Item Type | Name |
Concept
|
Aged
|
Concept
|
Animals
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Antibodies, Neoplasm
|
Concept
|
Antigens, Differentiation, T-Lymphocyte
|
Concept
|
Antigens, Ly
|
Concept
|
Antineoplastic Agents
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
Concept
|
Autoantigens
|
Concept
|
Base Sequence
|
Concept
|
Benzamides
|
Concept
|
Biological Transport
|
Concept
|
Biphenyl Compounds
|
Concept
|
Blast Crisis
|
Concept
|
Cell Count
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Division
|
Concept
|
Cell Line, Transformed
|
Concept
|
Cell Movement
|
Concept
|
Cell Nucleus
|
Concept
|
Cell Transformation, Neoplastic
|
Concept
|
Cysteine Endopeptidases
|
Concept
|
Cytarabine
|
Concept
|
Cytoplasm
|
Concept
|
Cytotoxicity Tests, Immunologic
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Drug Synergism
|
Concept
|
Enzyme Activation
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Herpesvirus 4, Human
|
Concept
|
Flow Cytometry
|
Concept
|
Colforsin
|
Concept
|
Genes, Homeobox
|
Concept
|
Granulocytes
|
Concept
|
Growth Substances
|
Concept
|
Hematopoietic Stem Cells
|
Concept
|
Humans
|
Concept
|
Immune Tolerance
|
Concept
|
Immunoglobulin Fc Fragments
|
Concept
|
Inflammation
|
Concept
|
Inositol Phosphates
|
Concept
|
Interferon-gamma
|
Concept
|
Interleukin-1
|
Concept
|
Interleukin-2
|
Concept
|
Interleukins
|
Concept
|
Killer Cells, Natural
|
Concept
|
Leukemia
|
Concept
|
Lymphocyte Activation
|
Concept
|
Lymphocytes
|
Concept
|
Lymphoma
|
Concept
|
Macrophages
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Mutant Strains
|
Concept
|
Mice, Transgenic
|
Concept
|
Middle Aged
|
Concept
|
Plicamycin
|
Concept
|
Molecular Sequence Data
|
Concept
|
Monocytes
|
Concept
|
Multienzyme Complexes
|
Concept
|
Neutrophils
|
Concept
|
Oligodeoxyribonucleotides
|
Concept
|
Phagocytosis
|
Concept
|
Phenylurea Compounds
|
Concept
|
Phosphorylation
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Propylene Glycols
|
Concept
|
Protein Binding
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Ribonucleoproteins
|
Concept
|
RNA, Messenger
|
Concept
|
RNA, Neoplasm
|
Concept
|
Sequence Homology, Nucleic Acid
|
Concept
|
Sphingosine
|
Concept
|
Superoxides
|
Concept
|
Thiazoles
|
Concept
|
Palatine Tonsil
|
Concept
|
Transcription, Genetic
|
Concept
|
Protein Biosynthesis
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Northern
|
Concept
|
Blotting, Western
|
Concept
|
Molecular Structure
|
Concept
|
Signal Transduction
|
Concept
|
Leukemia, B-Cell
|
Concept
|
Leukemia, Lymphocytic, Chronic, B-Cell
|
Concept
|
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
|
Concept
|
Leukemia, Myeloid, Acute
|
Concept
|
Down-Regulation
|
Concept
|
Antigens, CD
|
Concept
|
Monokines
|
Concept
|
Interleukin-6
|
Concept
|
Up-Regulation
|
Concept
|
Gene Expression Regulation, Leukemic
|
Concept
|
Fusion Proteins, bcr-abl
|
Concept
|
Lymphocyte Subsets
|
Concept
|
Genes, Tumor Suppressor
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
T-Lymphocyte Subsets
|
Concept
|
Receptors, Granulocyte Colony-Stimulating Factor
|
Concept
|
Cytokines
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Genes, myc
|
Concept
|
Genes, abl
|
Concept
|
Sp1 Transcription Factor
|
Concept
|
Lymphoma, B-Cell
|
Concept
|
Mice, SCID
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Culture Media, Serum-Free
|
Concept
|
Conserved Sequence
|
Concept
|
Apoptosis
|
Concept
|
Receptors, IgG
|
Concept
|
Receptors, Interleukin
|
Concept
|
Receptors, Aryl Hydrocarbon
|
Concept
|
Mice, Knockout
|
Concept
|
Homeodomain Proteins
|
Concept
|
Disease Progression
|
Concept
|
Microscopy, Confocal
|
Concept
|
ras Proteins
|
Concept
|
Interleukin-12
|
Concept
|
HL-60 Cells
|
Concept
|
Antigens, CD19
|
Concept
|
Antigens, CD20
|
Concept
|
Antigens, CD34
|
Concept
|
CD56 Antigen
|
Concept
|
Proto-Oncogene Proteins c-kit
|
Concept
|
L-Selectin
|
Concept
|
Cell Lineage
|
Concept
|
Stem Cell Factor
|
Concept
|
DNA Methylation
|
Concept
|
Adoptive Transfer
|
Concept
|
Interleukin-15
|
Concept
|
Phosphatidylinositol 3-Kinases
|
Concept
|
Leukopoiesis
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
Concept
|
K562 Cells
|
Concept
|
Tyrphostins
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Interleukin-18
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
Gene Duplication
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
CCAAT-Enhancer-Binding Protein-alpha
|
Concept
|
CCAAT-Enhancer-Binding Protein-beta
|
Concept
|
Myeloid Progenitor Cells
|
Concept
|
Electrophoretic Mobility Shift Assay
|
Concept
|
Ubiquitin
|
Concept
|
Heterogeneous-Nuclear Ribonucleoproteins
|
Concept
|
Heterogeneous-Nuclear Ribonucleoprotein Group A-B
|
Concept
|
RNA, Small Interfering
|
Concept
|
MicroRNAs
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Lectins, C-Type
|
Concept
|
Cell Line, Tumor
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Cell Proliferation
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
STAT4 Transcription Factor
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
PTEN Phosphohydrolase
