| Item Type | Name |
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Concept
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Adult
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Concept
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Amino Acid Sequence
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Concept
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Animals
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Concept
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Artificial Intelligence
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Concept
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Avian Sarcoma Viruses
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Concept
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B-Lymphocytes
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Concept
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Base Sequence
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Concept
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Cattle
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Concept
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Cell Aggregation
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Concept
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Cell Communication
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Concept
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Cell Cycle
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Concept
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Cell Differentiation
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Concept
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Cell Division
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Concept
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Cell Extracts
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Concept
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Cell Fusion
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Concept
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Cell Line
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Concept
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Cell Line, Transformed
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Concept
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Cell Nucleolus
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Concept
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Cell Nucleus
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Concept
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Cell Survival
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Concept
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Cell Transformation, Neoplastic
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Concept
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Cell-Free System
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Concept
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Cells, Cultured
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Concept
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Chickens
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Concept
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Child
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Concept
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Clone Cells
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Concept
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Cricetulus
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Concept
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Cytomegalovirus
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Concept
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Dendritic Cells
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Concept
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Epithelial Cells
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Concept
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Eukaryotic Cells
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Concept
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Genes, Lethal
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Concept
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Genetic Vectors
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Concept
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Cricetinae
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Concept
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HeLa Cells
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Concept
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Humans
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Concept
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Hybrid Cells
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Concept
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Image Interpretation, Computer-Assisted
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Concept
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Isotope Labeling
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Concept
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Laboratories
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Concept
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Lasers
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Concept
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Liver Neoplasms
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Concept
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Luminescent Proteins
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Concept
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Lung
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Concept
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Lung Neoplasms
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Concept
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Lymphocytes
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Concept
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Lymphocytic Choriomeningitis
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Concept
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Lymphocytic choriomeningitis virus
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Concept
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Lysophospholipids
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Concept
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Mammals
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Concept
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Mammary Tumor Virus, Mouse
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Concept
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Mice, Inbred C3H
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Concept
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Middle Aged
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Concept
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Molecular Sequence Data
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Concept
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Terminology as Topic
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Concept
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Parainfluenza Virus 1, Human
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Concept
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Periodicals as Topic
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Concept
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DNA Ligases
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Schizosaccharomyces
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Concept
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Simian virus 40
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Concept
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T-Lymphocytes
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Concept
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Tumor Cells, Cultured
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Concept
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Xenopus laevis
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Concept
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Gene Rearrangement, T-Lymphocyte
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Concept
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Resting Phase, Cell Cycle
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Concept
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CHO Cells
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Concept
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3T3 Cells
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Concept
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Mice, SCID
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Concept
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Mice, Inbred NOD
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Concept
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Cell Death
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Concept
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Rats, Sprague-Dawley
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Concept
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Mice, Knockout
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Concept
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Spodoptera
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Concept
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CD8-Positive T-Lymphocytes
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Concept
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Linear Energy Transfer
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Concept
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Cell Cycle Proteins
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Concept
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Proliferating Cell Nuclear Antigen
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Concept
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Cells, Immobilized
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Concept
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Cell Culture Techniques
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Concept
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HT29 Cells
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Concept
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Information Dissemination
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Concept
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Endothelial Cells
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Concept
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DNA-(Apurinic or Apyrimidinic Site) Lyase
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Concept
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SKP Cullin F-Box Protein Ligases
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Concept
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HCT116 Cells
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Concept
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Cell Line, Tumor
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Concept
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Cell Growth Processes
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Concept
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Cell Proliferation
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Concept
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T-Lymphocytes, Regulatory
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Concept
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Mice
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Concept
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Rats
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Concept
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Young Adult
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Concept
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HEK293 Cells
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Concept
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Cell Cycle Checkpoints
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Concept
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G2 Phase Cell Cycle Checkpoints
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Concept
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M Phase Cell Cycle Checkpoints
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Concept
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G1 Phase Cell Cycle Checkpoints
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Concept
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Sf9 Cells
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Academic Article
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Effects of hyperthermia on p53 protein expression and activity.
