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Iliakis, George
One or more keywords matched the following items that are connected to Iliakis, George
Item TypeName
Concept Acute Disease
Concept Adenosine Triphosphate
Concept Alkaloids
Concept Amino Acid Sequence
Concept Androstadienes
Concept Antibodies, Monoclonal
Concept Antineoplastic Agents, Phytogenic
Concept Ataxia Telangiectasia
Concept Azacitidine
Concept Base Sequence
Concept Benzamides
Concept Benzimidazoles
Concept Binding, Competitive
Concept Biological Transport
Concept Biophysics
Concept Bromodeoxyuridine
Concept Caffeine
Concept Calcium-Binding Proteins
Concept Camptothecin
Concept Cattle
Concept Cell Aggregation
Concept Cell Cycle
Concept Cell Differentiation
Concept Cell Division
Concept Cell Line, Transformed
Concept Cell Nucleus
Concept Cell-Free System
Concept Centrifugation, Density Gradient
Concept Centromere
Concept Chemotaxis
Concept Chickens
Concept Cholesterol
Concept Chromates
Concept Chromatids
Concept Chromatin
Concept Chromosome Aberrations
Concept Chromosomes
Concept Chromosomes, Human
Concept Combined Modality Therapy
Concept Cricetulus
Concept Diabetes Mellitus, Type 1
Concept DNA Repair
Concept DNA Replication
Concept DNA Helicases
Concept DNA, Circular
Concept DNA, Superhelical
Concept Dose-Response Relationship, Radiation
Concept Electrophoresis
Concept Electrophoresis, Agar Gel
Concept Enzyme Activation
Concept Fever
Concept Flow Cytometry
Concept Cricetinae
Concept Hot Temperature
Concept HeLa Cells
Concept Carcinoma, Hepatocellular
Concept Histones
Concept Humans
Concept Image Interpretation, Computer-Assisted
Concept Immunohistochemistry
Concept Kinetics
Concept Lymphocytes
Concept Lymphocytic Choriomeningitis
Concept Lymphocytic choriomeningitis virus
Concept Mammals
Concept Metaphase
Concept Mitochondria
Concept Mitosis
Concept Nucleic Acid Denaturation
Concept Oxazoles
Concept Periodicals as Topic
Concept Phosphorylation
Concept Poly(ADP-ribose) Polymerases
Concept Promoter Regions, Genetic
Concept Protein Binding
Concept Protein Conformation
Concept Radiation Genetics
Concept Radiobiology
Concept Serotonin
Concept Sphingosine
Concept Tamoxifen
Concept Temperature
Concept Translocation, Genetic
Concept Tryptophan
Concept Ultraviolet Rays
Concept Vidarabine
Concept Xenopus laevis
Concept Blotting, Northern
Concept Blotting, Western
Concept Colorectal Neoplasms
Concept Deoxyribonucleases, Type II Site-Specific
Concept Signal Transduction
Concept Down-Regulation
Concept Tumor Suppressor Protein p53
Concept Resting Phase, Cell Cycle
Concept G1 Phase
Concept G2 Phase
Concept S Phase
Concept Oligonucleotides, Antisense
Concept Mice, SCID
Concept Electrophoresis, Gel, Pulsed-Field
Concept Telomere
Concept Apolipoprotein A-I
Concept Mice, Inbred NOD
Concept Cell Death
Concept Rats, Sprague-Dawley
Concept Apoptosis
Concept Protein Structure, Tertiary
Concept Gap Junctions
Concept Mice, Knockout
Concept Spodoptera
Concept CD8-Positive T-Lymphocytes
Concept Linear Energy Transfer
Concept Proliferating Cell Nuclear Antigen
Concept Cyclin-Dependent Kinases
Concept Telomerase
Concept DNA Methylation
Concept Proto-Oncogene Proteins c-bcl-2
Concept Staurosporine
Concept Chromosome Breakage
Concept Cyclin E
Concept Chromosome Segregation
Concept Caspases
Concept Angiogenesis Inhibitors
Concept Comet Assay
Concept cdc25 Phosphatases
Concept Electrophoretic Mobility Shift Assay
Concept Fluorescence Resonance Energy Transfer
Concept Embryo Research
Concept Information Dissemination
Concept Chromosomes, Mammalian
Concept Adaptor Proteins, Vesicular Transport
Concept RNA, Small Interfering
Concept MicroRNAs
Concept CD11c Antigen
Concept Vascular Endothelial Growth Factor A
Concept CDC2-CDC28 Kinases
Concept Chromosomal Instability
Concept Deoxyribonuclease (Pyrimidine Dimer)
Concept S-Phase Kinase-Associated Proteins
Concept Flavonols
Concept HCT116 Cells
Concept Cell Line, Tumor
Concept Cell Growth Processes
Concept Cell Proliferation
Concept E2F1 Transcription Factor
Concept STAT1 Transcription Factor
Concept STAT2 Transcription Factor
Concept Interferon-Stimulated Gene Factor 3
Concept Interferon-Stimulated Gene Factor 3, gamma Subunit
