Item Type | Name |
Concept
|
Abdominal Muscles
|
Concept
|
Acute Disease
|
Concept
|
Adenine
|
Concept
|
Cyclic AMP
|
Concept
|
Adenosine Diphosphate
|
Concept
|
Adenosine Monophosphate
|
Concept
|
Animals
|
Concept
|
Anti-Inflammatory Agents
|
Concept
|
Antibodies
|
Concept
|
Anticholesteremic Agents
|
Concept
|
Anticoagulants
|
Concept
|
Aorta
|
Concept
|
Aorta, Thoracic
|
Concept
|
Arterioles
|
Concept
|
Binding Sites
|
Concept
|
Biological Transport
|
Concept
|
Bird Diseases
|
Concept
|
Birds
|
Concept
|
Bleeding Time
|
Concept
|
Blood Cell Count
|
Concept
|
Blood Coagulation
|
Concept
|
Blood Coagulation Factors
|
Concept
|
Blood Flow Velocity
|
Concept
|
Blood Glucose
|
Concept
|
Blood Platelets
|
Concept
|
Body Weight
|
Concept
|
Calcium
|
Concept
|
Calpain
|
Concept
|
Chemotaxis, Leukocyte
|
Concept
|
Chickens
|
Concept
|
Clot Retraction
|
Concept
|
Cricetulus
|
Concept
|
Cytoplasmic Granules
|
Concept
|
Cytoskeleton
|
Concept
|
Diabetes Mellitus, Experimental
|
Concept
|
Diabetes Mellitus, Type 2
|
Concept
|
Diabetic Angiopathies
|
Concept
|
Diffusion
|
Concept
|
Disease Models, Animal
|
Concept
|
Drug Synergism
|
Concept
|
Electrocardiography
|
Concept
|
Endothelium, Vascular
|
Concept
|
Enzyme Activation
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Escherichia coli
|
Concept
|
Biological Evolution
|
Concept
|
Exons
|
Concept
|
Femoral Artery
|
Concept
|
Fibrin
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Fluorescent Dyes
|
Concept
|
Fluorobenzenes
|
Concept
|
Glucose
|
Concept
|
Cricetinae
|
Concept
|
Hemostasis
|
Concept
|
Hemostatics
|
Concept
|
Humans
|
Concept
|
Hyperglycemia
|
Concept
|
Hyperlipidemias
|
Concept
|
Hyperplasia
|
Concept
|
Hypoglycemic Agents
|
Concept
|
Ileum
|
Concept
|
Immunohistochemistry
|
Concept
|
Indoles
|
Concept
|
Infertility
|
Concept
|
Inflammation
|
Concept
|
Insulin
|
Concept
|
Intercellular Junctions
|
Concept
|
Isomerism
|
Concept
|
Kinetics
|
Concept
|
Leukocyte Count
|
Concept
|
Leukocytes
|
Concept
|
Ligands
|
Concept
|
Liposomes
|
Concept
|
Longevity
|
Concept
|
Lung Neoplasms
|
Concept
|
Lymphoid Tissue
|
Concept
|
Lysosomes
|
Concept
|
Macrophages
|
Concept
|
Maleimides
|
Concept
|
Mammals
|
Concept
|
Megakaryocytes
|
Concept
|
Melanoma, Experimental
|
Concept
|
Mesentery
|
Concept
|
Mevalonic Acid
|
Concept
|
Mice, Inbred C3H
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Microcirculation
|
Concept
|
Microfilament Proteins
|
Concept
|
Actin Cytoskeleton
|
Concept
|
Microscopy
|
Concept
|
Models, Biological
|
Concept
|
Models, Cardiovascular
|
Concept
|
Multienzyme Complexes
|
Concept
|
Myeloproliferative Disorders
|
Concept
|
Myocardium
|
Concept
|
Neoplasms, Experimental
|
Concept
|
Neovascularization, Pathologic
|
Concept
|
Neutrophils
|
Concept
|
Nitric Oxide
|
Concept
|
Phosphatidylserines
|
Concept
|
Phosphorylation
|
Concept
|
Platelet Adhesiveness
|
Concept
|
Platelet Aggregation
|
Concept
|
Platelet Aggregation Inhibitors
|
Concept
|
Platelet Count
|
Concept
|
Platelet Membrane Glycoproteins
|
Concept
|
Poultry Diseases
|
Concept
|
Protein Binding
|
Concept
|
Rats, Zucker
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Endosomes
|
Concept
|
Regional Blood Flow
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Splanchnic Circulation
|
Concept
|
Sulfonamides
|
Concept
|
Superoxides
|
Concept
|
Thrombin
|
Concept
|
Thromboembolism
|
Concept
|
Thromboplastin
|
Concept