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Academic Article
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Targeting angiogenic processes by combination low-dose paclitaxel and radiation therapy.
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Concept
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A549 Cells
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Concept
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DNA Ligase ATP
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Academic Article
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Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing.
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Academic Article
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hTERT associates with human telomeres and enhances genomic stability and DNA repair.
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Academic Article
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DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG2 cell line.
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Academic Article
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CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity.
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Academic Article
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Biochemical evidence for Ku-independent backup pathways of NHEJ.
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Academic Article
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Computational Methods for analysis of foci: validation for radiation-induced gamma-H2AX foci in human cells.
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Academic Article
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Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
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Academic Article
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Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.
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Academic Article
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Interferon alpha 2a down-regulates VEGF expression through PI3 kinase and MAP kinase signaling pathways.
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Academic Article
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Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation.
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Academic Article
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Checkpoint abrogation in G2 compromises repair of chromosomal breaks in ataxia telangiectasia cells.
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Academic Article
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ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining.
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Academic Article
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Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks.
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Academic Article
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Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks.
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Academic Article
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DNA damage checkpoint control in cells exposed to ionizing radiation.
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Academic Article
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Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
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Academic Article
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DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
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Academic Article
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Reduction in p48-ISGFgamma levels confers resistance to interferon-alpha2a in MHCC97 cells.
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Academic Article
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Backup pathways of NHEJ are suppressed by DNA-PK.
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Academic Article
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Initial characterization of a low-molecular-weight factor enhancing the checkpoint response.
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Academic Article
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In vitro rejoining of double strand breaks in genomic DNA.
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Academic Article
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Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons.
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Academic Article
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DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice.
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Academic Article
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Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.
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Academic Article
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The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killing.
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Academic Article
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Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.
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Academic Article
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The impact of serotonin on the development of bystander damage assessed by ?-H2AX foci analysis.
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Academic Article
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The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
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Academic Article
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SCFSKP2 regulates APC/CCDH1-mediated degradation of CTIP to adjust DNA-end resection in G2-phase.
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Academic Article
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Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
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Academic Article
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PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
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Academic Article
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DEFINED BIOLOGICAL MODELS OF HIGH-LET RADIATION LESIONS.
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Academic Article
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BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
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Academic Article
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Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response.
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Academic Article
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The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR.
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Academic Article
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Effects of chromatin decondensation on alternative NHEJ.
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Academic Article
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Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment.
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Academic Article
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Abdominopelvic 1.5-T and 3.0-T MR Imaging in Healthy Volunteers: Relationship to Formation of DNA Double-Strand Breaks.
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Academic Article
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Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells.
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Academic Article
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Intercellular communication of DNA damage and oxidative status underpin bystander effects.
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Academic Article
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An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.
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Academic Article
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Bystander effects as manifestation of intercellular communication of DNA damage and of the cellular oxidative status.
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Academic Article
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Low levels of DNA ligases III and IV sufficient for effective NHEJ.
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Academic Article
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Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.
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Academic Article
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Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.
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Academic Article
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Marked dependence on growth state of backup pathways of NHEJ.
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Academic Article
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Histone H1 functions as a stimulatory factor in backup pathways of NHEJ.
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Academic Article
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Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
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Academic Article
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Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons.
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Academic Article
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DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.
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Academic Article
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Strong Shift to ATR-Dependent Regulation of the G2-Checkpoint after Exposure to High-LET Radiation.
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Academic Article
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DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.
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Academic Article
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Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions.
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Academic Article
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Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles.
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Academic Article
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Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair.
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Academic Article
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Loss of TGF? signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types.
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Academic Article
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PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.
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Academic Article
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ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
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Academic Article
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Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors.
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Academic Article
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Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cells.
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Academic Article
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Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.