Concept Proto-Oncogene Proteins c-akt
Concept Cyclin-Dependent Kinase 2
Concept Mice
Concept Rats
Concept DNA-Activated Protein Kinase
Concept Tandem Mass Spectrometry
Concept Protein Stability
Concept Young Adult
Concept HEK293 Cells
Concept Cell Cycle Checkpoints
Concept G2 Phase Cell Cycle Checkpoints
Concept M Phase Cell Cycle Checkpoints
Concept G1 Phase Cell Cycle Checkpoints
Concept Proteolysis
Concept DNA End-Joining Repair
Concept Recombinational DNA Repair
Academic Article Effects of hyperthermia on p53 protein expression and activity.
Academic Article Targeting angiogenic processes by combination low-dose paclitaxel and radiation therapy.
Concept Poly (ADP-Ribose) Polymerase-1
Concept A549 Cells
Concept Triple Negative Breast Neoplasms
Concept Poly(ADP-ribose) Polymerase Inhibitors
Concept Chromothripsis
Concept Anaphase-Promoting Complex-Cyclosome
Concept Checkpoint Kinase 1
Concept Ku Autoantigen
Concept Poly-ADP-Ribose Binding Proteins
Concept Ataxia Telangiectasia Mutated Proteins
Concept ATP Binding Cassette Transporter 1
Concept X-ray Repair Cross Complementing Protein 1
Concept Valosin Containing Protein
Concept MRE11 Homologue Protein
Academic Article Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing.
Academic Article hTERT associates with human telomeres and enhances genomic stability and DNA repair.
Academic Article DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG2 cell line.
Academic Article CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity.
Academic Article Biochemical evidence for Ku-independent backup pathways of NHEJ.
Academic Article Computational Methods for analysis of foci: validation for radiation-induced gamma-H2AX foci in human cells.
Academic Article Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
Academic Article Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.
Academic Article Interferon alpha 2a down-regulates VEGF expression through PI3 kinase and MAP kinase signaling pathways.
Academic Article Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation.
Academic Article Checkpoint abrogation in G2 compromises repair of chromosomal breaks in ataxia telangiectasia cells.
Academic Article ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining.
Academic Article Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks.
Academic Article Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks.
Academic Article DNA damage checkpoint control in cells exposed to ionizing radiation.
Academic Article DNA double strand break repair inhibition as a cause of heat radiosensitization: re-evaluation considering backup pathways of NHEJ.
Academic Article Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Academic Article DNA ligase III as a candidate component of backup pathways of nonhomologous end joining.
Academic Article Reduction in p48-ISGFgamma levels confers resistance to interferon-alpha2a in MHCC97 cells.
Academic Article Evidence for the involvement of Puralpha in response to DNA replication stress.
Academic Article Backup pathways of NHEJ are suppressed by DNA-PK.
Academic Article Initial characterization of a low-molecular-weight factor enhancing the checkpoint response.
Academic Article Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons.
Academic Article DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice.
Academic Article Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways.
Academic Article The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killing.
Academic Article Postreplicative joining of DNA double-strand breaks causes genomic instability in DNA-PKcs-deficient mouse embryonic fibroblasts.
Academic Article The impact of serotonin on the development of bystander damage assessed by ?-H2AX foci analysis.
Academic Article The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
Academic Article SCFSKP2 regulates APC/CCDH1-mediated degradation of CTIP to adjust DNA-end resection in G2-phase.
Academic Article Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
Academic Article PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
Academic Article DEFINED BIOLOGICAL MODELS OF HIGH-LET RADIATION LESIONS.
