Concept Lymphoma
Concept Lymphoma, Follicular
Concept Mice, Inbred C57BL
Concept Mice, Mutant Strains
Concept Mice, Nude
Concept Mice, Transgenic
Concept Middle Aged
Concept Molecular Sequence Data
Concept Receptors, Antigen, T-Cell
Concept Receptors, Cell Surface
Concept Retroviridae
Concept Stem Cells
Concept Streptococcus pneumoniae
Concept T-Lymphocytes
Concept Tumor Cells, Cultured
Concept Leukemia, T-Cell
Concept Leukemia-Lymphoma, Adult T-Cell
Concept Leukemia, Myeloid, Acute
Concept Hematopoietic Cell Growth Factors
Concept Lymphoma, B-Cell
Concept Lymphoma, Large B-Cell, Diffuse
Concept Lymphoma, T-Cell, Cutaneous
Concept 3T3 Cells
Concept Mice, SCID
Concept Cell Death
Concept Mice, Knockout
Concept Systems Integration
Concept Cell Cycle Proteins
Concept Jurkat Cells
Concept Computational Biology
Concept K562 Cells
Concept In Situ Nick-End Labeling
Concept Dromaiidae
Concept Myeloid Cells
Concept Animals, Genetically Modified
Concept Lamins
Concept Lamin Type B
Concept NIH 3T3 Cells
Concept Cell Line, Tumor
Concept Cell Growth Processes
Concept Cell Proliferation
Concept Mice
Concept Rats
Concept Fas Ligand Protein
Concept Precursor Cells, B-Lymphoid
Concept Mice, 129 Strain
Concept HEK293 Cells
Concept Cell Cycle Checkpoints
Concept MCF-7 Cells
Concept RNA, Long Noncoding
Academic Article Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution.
Academic Article Decreased Mdm2 expression inhibits tumor development induced by loss of ARF.
Academic Article Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
Academic Article Role of MDM2 and MDMX in DNA repair.
Academic Article Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions.
Academic Article A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.
Academic Article Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.
Academic Article Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies.
Academic Article Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma.
Academic Article Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.
Academic Article MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.
Academic Article Genetic markers associated with progression in early mycosis fungoides.
Academic Article E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation.
Academic Article Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.
Academic Article Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Academic Article Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus.
Academic Article Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
Academic Article miR-223 regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma.
Academic Article A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
Academic Article The RING domain of Mdm2 can inhibit cell proliferation.
Academic Article Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.
Academic Article The Mdm network and its regulation of p53 activities: a rheostat of cancer risk.
Academic Article Mdmx promotes genomic instability independent of p53 and Mdm2.
Academic Article Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Academic Article Inactivation of p53 is insufficient to allow B cells and B-cell lymphomas to survive without Dicer.
Academic Article MTBP is overexpressed in triple-negative breast cancer and contributes to its growth and survival.
Academic Article Early changes in miRNA expression are predictive of response to extracorporeal photopheresis in cutaneous T-cell lymphoma.
Academic Article Decreased Mdm2 levels after DNA damage: antibody masking or protein degradation?
Academic Article Reproducible combinatorial regulatory networks elucidate novel oncogenic microRNAs in non-small cell lung cancer.
Academic Article Differences in miRNA expression in early stage lung adenocarcinomas that did and did not relapse.
Academic Article Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells.
Academic Article Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.
Academic Article Mtbp haploinsufficiency in mice increases tumor metastasis.
Academic Article Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression.
Academic Article Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family.
Academic Article Cell survival is dicey without Dicer.
Academic Article Mdm2 promotes genetic instability and transformation independent of p53.
Academic Article Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Academic Article Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.
Academic Article Concordant dysregulation of miR-5p and miR-3p arms of the same precursor microRNA may be a mechanism in inducing cell proliferation and tumorigenesis: a lung cancer study.
Academic Article Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis.
Academic Article Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells.
Academic Article Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides.
Academic Article Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
Academic Article The ARF tumor suppressor can promote the progression of some tumors.
Academic Article Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.
Academic Article PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells.
Academic Article Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model.
Academic Article Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.
Academic Article Mdm2 affects genome stability independent of p53.
