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The broad focus of our lab is to investigate the dynamic, transient and lower-abundance organelle associated actin filaments in regulating inter-organelle communication and overall cellular homeostasis. Specifically, we focus on two dynamic pools of actin filaments, one assembled on the Endoplasmic Reticulum and the other on mitochondria and ask mechanistic questions to understand how these under-appreciated filament populations regulate cellular physiology and pathology.
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