Academic Article BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
Academic Article Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response.
Academic Article The high toxicity of DSB-clusters modelling high-LET-DNA damage derives from inhibition of c-NHEJ and promotion of alt-EJ and SSA despite increases in HR.
Academic Article Effects of chromatin decondensation on alternative NHEJ.
Academic Article Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment.
Academic Article Abdominopelvic 1.5-T and 3.0-T MR Imaging in Healthy Volunteers: Relationship to Formation of DNA Double-Strand Breaks.
Academic Article An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.
Academic Article Low levels of DNA ligases III and IV sufficient for effective NHEJ.
Academic Article Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.
Academic Article Marked dependence on growth state of backup pathways of NHEJ.
Academic Article Histone H1 functions as a stimulatory factor in backup pathways of NHEJ.
Academic Article Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
Academic Article Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons.
Academic Article DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.
Academic Article Strong Shift to ATR-Dependent Regulation of the G2-Checkpoint after Exposure to High-LET Radiation.
Academic Article DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.
Academic Article Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles.
Academic Article DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.
Academic Article Premature chromosome condensation reveals DNA-PK independent pathways of chromosome break repair.
Academic Article Loss of TGF? signaling increases alternative end-joining DNA repair that sensitizes to genotoxic therapies across cancer types.
Academic Article Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin.
Academic Article PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.
Academic Article ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
Academic Article Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cells.
Academic Article Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.
Academic Article Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.
Academic Article Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
Academic Article Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining.
Academic Article VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair.
Academic Article Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
Academic Article Dependence of adaptive response and its bystander transmission on the genetic background of tested cells.
Academic Article A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks.
Academic Article Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside-Nucleoside Analogue Radiosensitization.
Academic Article Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.
Academic Article Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence.
Academic Article Extensive repair of DNA double-strand breaks in cells deficient in the DNA-PK-dependent pathway of NHEJ after exclusion of heat-labile sites.
Academic Article Application of alkaline sucrose gradient centrifugation in the analysis of DNA replication after DNA damage.
Academic Article The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation.
Academic Article Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.
Academic Article Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.
Academic Article New partners for Chk1.
Academic Article Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.
Academic Article Wolfgang Pohlit (1928-2005).
Academic Article "Praising What Is Lost. . .
Academic Article Lipofection and nucleofection of substrate plasmid can generate widely different readings of DNA end-joining efficiency in different cell lines.
Academic Article Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.
Academic Article Alternative end-joining repair pathways are the ultimate backup for abrogated classical non-homologous end-joining and homologous recombination repair: Implications for the formation of chromosome translocations.
Academic Article A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
Academic Article Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion.
Academic Article Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors.
Academic Article Plasmid-based assays for DNA end-joining in vitro.
Academic Article Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation.
Academic Article Necessities in the Processing of DNA Double Strand Breaks and Their Effects on Genomic Instability and Cancer.
Academic Article Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.
Academic Article Analysis of inhibition of DNA replication in irradiated cells using the SV40-based in vitro assay of DNA replication.
Academic Article Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
Academic Article In vitro rejoining of double-strand breaks in genomic DNA.
Academic Article An ATM-independent S-phase checkpoint response involves CHK1 pathway.
Academic Article Cell line specific modulation of connexin43 expression after exposure to ionizing radiation.
Academic Article Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer.
Academic Article Complete Genome Sequence of the Deep-Sea Bacterium Moritella marina MP-1 (ATCC 15381).
Academic Article Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
Academic Article Increased Gene Targeting in Hyper-Recombinogenic LymphoBlastoid Cell Lines Leaves Unchanged DSB Processing by Homologous Recombination.
Academic Article Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
Academic Article Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
Academic Article NTRK1/TrkA Activation Overrides the G2/M-Checkpoint upon Irradiation.
Academic Article Enhanced use of backup pathways of NHEJ in G2 in Chinese hamster mutant cells with defects in the classical pathway of NHEJ.
Academic Article When a duck is not a duck; a new interdisciplinary synthesis for environmental radiation protection.
Academic Article Impact of Manganese and Chromate on Specific DNA Double-Strand Break Repair Pathways.
Academic Article The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
Academic Article Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.
Academic Article New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement.
Academic Article Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response.
Academic Article Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Pol? inhibition.
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