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Academic Article
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Break-induced replication repair of damaged forks induces genomic duplications in human cells.
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Academic Article
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Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.
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Academic Article
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Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
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Academic Article
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Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining.
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Academic Article
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Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.
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Academic Article
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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.
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Academic Article
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Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
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Academic Article
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Dependence of adaptive response and its bystander transmission on the genetic background of tested cells.
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Academic Article
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A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks.
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Academic Article
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Analysis of inhibition of DNA replication in irradiated cells using the SV40 based in vitro assay of DNA replication.
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Academic Article
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Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside-Nucleoside Analogue Radiosensitization.
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Academic Article
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Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.
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Academic Article
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Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence.
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Academic Article
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Extensive repair of DNA double-strand breaks in cells deficient in the DNA-PK-dependent pathway of NHEJ after exclusion of heat-labile sites.
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Academic Article
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Application of alkaline sucrose gradient centrifugation in the analysis of DNA replication after DNA damage.
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Academic Article
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The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation.
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Academic Article
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Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.
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Academic Article
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Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.
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Academic Article
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Inhibition of B-NHEJ in plateau-phase cells is not a direct consequence of suppressed growth factor signaling.
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Academic Article
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Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.
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Academic Article
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New partners for Chk1.
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Academic Article
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Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.
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Academic Article
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"Praising What Is Lost. . .
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Academic Article
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Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell lines.
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Academic Article
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Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.
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Academic Article
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The anatomy and cell cycle evolution of DNA damage signaling and repair foci.
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Academic Article
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A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
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Academic Article
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Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion.
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Academic Article
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Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors.
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Academic Article
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Regulation of ABCA1-mediated cholesterol efflux by sphingosine-1-phosphate signaling in macrophages.
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Academic Article
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Plasmid-based assays for DNA end-joining in vitro.
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Academic Article
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Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation.
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Academic Article
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The contribution of thermally labile sugar lesions to DNA double-strand break formation in cells grown in the presence of BrdU.
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Academic Article
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Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).
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Academic Article
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Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III.
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Academic Article
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Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.
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Academic Article
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Analysis of inhibition of DNA replication in irradiated cells using the SV40-based in vitro assay of DNA replication.
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Academic Article
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G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells.
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Academic Article
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Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
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Academic Article
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In vitro rejoining of double-strand breaks in genomic DNA.
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Academic Article
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An ATM-independent S-phase checkpoint response involves CHK1 pathway.
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Academic Article
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Cell line specific modulation of connexin43 expression after exposure to ionizing radiation.
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Academic Article
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DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation.
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Academic Article
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DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates.
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Academic Article
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Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer.
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Academic Article
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Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
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Academic Article
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Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination.
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Academic Article
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Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
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Academic Article
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Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
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Academic Article
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Enhanced use of backup pathways of NHEJ in G2 in Chinese hamster mutant cells with defects in the classical pathway of NHEJ.
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Academic Article
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Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells.
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Academic Article
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When a duck is not a duck; a new interdisciplinary synthesis for environmental radiation protection.
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Academic Article
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The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
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Academic Article
|
Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.
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Academic Article
|
Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response.
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Academic Article
|
Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Pol? inhibition.
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Academic Article
|
NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells.
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Academic Article
|
Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group.
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Academic Article
|
Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
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Academic Article
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DNA-PK-independent rejoining of DNA double-strand breaks in human cell extracts in vitro.
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Academic Article
|
Results of a pilot study involving the use of an antisense oligodeoxynucleotide directed against the insulin-like growth factor type I receptor in malignant astrocytomas.
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Academic Article
|
Mechanism of radiosensitization by halogenated pyrimidines: the contribution of excess DNA and chromosome damage in BrdU radiosensitization may be minimal in plateau-phase cells.
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Academic Article
|
Enhancement of adriamycin-induced killing after delayed plating of plateau-phase V79-cells.
