Thomas Jefferson University

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Fleming, Robert
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Academic Article Pathogenesis of hereditary hemochromatosis: genetics and beyond.
Academic Article Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2.
Academic Article Decreased liver hepcidin expression in the Hfe knockout mouse.
Academic Article Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis.
Academic Article Orchestration of iron homeostasis.
Academic Article Contribution of the H63D mutation in HFE to murine hereditary hemochromatosis.
Academic Article Pathophysiology of hereditary hemochromatosis.
Academic Article Genetic study of variation in normal mouse iron homeostasis reveals ceruloplasmin as an HFE-hemochromatosis modifier gene.
Academic Article Expression of iron-related genes in human brain and brain tumors.
Academic Article Iron Imports. VI. HFE and regulation of intestinal iron absorption.
Academic Article HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron.
Academic Article Iron sensing as a partnership: HFE and transferrin receptor 2.
Academic Article The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice.
Academic Article Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
Academic Article Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum.
Academic Article Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
Academic Article Novel observations in hereditary hemochromatosis: potential implications for clinical strategies.
Academic Article Associations of common variants in HFE and TMPRSS6 with iron parameters are independent of serum hepcidin in a general population: a replication study.
Academic Article Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.
Concept Hemochromatosis Protein
Academic Article Transferrin receptor 1: keeper of HFE.
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  • Hemochromatosis Protein