Item Type | Name |
Concept
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Adult
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Concept
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Amino Acid Sequence
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Concept
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Animals
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Concept
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Artificial Intelligence
|
Concept
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Base Sequence
|
Concept
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Cattle
|
Concept
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Cell Aggregation
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Concept
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Cell Communication
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Concept
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Cell Cycle
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Concept
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Cell Differentiation
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Concept
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Cell Division
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Concept
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Cell Extracts
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Concept
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Cell Line
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Concept
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Cell Line, Transformed
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Concept
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Cell Nucleus
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Concept
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Cell Survival
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Concept
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Cell Transformation, Neoplastic
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Concept
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Cell-Free System
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Concept
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Cells, Cultured
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Concept
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Chickens
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Concept
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Child
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Concept
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Clone Cells
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Concept
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Cricetulus
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Concept
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Dendritic Cells
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Concept
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Eukaryotic Cells
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Concept
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Genes, Lethal
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Concept
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Cricetinae
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Concept
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HeLa Cells
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Concept
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Humans
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Concept
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Image Interpretation, Computer-Assisted
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Concept
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Isotope Labeling
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Concept
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Laboratories
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Concept
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Liver Neoplasms
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Concept
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Luminescent Proteins
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Concept
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Lung Neoplasms
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Concept
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Lymphocytes
|
Concept
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Lymphocytic Choriomeningitis
|
Concept
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Lymphocytic choriomeningitis virus
|
Concept
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Lysophospholipids
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Concept
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Mammals
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Concept
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Molecular Sequence Data
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Concept
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Terminology as Topic
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Concept
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Periodicals as Topic
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Concept
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DNA Ligases
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Concept
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Simian virus 40
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Concept
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Tumor Cells, Cultured
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Concept
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Xenopus laevis
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Concept
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Resting Phase, Cell Cycle
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Concept
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CHO Cells
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Concept
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Mice, SCID
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Concept
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Mice, Inbred NOD
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Concept
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Cell Death
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Concept
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Rats, Sprague-Dawley
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Concept
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Mice, Knockout
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Concept
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Spodoptera
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Concept
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CD8-Positive T-Lymphocytes
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Concept
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Linear Energy Transfer
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Concept
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Cell Cycle Proteins
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Concept
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Proliferating Cell Nuclear Antigen
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Concept
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Cell Culture Techniques
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Concept
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Information Dissemination
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Concept
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Endothelial Cells
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Concept
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DNA-(Apurinic or Apyrimidinic Site) Lyase
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Concept
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SKP Cullin F-Box Protein Ligases
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Concept
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HCT116 Cells
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Concept
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Cell Line, Tumor
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Concept
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Cell Growth Processes
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Concept
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Cell Proliferation
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Concept
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Mice
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Concept
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Rats
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Concept
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Young Adult
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Concept
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HEK293 Cells
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Concept
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Cell Cycle Checkpoints
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Concept
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G2 Phase Cell Cycle Checkpoints
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Concept
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M Phase Cell Cycle Checkpoints
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Concept
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G1 Phase Cell Cycle Checkpoints
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Concept
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Sf9 Cells
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Academic Article
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Effects of hyperthermia on p53 protein expression and activity.
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Academic Article
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Targeting angiogenic processes by combination low-dose paclitaxel and radiation therapy.
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Concept
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A549 Cells
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Concept
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DNA Ligase ATP
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Academic Article
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Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing.
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Academic Article
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hTERT associates with human telomeres and enhances genomic stability and DNA repair.
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Academic Article
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DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG2 cell line.
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Academic Article
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CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity.
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Academic Article
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Biochemical evidence for Ku-independent backup pathways of NHEJ.
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Academic Article
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Computational Methods for analysis of foci: validation for radiation-induced gamma-H2AX foci in human cells.
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Academic Article
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Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
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Academic Article
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Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.
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Academic Article
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Interferon alpha 2a down-regulates VEGF expression through PI3 kinase and MAP kinase signaling pathways.
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Academic Article
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Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation.
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Academic Article
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Checkpoint abrogation in G2 compromises repair of chromosomal breaks in ataxia telangiectasia cells.
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Academic Article
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ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining.
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Academic Article
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Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks.
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Academic Article
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Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks.
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Academic Article
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DNA damage checkpoint control in cells exposed to ionizing radiation.
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Academic Article
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Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
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Academic Article
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DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
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Academic Article
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Reduction in p48-ISGFgamma levels confers resistance to interferon-alpha2a in MHCC97 cells.
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Academic Article
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Backup pathways of NHEJ are suppressed by DNA-PK.
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Academic Article
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Initial characterization of a low-molecular-weight factor enhancing the checkpoint response.
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Academic Article
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In vitro rejoining of double strand breaks in genomic DNA.
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Academic Article
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Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons.
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Academic Article
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DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice.
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Academic Article
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Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.
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Academic Article
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The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killing.
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Academic Article
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Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.