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Academic Article
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Mitotic metaphase cells from different cell lines cause different levels of expression of the alpha-form of interphase chromosome breaks in irradiated CHO cells.
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Academic Article
|
Measurement of DNA double-strand breaks in CHO cells at various stages of the cell cycle using pulsed field gel electrophoresis: calibration by means of 125I decay.
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Academic Article
|
In vitro rejoining of double-strand breaks in genomic DNA.
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Academic Article
|
Effects of the nucleoside analogues alpha-ara A, beta-ara A and beta-ara C on cell growth and repair of both potentially lethal damage and DNA double strand breaks in mammalian cells in culture.
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Academic Article
|
Linear DNA elution dose response curves obtained in CHO cells with non-unwinding filter elution after appropriate selection of the lysis conditions.
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Academic Article
|
Regulation of DNA replication in irradiated cells by trans-acting factors.
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Academic Article
|
Effects of ionizing radiation on cyclin expression in HeLa cells.
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Academic Article
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Cyclin B expression in HeLa cells during the G2 block induced by ionizing radiation.
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Academic Article
|
Effects of aphidicolin on the repair and fixation of potentially lethal damage sensitive to beta-araA.
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Academic Article
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Effects of beta-arabinofuranosyladenine on potentially lethal damage induced in plateau phase mammalian cells exposed to U.V.-light.
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Academic Article
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Induction and repair of DNA double strand breaks in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc.
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Academic Article
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Analysis of inhibition of DNA replication in irradiated cells using the SV40-based in vitro assay of DNA replication.
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Academic Article
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Reduction by caffeine of adriamycin-induced cell killing and DNA damage in Chinese hamster cells: correlation with modulation in intracellular adriamycin content.
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Academic Article
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Effects of adenosine deaminase inhibitor 2'-deoxycoformycin on the repair and expression of potentially lethal damage sensitive to beta-araA.
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Academic Article
|
Effects of hyperthermia on the repair of radiation-induced DNA single- and double-strand breaks in DNA double-strand break repair-deficient and repair-proficient cell lines.
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Academic Article
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Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays.
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Academic Article
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Increased frequency of formation of interphase ring-chromosomes in radiosensitive irs-1 cells exposed to X-rays.
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Academic Article
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Evidence for an S-phase checkpoint regulating DNA replication after heat shock: a review.
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Academic Article
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Induction by H2O2 of DNA and interphase chromosome damage in plateau-phase Chinese hamster ovary cells.
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Academic Article
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Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts.
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Academic Article
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Quantitative aspects of repair of potentially lethal damage in mammalian cells.
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Academic Article
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Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: comparison with fixation of PLD.
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Academic Article
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Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.
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Academic Article
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Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts.
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Academic Article
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Ionizing radiation induces two forms of interphase chromosome breaks in Chinese hamster ovary cells that rejoin with different kinetics and show different sensitivity to treatment in hypertonic medium or beta-araA.
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Academic Article
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Effects of hyperthermia on chromatin condensation and nucleoli disintegration as visualized by induction of premature chromosome condensation in interphase mammalian cells.
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Academic Article
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Investigation of bystander effects in hybrid cells by means of cell fusion and premature chromosome condensation induction.
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Academic Article
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Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on repair of DNA breaks, interphase chromatin breaks, and potentially lethal damage in plateau-phase CHO cells.
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Academic Article
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DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus.
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Academic Article
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Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining.
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Academic Article
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Radiation-induced potentially lethal damage: DNA lesions susceptible to fixation.
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Academic Article
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Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on cell killing and interphase chromosome breakage in radiation-sensitive cells.
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Academic Article
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Effect of ionizing radiation on the expression of chloramphenicol acetyltransferase gene under the control of commonly used constitutive or inducible promoters.
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Academic Article
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Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing.
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Academic Article
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Hyperthermia does not affect rejoining of DNA double-strand breaks in a cell-free assay.