|
Concept
|
Cyclin-Dependent Kinase 4
|
Concept
|
Mice
|
Concept
|
GRB2 Adaptor Protein
|
Concept
|
Proto-Oncogene Proteins c-pim-1
|
Concept
|
Proto-Oncogene Proteins c-mdm2
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
Concept
|
Smad2 Protein
|
Concept
|
Smad3 Protein
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily D
|
Concept
|
fms-Like Tyrosine Kinase 3
|
Concept
|
Benzothiazoles
|
Concept
|
Membrane Potential, Mitochondrial
|
Concept
|
Receptors, Interleukin-1 Type I
|
Concept
|
Interleukin Receptor Common gamma Subunit
|
Concept
|
Interleukin-2 Receptor beta Subunit
|
Concept
|
Receptors, Interleukin-12
|
Concept
|
Leukemia, Large Granular Lymphocytic
|
Concept
|
Precursor Cell Lymphoblastic Leukemia-Lymphoma
|
Concept
|
Precursor Cells, B-Lymphoid
|
Concept
|
Protein Phosphatase 2
|
Concept
|
Natural Killer T-Cells
|
Concept
|
Natural Cytotoxicity Triggering Receptor 1
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily A
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily C
|
Concept
|
Histone Chaperones
|
Concept
|
HEK293 Cells
|
Concept
|
GPI-Linked Proteins
|
Concept
|
Topoisomerase II Inhibitors
|
Concept
|
Proteolysis
|
Concept
|
Real-Time Polymerase Chain Reaction
|
Academic Article
|
BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.
|
Academic Article
|
hnRNP A1 nucleocytoplasmic shuttling activity is required for normal myelopoiesis and BCR/ABL leukemogenesis.
|
Academic Article
|
BCR/ABL activates mdm2 mRNA translation via the La antigen.
|
Academic Article
|
Altered mRNA translation: possible mechanism for CML disease progression.
|
Academic Article
|
High levels of the BCR/ABL oncoprotein are required for the MAPK-hnRNP-E2 dependent suppression of C/EBPalpha-driven myeloid differentiation.
|
Concept
|
Fingolimod Hydrochloride
|
Concept
|
Dasatinib
|
Concept
|
Myeloid Cell Leukemia Sequence 1 Protein
|
Concept
|
In Vitro Techniques
|
Concept
|
Imatinib Mesylate
|
Concept
|
Inositol Polyphosphate 5-Phosphatases
|
Concept
|
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
|
Academic Article
|
Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions.
|
Academic Article
|
TGF-beta utilizes SMAD3 to inhibit CD16-mediated IFN-gamma production and antibody-dependent cellular cytotoxicity in human NK cells.
|
Academic Article
|
miR-155 regulates IFN-? production in natural killer cells.
|
Academic Article
|
CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets.
|
Academic Article
|
PTEN is a negative regulator of NK cell cytolytic function.
|
Academic Article
|
NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human.
|
Academic Article
|
Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress.
|
Academic Article
|
The transcription Factor AHR prevents the differentiation of a stage 3 innate lymphoid cell subset to natural killer cells.
|
Academic Article
|
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein.
|
Academic Article
|
Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay.
|
Academic Article
|
Axl/Gas6 pathway positively regulates FLT3 activation in human natural killer cell development.
|
Academic Article
|
Efficient infection of human natural killer cells with an EBV/retroviral hybrid vector.
|
Academic Article
|
Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells.
|
Academic Article
|
The PP2A inhibitor SET regulates natural killer cell IFN-gamma production.
|
Academic Article
|
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
|
Academic Article
|
The PP2A inhibitor SET regulates granzyme B expression in human natural killer cells.
|
Academic Article
|
CD94 defines phenotypically and functionally distinct mouse NK cell subsets.
|
Academic Article
|
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.
|
Academic Article
|
Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells.
|
Academic Article
|
Differential expression of SHIP1 in CD56bright and CD56dim NK cells provides a molecular basis for distinct functional responses to monokine costimulation.
|
Academic Article
|
Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells.
|
Academic Article
|
CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody.
|
Academic Article
|
Comparative assessment of clinically utilized CD20-directed antibodies in chronic lymphocytic leukemia cells reveals divergent NK cell, monocyte, and macrophage properties.
|
Academic Article
|
Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice.
|
Academic Article
|
TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia.
|
Academic Article
|
FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways.
|
Academic Article
|
Transcriptional control of human T-BET expression: the role of Sp1.
|
Academic Article
|
Src homology 2-containing inositol 5'-phosphatase 1 negatively regulates IFN-gamma production by natural killer cells stimulated with antibody-coated tumor cells and interleukin-12.
|
Academic Article
|
BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia.
|
Academic Article
|
The Axl/Gas6 pathway is required for optimal cytokine signaling during human natural killer cell development.
|