|
Thromboxane A2
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Tyrosine
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
Signal Transduction
|
Concept
|
Reperfusion Injury
|
Concept
|
Myocardial Reperfusion Injury
|
Concept
|
Platelet Activation
|
Concept
|
Inositol 1,4,5-Trisphosphate
|
Concept
|
Cell Degranulation
|
Concept
|
Antigens, CD
|
Concept
|
Cell Adhesion Molecules
|
Concept
|
Factor Xa
|
Concept
|
Integrins
|
Concept
|
Granulocyte Colony-Stimulating Factor
|
Concept
|
Lysosomal Storage Diseases
|
Concept
|
CHO Cells
|
Concept
|
Laser-Doppler Flowmetry
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Rats, Wistar
|
Concept
|
Gene Deletion
|
Concept
|
Alternative Splicing
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Gap Junctions
|
Concept
|
Connexins
|
Concept
|
Genes, Reporter
|
Concept
|
Receptors, Purinergic P2
|
Concept
|
Phosphatidylinositol Phosphates
|
Concept
|
Receptors, Thrombin
|
Concept
|
Mice, Knockout
|
Concept
|
Muscle, Skeletal
|
Concept
|
Microscopy, Video
|
Concept
|
Intercellular Adhesion Molecule-1
|
Concept
|
HSP90 Heat-Shock Proteins
|
Concept
|
Immunity, Mucosal
|
Concept
|
Nitric Oxide Synthase
|
Concept
|
P-Selectin
|
Concept
|
Vascular Cell Adhesion Molecule-1
|
Concept
|
Platelet Glycoprotein GPIIb-IIIa Complex
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
Concept
|
GTP-Binding Proteins
|
Concept
|
NADPH Oxidases
|
Concept
|
Phosphatidylinositol 4,5-Diphosphate
|
Concept
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
Concept
|
Hematologic Neoplasms
|
Concept
|
Integrases
|
Concept
|
Phosphatidylinositol 3-Kinases
|
Concept
|
Amino Acid Substitution
|
Concept
|
Mutation, Missense
|
Concept
|
Surface Plasmon Resonance
|
Concept
|
GTPase-Activating Proteins
|
Concept
|
RGS Proteins
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
Concept
|
Protein Transport
|
Concept
|
Secretory Vesicles
|
Concept
|
Hermanski-Pudlak Syndrome
|
Concept
|
Animals, Genetically Modified
|
Concept
|
Vesicular Transport Proteins
|
Concept
|
Adaptor Protein Complex 3
|
Concept
|
Receptor, EphA4
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Ephrin-B1
|
Concept
|
Semaphorins
|
Concept
|
Platelet Membrane Glycoprotein IIb
|
Concept
|
Endothelial Cells
|
Concept
|
Receptors, G-Protein-Coupled
|
Concept
|
Microfluidics
|
Concept
|
Microfluidic Analytical Techniques
|
Concept
|
Multiprotein Complexes
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Immunoprecipitation
|
Concept
|
Phospholipid Transfer Proteins
|
Concept
|
Atherosclerosis
|
Concept
|
SNARE Proteins
|
Concept
|
STAT5 Transcription Factor
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
Mice
|
Concept
|
Rats
|
Concept
|
ADAM Proteins
|
Concept
|
GTP-Binding Protein alpha Subunit, Gi2
|
Concept
|
Phospholipase C gamma
|
Concept
|
Adiponectin
|
Concept
|
Nitric Oxide Synthase Type II
|
Concept
|
Nitric Oxide Synthase Type III
|
Concept
|
Janus Kinase 2
|
Concept
|
Laser Therapy
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 6
|
Concept
|
rho-Associated Kinases
|
Concept
|
Cell-Derived Microparticles
|
Concept
|
AMP-Activated Protein Kinases
|
Concept
|
Purinergic P2 Receptor Antagonists
|
Concept
|
Purinergic P2Y Receptor Antagonists
|
Concept
|
Receptors, Purinergic P2Y12
|
Concept
|
Proteolysis
|
Academic Article
|
JAM-A protects from thrombosis by suppressing integrin aIIbß3-dependent outside-in signaling in platelets.
