Thomas Jefferson University

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Eischen, Christine
One or more keywords matched the following items that are connected to Eischen, Christine
Item TypeName
Concept Proto-Oncogene Proteins
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-mdm2
Academic Article Decreased Mdm2 expression inhibits tumor development induced by loss of ARF.
Academic Article Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
Academic Article A deficiency in Mdm2 binding protein inhibits Myc-induced B-cell proliferation and lymphomagenesis.
Academic Article Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies.
Academic Article Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis.
Academic Article Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis.
Academic Article Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Academic Article Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.
Academic Article A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
Academic Article The RING domain of Mdm2 can inhibit cell proliferation.
Academic Article Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.
Academic Article The Mdm network and its regulation of p53 activities: a rheostat of cancer risk.
Academic Article Mdmx promotes genomic instability independent of p53 and Mdm2.
Academic Article Oncogenic protein MTBP interacts with MYC to promote tumorigenesis.
Academic Article Decreased Mdm2 levels after DNA damage: antibody masking or protein degradation?
Academic Article Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells.
Academic Article Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis.
Academic Article Mtbp haploinsufficiency in mice increases tumor metastasis.
Academic Article Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression.
Academic Article Mdm2 promotes genetic instability and transformation independent of p53.
Academic Article Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.
Academic Article Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis.
Academic Article Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells.
Academic Article Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
Academic Article Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development.
Academic Article Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model.
Academic Article Mdm2 affects genome stability independent of p53.
Academic Article p53 and MDM2: antagonists or partners in crime?
Academic Article MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer.
Academic Article Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies.
Academic Article Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
Academic Article Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
Academic Article Murine double minute 2: p53-independent roads lead to genome instability or death.
Academic Article p53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis.
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  • Proto Oncogene Proteins