Thomas Jefferson University

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Sigal, Luis
One or more keywords matched the following items that are connected to Sigal, Luis
Item TypeName
Concept Antigen-Presenting Cells
Concept B-Lymphocytes
Concept Bone Marrow Cells
Concept Cells, Cultured
Concept Dendritic Cells
Concept HeLa Cells
Concept T-Lymphocytes, Helper-Inducer
Concept Hematopoietic Stem Cells
Concept Killer Cells, Natural
Concept Langerhans Cells
Concept Lymphocytes
Concept Stem Cells
Concept T-Lymphocytes
Concept T-Lymphocytes, Cytotoxic
Concept Tumor Cells, Cultured
Concept Vero Cells
Concept CD4-Positive T-Lymphocytes
Concept T-Lymphocyte Subsets
Concept Receptors, Antigen, T-Cell, gamma-delta
Concept Stromal Cells
Concept CD8-Positive T-Lymphocytes
Concept Th1 Cells
Concept Epitopes, T-Lymphocyte
Concept K562 Cells
Concept T-Lymphocytes, Regulatory
Academic Article Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection.
Academic Article Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responses.
Academic Article Studying NK cell responses to ectromelia virus infections in mice.
Academic Article Memory CD8? T cells can outsource IFN-? production but not cytolytic killing for antiviral protection.
Academic Article Direct presentation is sufficient for an efficient anti-viral CD8+ T cell response.
Academic Article Direct CD28 costimulation is required for CD8+ T cell-mediated resistance to an acute viral disease in a natural host.
Academic Article Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking.
Academic Article Memory CD8+ T cells are gatekeepers of the lymph node draining the site of viral infection.
Academic Article Macrophages and dendritic cells use the cytosolic pathway to rapidly cross-present antigen from live, vaccinia-infected cells.
Academic Article CD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization.
Academic Article A role for NKG2D in NK cell-mediated resistance to poxvirus disease.
Academic Article Gamma interferon and perforin control the strength, but not the hierarchy, of immunodominance of an antiviral CD8+ T cell response.
Academic Article Protective CD8+ T cell memory without help.
Academic Article Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease.
Academic Article Immunization with a single extracellular enveloped virus protein produced in bacteria provides partial protection from a lethal orthopoxvirus infection in a natural host.
Academic Article Antibodies and CD8+ T cells are complementary and essential for natural resistance to a highly lethal cytopathic virus.
Academic Article Memory CD8? T cell protection.
Academic Article The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by IL-15/IL-15Ra treatment.
Academic Article Cutting Edge: Protection by Antiviral Memory CD8 T Cells Requires Rapidly Produced Antigen in Large Amounts.
Academic Article Cutting edge: efficient MHC class I cross-presentation during early vaccinia infection requires the transfer of proteasomal intermediates between antigen donor and presenting cells.
Academic Article The multiple routes of MHC-I cross-presentation.
Academic Article CD94 is essential for NK cell-mediated resistance to a lethal viral disease.
Academic Article Development and function of CD94-deficient natural killer cells.
Academic Article Enhanced NK-cell development and function in BCAP-deficient mice.
Academic Article Cross priming or direct priming: is that really the question?
Academic Article Immunology: Memory cells sound the alarm.
Academic Article Migratory Dendritic Cells, Group 1 Innate Lymphoid Cells, and Inflammatory Monocytes Collaborate to Recruit NK Cells to the Virus-Infected Lymph Node.
Academic Article Chronic Lymphocytic Choriomeningitis Infection Causes Susceptibility to Mousepox and Impairs Natural Killer Cell Maturation and Function.
Academic Article Loss of Resistance to Mousepox during Chronic Lymphocytic Choriomeningitis Virus Infection Is Associated with Impaired T-Cell Responses and Can Be Rescued by Immunization.
Academic Article Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node.
Academic Article Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy.
Academic Article a2?1 Integrin Is Required for Optimal NK Cell Proliferation during Viral Infection but Not for Acquisition of Effector Functions or NK Cell-Mediated Virus Control.
Academic Article Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation.
Academic Article Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging.
Academic Article Dysregulated anti-viral innate immune cascade during aging.
Academic Article Viral infection modulates Qa-1b in infected and bystander cells to properly direct NK cell killing.
Academic Article Mechanisms of Antiviral Cytotoxic CD4 T Cell Differentiation.
Academic Article A virus-encoded type I interferon decoy receptor enables evasion of host immunity through cell-surface binding.
Academic Article Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T?cells against a lethal viral infection.
Academic Article Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells.
Academic Article IFN-? Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells.
Academic Article Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine.
Academic Article Multiple and Consecutive Genome Editing Using i-GONAD and Breeding Enrichment Facilitates the Production of Genetically Modified Mice.
Academic Article Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15.
Academic Article mRNA-LNP vaccine-induced CD8+ T?cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies.
Academic Article Innate and adaptive immune responses that control lymph-borne viruses in the draining lymph node.
Academic Article The roles of CD4+ T?cell help, sex, and dose in the induction of protective CD8+ T?cells against a lethal poxvirus by mRNA-LNP vaccines.
Academic Article Changes in mononuclear peripheral blood cells in cattle with foot-and-mouth disease.
Academic Article The role of B7-1 and B7-2 costimulation for the generation of CTL responses in vivo.
Academic Article Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen.
Academic Article Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and -independent pathways of antigen presentation.
Academic Article Poliovirus vaccine vectors elicit antigen-specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen.
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