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Academic Article
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The impact of serotonin on the development of bystander damage assessed by ?-H2AX foci analysis.
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Academic Article
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The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
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Academic Article
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SCFSKP2 regulates APC/CCDH1-mediated degradation of CTIP to adjust DNA-end resection in G2-phase.
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Academic Article
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Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
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Academic Article
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PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
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Academic Article
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DEFINED BIOLOGICAL MODELS OF HIGH-LET RADIATION LESIONS.
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Academic Article
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BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
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Academic Article
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Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response.
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Academic Article
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The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR.
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Academic Article
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Effects of chromatin decondensation on alternative NHEJ.
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Academic Article
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Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment.
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Academic Article
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Abdominopelvic 1.5-T and 3.0-T MR Imaging in Healthy Volunteers: Relationship to Formation of DNA Double-Strand Breaks.
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Academic Article
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Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells.
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Academic Article
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Intercellular communication of DNA damage and oxidative status underpin bystander effects.
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Academic Article
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An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.
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Academic Article
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Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative status.
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Academic Article
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Low levels of DNA ligases III and IV sufficient for effective NHEJ.
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Academic Article
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Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.
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Academic Article
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Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.
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Academic Article
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Marked dependence on growth state of backup pathways of NHEJ.
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Academic Article
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Histone H1 functions as a stimulatory factor in backup pathways of NHEJ.
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Academic Article
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Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
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Academic Article
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Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons.
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Academic Article
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DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.
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Academic Article
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Strong Shift to ATR-Dependent Regulation of the G2-Checkpoint after Exposure to High-LET Radiation.
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Academic Article
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DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.
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Academic Article
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Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions.
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Academic Article
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Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles.
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Academic Article
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Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair.
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Academic Article
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Loss of TGF? signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types.
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Academic Article
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PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.
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Academic Article
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ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
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Academic Article
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Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors.
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Academic Article
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Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cells.
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Academic Article
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Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.
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Academic Article
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Break-induced replication repair of damaged forks induces genomic duplications in human cells.
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Academic Article
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Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.
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Academic Article
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Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
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Academic Article
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Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining.
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Academic Article
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Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.
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Academic Article
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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.
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Academic Article
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Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
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Academic Article
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Dependence of adaptive response and its bystander transmission on the genetic background of tested cells.
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Academic Article
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A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks.
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Academic Article
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Analysis of inhibition of DNA replication in irradiated cells using the SV40 based in vitro assay of DNA replication.
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Academic Article
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Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside-Nucleoside Analogue Radiosensitization.
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Academic Article
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Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.
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Academic Article
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Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence.
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Academic Article
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Extensive repair of DNA double-strand breaks in cells deficient in the DNA-PK-dependent pathway of NHEJ after exclusion of heat-labile sites.
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Academic Article
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Application of alkaline sucrose gradient centrifugation in the analysis of DNA replication after DNA damage.
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Academic Article
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The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation.
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Academic Article
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Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.
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Academic Article
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Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.
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Academic Article
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Inhibition of B-NHEJ in plateau-phase cells is not a direct consequence of suppressed growth factor signaling.
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Academic Article
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Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.
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Academic Article
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New partners for Chk1.
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Academic Article
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Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.
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Academic Article
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"Praising What Is Lost. . .
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Academic Article
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Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell lines.
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Academic Article
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Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.
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Academic Article
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The anatomy and cell cycle evolution of DNA damage signaling and repair foci.
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Academic Article
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A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
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Academic Article
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Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion.
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Academic Article
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Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors.
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Academic Article
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Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages.
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Academic Article
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Plasmid-based assays for DNA end-joining in vitro.
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Academic Article
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Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation.
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Academic Article
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The contribution of thermally labile sugar lesions to DNA double-strand break formation in cells grown in the presence of BrdU.
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Academic Article
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Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).
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Academic Article
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Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III.
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Academic Article
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Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.
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Academic Article
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Analysis of inhibition of DNA replication in irradiated cells using the SV40-based in vitro assay of DNA replication.
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Academic Article
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G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells.
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Academic Article
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Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
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Academic Article
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In vitro rejoining of double-strand breaks in genomic DNA.
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Academic Article
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An ATM-independent S-phase checkpoint response involves CHK1 pathway.
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Academic Article
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Cell line specific modulation of connexin43 expression after exposure to ionizing radiation.
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Academic Article
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DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation.
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Academic Article
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DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates.
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Academic Article
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Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer.
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Academic Article
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Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
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Academic Article
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Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination.
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Academic Article
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Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
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Academic Article
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Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
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Academic Article
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Enhanced use of backup pathways of NHEJ in G2 in Chinese hamster mutant cells with defects in the classical pathway of NHEJ.
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Academic Article
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Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells.
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Academic Article
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When a duck is not a duck; a new interdisciplinary synthesis for environmental radiation protection.
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Academic Article
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The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
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Academic Article
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Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.
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Academic Article
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Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response.
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Academic Article
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Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Pol? inhibition.
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Academic Article
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NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells.
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