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Academic Article
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Repair of potentially lethal damage in unfed plateau phase cultures of Ehrlich ascites tumour cells. II. Monolayer cultures.
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Academic Article
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Mechanisms of DNA double strand break repair and chromosome aberration formation.
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Academic Article
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Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.
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Academic Article
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Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis.
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Academic Article
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Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants.
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Academic Article
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Application of non-hypoxic cell sensitizers in radiobiology and radiotherapy: rationale and future prospects.
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Academic Article
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Radioresistance induced in rat embryo cells by transfection with the oncogenes H-ras plus v-myc is cell cycle dependent and maximal during S and G2.
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Academic Article
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Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage.
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Academic Article
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Mitosis-promoting factor activity of inducer mitotic cells may affect radiation yield of interphase chromosome breaks in the premature chromosome condensation assay.
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Academic Article
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Inactivation of Ehrlich ascites tumor cells by heavy ions.
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Academic Article
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Sensitization to hyperthermia by 3,3'-dipentyloxacarbocyanine iodide: a positive correlation with DNA damage and negative correlations with altered cell morphology, oxygen consumption inhibition, and reduced ATP levels.
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Academic Article
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Mechanism of radiosensitization by halogenated pyrimidines: bromodeoxyuridine and beta-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateau-phase Chinese hamster ovary cells.
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Academic Article
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The level of induced DNA double-strand breaks does not correlate with cell killing in X-irradiated mitotic and G1-phase CHO cells.
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Academic Article
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The influence of PLD repair on the induction frequency of 6-thioguanine resistant mutants in Ehrlich ascites tumour cells after exposure to X-rays and ultraviolet light.
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Academic Article
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Effects of beta-arabinofuranosyladenine on the growth and repair of potentially lethal damage in Ehrilch ascites tumor cells.
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Academic Article
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Size distribution of DNA molecules recovered from non-denaturing filter elution.
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Academic Article
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Evidence for induction and repair of potentially lethal damage in plateau-phase V79 cells after exposure to adriamycin. The importance of removal of adriamycin released from the cells during the post-treatment incubation period.
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Academic Article
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Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams.
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Academic Article
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Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.
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Academic Article
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Hypertonic treatment does not affect the radiation yield of interphase chromosome breaks in DNA double-strand break repair-deficient xrs-5 cells.
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Academic Article
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The importance of G1/S-border and mitosis in the fixation of potentially lethal damage.
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Academic Article
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Repair of DNA double-strand breaks and radiosensitivity to killing in an isogenic group of p53 mutant cell lines.
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Academic Article
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Evidence that progression of cells into S-phase is not a prerequisite for recovery between split doses of U.V.-light in synchronized and plateau phase cultures of Ehrlich ascites tumour cells.
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Academic Article
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RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate.
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Academic Article
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Evidence for differences among the sectors of potentially lethal damage expressed by hypertonic treatment in plateau-phase V79 cells after exposure to neutrons or gamma rays: the importance of distinction between alpha and beta-PLD forms.
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Academic Article
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Replication protein A as a potential regulator of DNA replication in cells exposed to hyperthermia.
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Academic Article
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125IdUrd-induced chromosome fragments, assayed by premature chromosome condensation, and DNA double-strand breaks have similar repair kinetics in G1-phase CHO-cells.
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Academic Article
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Aphidicolin promotes repair of potentially lethal damage in irradiated mammalian cells synchronized in S-phase.
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Academic Article
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Down-regulation of DNA replication in extracts of camptothecin-treated cells: activation of an S-phase checkpoint?
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Academic Article
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Cell cycle regulation in irradiated and nonirradiated cells.
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Academic Article
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Reversing regulatory safeguards: Targeting the ATR pathway to overcome PARP inhibitor resistance.
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Academic Article
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Effect of sodium chloride concentration on adriamycin and N-trifluoroacetyladriamycin-14-valerate (AD32)-induced cell killing and DNA damage in Chinese hamster V79 cells.