|
Concept
|
In Vitro Techniques
|
Concept
|
Myristoylated Alanine-Rich C Kinase Substrate
|
Concept
|
c-Mer Tyrosine Kinase
|
Concept
|
ADAM17 Protein
|
Concept
|
Syk Kinase
|
Concept
|
Rosuvastatin Calcium
|
Concept
|
Intravital Microscopy
|
Academic Article
|
GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets.
|
Academic Article
|
Platelets and hemostasis: a new perspective on an old subject.
|
Academic Article
|
RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists.
|
Academic Article
|
RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury.
|
Academic Article
|
Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.
|
Academic Article
|
Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice.
|
Academic Article
|
A systems approach to hemostasis: 3. Thrombus consolidation regulates intrathrombus solute transport and local thrombin activity.
|
Academic Article
|
Loss of pleckstrin-2 reverts lethality and vascular occlusions in JAK2V617F-positive myeloproliferative neoplasms.
|
Academic Article
|
A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature.
|
Academic Article
|
Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network.
|
Academic Article
|
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.
|
Academic Article
|
Shaping the platelet response to vascular injury.
|
Academic Article
|
Phosphatidylinositol transfer protein-a in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis.
|
Academic Article
|
Inhibition of Rho-kinase attenuates endothelial-leukocyte interaction during ischemia-reperfusion injury.
|
Academic Article
|
Boundary events: contact-dependent and contact-facilitated signaling between platelets.
|
Academic Article
|
Platelets lacking PIP5KI? have normal integrin activation but impaired cytoskeletal-membrane integrity and adhesion.
|
Academic Article
|
Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease.
|
Academic Article
|
A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment.
|
Academic Article
|
Regulation of Platelet Activation and Coagulation and Its Role in Vascular Injury and Arterial Thrombosis.
|
Academic Article
|
Mouse laser injury models: variations on a theme.
|
Academic Article
|
A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling.
|
Academic Article
|
Use of electron microscopy to study platelets and thrombi.
|
Academic Article
|
Peptides derived from MARCKS block coagulation complex assembly on phosphatidylserine.
|
Academic Article
|
The calcium-dependent protease calpain causes endothelial dysfunction in type 2 diabetes.
|
Academic Article
|
Mechanisms of amelioration of glucose-induced endothelial dysfunction following inhibition of protein kinase C in vivo.
|
Academic Article
|
Harnessing the platelet signaling network to produce an optimal hemostatic response.
|
Academic Article
|
Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.
|
Academic Article
|
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.
|
Academic Article
|
Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis.
|
Academic Article
|
Minding the gaps--and the junctions, too.
|
Academic Article
|
Simulation of intrathrombus fluid and solute transport using in vivo clot structures with single platelet resolution.
|
Academic Article
|
A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets.
|
Academic Article
|
Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.
|
Academic Article
|
Mouse models of platelet function in vivo.
|
Academic Article
|
A novel role for calpains in the endothelial dysfunction of hyperglycemia.
|
Academic Article
|
Interrelationships between structure and function during the hemostatic response to injury.
|
Academic Article
|
Microcirculation as a target for the anti-inflammatory properties of statins.
|
Academic Article
|
Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes.
|
Academic Article
|
Novel therapeutic targets at the platelet vascular interface.
|
Academic Article
|
Platelet signaling.
|
Academic Article
|
Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation.
|
Academic Article
|
Minding the gaps to promote thrombus growth and stability.
|
Academic Article
|
Defective release of a granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.
|
Academic Article
|
Contact-dependent signaling events that promote thrombus formation.
|
Academic Article
|
The contribution of TFPIa to the hemostatic response to injury in mice.
|
Academic Article
|
Elevated ambient glucose induces acute inflammatory events in the microvasculature: effects of insulin.
|
Academic Article
|
The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.
|
Academic Article
|
Myocardial ischemia/reperfusion injury in NADPH oxidase-deficient mice.
|
Academic Article
|
Hierarchical organization of the hemostatic response to penetrating injuries in the mouse macrovasculature.
|
Academic Article
|
Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.
|
Academic Article
|
Spatiotemporal regulation of coagulation and platelet activation during the hemostatic response in vivo.
|
Academic Article
|
Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo.
|
Academic Article
|
Platelet packing density is an independent regulator of the hemostatic response to injury.
|
Academic Article
|
A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid.
|
Academic Article
|
Thrombin spatial distribution determines Protein C activation during hemostasis and thrombosis.
|
Academic Article
|
GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y12.
|