Academic Article p53 and MDM2: antagonists or partners in crime?
Academic Article SMARCAL1 maintains telomere integrity during DNA replication.
Academic Article MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Academic Article Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies.
Academic Article Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
Academic Article Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
Academic Article Murine double minute 2: p53-independent roads lead to genome instability or death.
Academic Article Histone deacetylase inhibition reveals a tumor-suppressive function of MYC-regulated miRNA in breast and lung carcinoma.
Academic Article miR-31 and miR-17-5p levels change during transformation of follicular lymphoma.
Academic Article Molecular underpinnings of HDAC inhibition revealed.
Academic Article TOX expression and role in CTCL.
Academic Article p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis.
Grant p53-Independent Pathways in Mdm2-Mediated Transformation
Grant SMARCAL1 function in replication stress and disease
Grant MEDIATORS OF MYC INDUCED MYELOID LEUKEMIA AND APOPTOSIS
Grant Myc-induced pathways in B cell lymphoma initiation and survival
Grant Novel oncogenic functions of Mdm2 and Mdmx
Grant Novel mechanisms of oncogenic transformation in lung cancer
Grant Regulation of Myc-Mediated Tumorigenesis
Grant The Role of Mdm2 in Lymphoma Development
Academic Article Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer.
Academic Article Mdm2 Is Required for Survival and Growth of p53-Deficient Cancer Cells.
Academic Article The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development.
Academic Article BCL-W has a fundamental role in B cell survival and lymphomagenesis.
Academic Article Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition.
Academic Article Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition.
Academic Article Non-Hodgkin and Hodgkin Lymphomas Select for Overexpression of BCLW.
Academic Article Targeting of SGK1 by miR-576-3p inhibits lung adenocarcinoma migration and invasion.
Academic Article The proto-oncogene function of Mdm2 in bone.
Grant Replication stress in hematopoiesis and lymphomagenesis
Academic Article Targeting the Bcl-2 Family in B Cell Lymphoma.
Academic Article The Role of Inhibition of Apoptosis in Acute Leukemias and Myelodysplastic Syndrome.
Academic Article miR-21 is required for hematopoietic cell viability following radiation exposure.
Academic Article IL-33 Is a Cell-Intrinsic Regulator of Fitness during Early B Cell Development.
Academic Article ZAP-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis.
Academic Article Targeting BCL-W and BCL-XL as a therapeutic strategy for Hodgkin lymphoma.
Concept Gene Ontology
Grant BCLW in lymphoma survival and resistance to targeted BCL2 family therapies
Academic Article Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance.
Academic Article MicroRNA and transcription factor co-regulatory networks and subtype classification of seminoma and non-seminoma in testicular germ cell tumors.
Academic Article Targeting MYC through WDR5.
Academic Article MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor-1.
Academic Article miRcorrNet: machine learning-based integration of miRNA and mRNA expression profiles, combined with feature grouping and ranking.
Academic Article Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression.
Academic Article Systematic lncRNA mapping to genome-wide co-essential modules uncovers cancer dependency on uncharacterized lncRNAs.
Academic Article Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming.
Academic Article Engaging community members in cancer research: an assessment of an NCI-designated cancer center.
Academic Article CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research.
Academic Article Decoding the lncRNAome Across Diverse Cellular Stresses Reveals Core p53-effector Pan-cancer Suppressive lncRNAs.
Academic Article 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Grant Investigating a new vulnerability in oral squamous cell carcinoma
Grant A Next-Generation Nucleoside Prodrug for Diffuse Large B-Cell Lymphoma
Academic Article Identifying Targetable Vulnerabilities to Circumvent or Overcome Venetoclax Resistance in Diffuse Large B-Cell Lymphoma.
Academic Article DNA fork remodeling proteins, Zranb3 and Smarcal1, are uniquely essential for aging hematopoiesis.
Academic Article Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis.
Academic Article Isokinetic leg flexion and extension strength of university football players.
Academic Article The Fas pathway in apoptosis.
Academic Article Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis.
Academic Article Role for NK-cell-associated Fas ligand in cell-mediated cytotoxicity and apoptosis.
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