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Academic Article
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Technical note: comparison of yields and repair kinetics of interphase chromosome breaks visualized by Sendai-virus or PEG-mediated cell fusion in irradiated CHO cells.
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Academic Article
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Modulation of adriamycin and N-trifluoroacetyladriamycin-14-valerate induced effects on cell cycle traverse and cytotoxicity in P388 mouse leukemia cells by caffeine and the calmodulin inhibitor trifluoperazine.
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Academic Article
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The shape of DNA elution dose-response curves under non-denaturing conditions: the contribution of the degree of chromatin condensation.
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Academic Article
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Conditions supporting repair of potentially lethal damage cause a significant reduction of ultraviolet light-induced division delay in synchronized and plateau-phase Ehrlich ascites tumor cells.
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Academic Article
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Differential reduction by caffeine of adriamycin induced cell killing and cell cycle delays in Chinese hamster V79 cells.
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Academic Article
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Induction of DNA double-strand breaks by restriction enzymes in X-ray-sensitive mutant Chinese hamster ovary cells measured by pulsed-field gel electrophoresis.
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Academic Article
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Comparison of DNA double-strand break rejoining as measured by pulsed field gel electrophoresis, neutral sucrose gradient centrifugation and non-unwinding filter elution in irradiated plateau-phase CHO cells.
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Academic Article
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Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: implications for the mechanism of radiosensitivity.
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Academic Article
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Regulation of dna replication after heat shock by replication protein a-nucleolin interactions.
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Academic Article
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Effects of aphidicolin on cell proliferation, repair of potentially lethal damage and repair of DNA strand breaks in Ehrlich ascites tumour cells exposed to X-rays.
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Academic Article
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Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant.
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Academic Article
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The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway.
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Academic Article
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Hypertonic treatment during premature chromosome condensation allows visualization of interphase chromosome breaks repaired with fast kinetics in irradiated CHO cells.
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Academic Article
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Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc.
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Academic Article
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In vitro rejoining of double-strand breaks in cellular DNA by factors present in extracts of HeLa cells.
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Academic Article
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The mutagenicity of alpha particles in Ehrlich ascites tumor cells.
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Academic Article
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Apoptosis as a predictor of paclitaxel-induced radiosensitization in human tumor cell lines.
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Academic Article
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Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity.
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Academic Article
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Modifications in repair and expression of potentially lethal damage (alpha-PLD) as measured by delayed plating or treatment with beta-araA in plateau-phase Ehrlich ascites tumor cells after exposure to charged particles of various specific energies.
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Academic Article
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Effect of arabinofuranosyladenine on radiation-induced chromosome damage in plateau-phase CHO cells measured by premature chromosome condensation: implications for repair and fixation of alpha-PLD.
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Academic Article
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Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines.
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Academic Article
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Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics.
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Academic Article
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Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient.
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Academic Article
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Biological dosimetry of absorbed radiation by C-banding of interphase chromosomes in peripheral blood lymphocytes.
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Academic Article
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Effects of caffeine on X-irradiated synchronous, asynchronous and plateau phase mouse ascites cells: the importance of progression through the cell cycle for caffeine enhancement of killing.
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Academic Article
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Differences in inhibition by beta-arabinofuranosyladenine (araA) of radiation induced DNA damage repair in exponentially growing and plateau-phase CHO-cells.
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Academic Article
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Evidence that repair and expression of potentially lethal damage cause the variations in cell survival after X irradiation observed through the cell cycle in Ehrlich ascites tumor cells.
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Academic Article
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Repair of potentially lethal damage in unfed plateau phase cultures of Ehrlich ascites tumour cells. I. Suspension cultures.
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Academic Article
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Overexpression of insulin-like growth factor (IGF)-I receptor enhances inhibition of DNA replication in mouse cells exposed to x-rays.
