Thomas Jefferson University

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Iliakis, George
One or more keywords matched the following items that are connected to Iliakis, George
Item TypeName
Concept Enzyme Inhibitors
Concept Growth Inhibitors
Concept Phosphodiesterase Inhibitors
Concept Poly(ADP-ribose) Polymerases
Concept Nucleic Acid Synthesis Inhibitors
Concept Angiogenesis Inhibitors
Concept Protein Kinase Inhibitors
Concept Adenosine Deaminase Inhibitors
Concept Topoisomerase I Inhibitors
Concept Poly (ADP-Ribose) Polymerase-1
Concept Poly(ADP-ribose) Polymerase Inhibitors
Academic Article Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing.
Academic Article CHK1-regulated S-phase checkpoint response reduces camptothecin cytotoxicity.
Academic Article Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
Academic Article Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.
Academic Article Interferon alpha 2a down-regulates VEGF expression through PI3 kinase and MAP kinase signaling pathways.
Academic Article Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks.
Academic Article Backup pathways of NHEJ are suppressed by DNA-PK.
Academic Article PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
Academic Article An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.
Academic Article Low levels of DNA ligases III and IV sufficient for effective NHEJ.
Academic Article Histone H1 functions as a stimulatory factor in backup pathways of NHEJ.
Academic Article PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.
Academic Article Widespread dependence of backup NHEJ on growth state: ramifications for the use of DNA-PK inhibitors.
Academic Article Inhibition of PARP1 by small interfering RNA enhances docetaxel activity against human prostate cancer PC3 cells.
Academic Article Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
Academic Article Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.
Academic Article Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors.
Academic Article G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells.
Academic Article Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
Academic Article Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
Academic Article Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Pol? inhibition.
Academic Article Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Academic Article DNA-PK-independent rejoining of DNA double-strand breaks in human cell extracts in vitro.
Academic Article Effects of adenosine deaminase inhibitor 2'-deoxycoformycin on the repair and expression of potentially lethal damage sensitive to beta-araA.
Academic Article Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts.
Academic Article Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.
Academic Article Mechanisms of DNA double strand break repair and chromosome aberration formation.
Academic Article Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage.
Academic Article Effects of beta-arabinofuranosyladenine on the growth and repair of potentially lethal damage in Ehrilch ascites tumor cells.
Academic Article Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.
Academic Article Down-regulation of DNA replication in extracts of camptothecin-treated cells: activation of an S-phase checkpoint?
Academic Article Effects of aphidicolin on cell proliferation, repair of potentially lethal damage and repair of DNA strand breaks in Ehrlich ascites tumour cells exposed to X-rays.
Academic Article Apoptosis as a predictor of paclitaxel-induced radiosensitization in human tumor cell lines.
Academic Article Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity.
Academic Article Evidence for the induction of two types of potentially lethal damage after exposure of plateau phase Chinese hamster V79 cells to gamma-rays.
Search Criteria
  • Poly ADP ribose Polymerase
  • Inhibitors