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Academic Article
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Persistent inhibition of DNA synthesis after radiation exposure in four clones obtained from rat embryo fibroblasts by transfection with the oncogenes H-ras plus v-myc.
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Academic Article
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The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells.
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Academic Article
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Inhibition of DNA replication by tirapazamine.
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Academic Article
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A DNA double-strand break repair-deficient mutant of CHO cells shows reduced radiosensitization after exposure to hyperthermic temperatures in the plateau phase of growth.
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Academic Article
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In vitro rejoining of DNA double strand breaks: a comparison of genomic-DNA with plasmid-DNA-based assays.
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Academic Article
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Possible importance of PLD repair in the modulation of BrdUrd and IdUrd-mediated radiosensitization in plateau-phase C3H10T1/2 mouse embryo cells.
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Academic Article
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Characterization and properties of repair of potentially lethal damage as measured with the help of beta-arabinofuranosyladenine in plateau-phase EAT cells.
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Academic Article
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Effects of 5'-iododeoxyuridine on the repair of radiation induced potentially lethal damage interphase chromatin breaks and DNA double strand breaks in Chinese hamster ovary cells.
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Academic Article
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Radiosensitive xrs-5 and parental CHO cells show identical DNA neutral filter elution dose-response: implications for a relationship between cell radiosensitivity and induction of DNA double-strand breaks.
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Academic Article
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Possible correlations between cell killing, chromosome damage and DNA repair after X-irradiation.
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Academic Article
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Variation through the cell cycle in the dose-response of DNA neutral filter elution in X-irradiated synchronous CHO-cells.
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Academic Article
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Kinetics of DNA double-strand break repair throughout the cell cycle as assayed by pulsed field gel electrophoresis in CHO cells.
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Academic Article
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Radiation-sensitive irs mutants rejoin DNA double-strand breaks with efficiency similar to that of parental V79 cells but show altered response to radiation-induced G2 delay.
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Academic Article
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Persistent inhibition of DNA synthesis in irradiated rat embryo fibroblasts expressing the oncogenes H-ras plus v-myc derives from inhibition of replicon initiation and is mitigated by staurosporine.
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Academic Article
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A cell-free assay using cytoplasmic cell extracts to study rejoining of radiation-induced DNA double-strand breaks in human cell nuclei.
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Academic Article
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Repair and fixation of potentially lethal damage (PLD) as demonstrated by delayed plating or incubation with araA in contact inhibited refed plateau-phase C3H mouse embryo 10 T1/2 cells grown in the presence of BrdUrd.
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Academic Article
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Arrest of irradiated G1, S, or G2 cells at mitosis using nocodazole promotes repair of potentially lethal damage.
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Academic Article
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Dose-rate effect on radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line.
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Academic Article
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Independent forms of potentially lethal damage fixed in plateau-phase Chinese hamster cells by postirradiation treatment in hypertonic salt solution or araA.
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Academic Article
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Evidence for factors modulating radiation-induced G2-delay: potential application as radioprotectors.
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Academic Article
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Evidence for similarities between radiation damage expressed by beta-araA and damage involved in the interaction effect observed after exposure of V79 cells to mixed neutrons and gamma radiation.
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Academic Article
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Evidence for the induction of two types of potentially lethal damage after exposure of plateau phase Chinese hamster V79 cells to gamma-rays.
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Academic Article
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Evidence for activities inhibiting in trans initiation of DNA replication in extract prepared from irradiated cells.
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Academic Article
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The influence of conditions affecting repair and fixation of potentially lethal damage on the induction of 6-thioguanine resistance after exposure of mammalian cells to X-rays.
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Academic Article
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In vitro rejoining of double strand breaks induced in cellular DNA by bleomycin and restriction endonucleases.
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Academic Article
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Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc.
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Academic Article
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Evidence for reduced capacity for damage accumulation and repair in plateau-phase C3H 10T1/2 cells following multiple-dose irradiation with gamma rays.
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