Thomas Jefferson University

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Iliakis, George
One or more keywords matched the following items that are connected to Iliakis, George
Item TypeName
Concept Dose-Response Relationship, Radiation
Concept Gamma Rays
Concept Radiation Dosage
Concept Radiation Genetics
Concept Radiation Protection
Concept Radiation Tolerance
Concept Radiation-Protective Agents
Concept Radiation-Sensitizing Agents
Concept Radiation, Ionizing
Concept Ultraviolet Rays
Concept X-Rays
Concept Radiation Oncology
Academic Article Effects of hyperthermia on p53 protein expression and activity.
Academic Article Targeting angiogenic processes by combination low-dose paclitaxel and radiation therapy.
Concept X-ray Repair Cross Complementing Protein 1
Academic Article Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing.
Academic Article DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG2 cell line.
Academic Article Computational Methods for analysis of foci: validation for radiation-induced gamma-H2AX foci in human cells.
Academic Article Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.
Academic Article Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation.
Academic Article Checkpoint abrogation in G2 compromises repair of chromosomal breaks in ataxia telangiectasia cells.
Academic Article ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining.
Academic Article Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks.
Academic Article DNA damage checkpoint control in cells exposed to ionizing radiation.
Academic Article DNA double strand break repair inhibition as a cause of heat radiosensitization: re-evaluation considering backup pathways of NHEJ.
Academic Article Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Academic Article Initial characterization of a low-molecular-weight factor enhancing the checkpoint response.
Academic Article Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons.
Academic Article Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.
Academic Article The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killing.
Academic Article The impact of serotonin on the development of bystander damage assessed by ?-H2AX foci analysis.
Academic Article The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
Academic Article Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
Academic Article PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
Academic Article DEFINED BIOLOGICAL MODELS OF HIGH-LET RADIATION LESIONS.
Academic Article BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
Academic Article Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response.
Academic Article Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells.
Academic Article An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.
Academic Article Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.
Academic Article Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Academic Article Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
Academic Article Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons.
Academic Article DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.
Academic Article Strong Shift to ATR-Dependent Regulation of the G2-Checkpoint after Exposure to High-LET Radiation.
Academic Article DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.
Academic Article Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles.
Academic Article DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.
Academic Article ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
Academic Article Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.
Academic Article Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
Academic Article Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining.
Academic Article Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.
Academic Article Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
Academic Article Preface to the IJRB 60th anniversary special issue "back to our future".
Academic Article Dependence of adaptive response and its bystander transmission on the genetic background of tested cells.
Academic Article A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks.
Academic Article Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside-Nucleoside Analogue Radiosensitization.
Academic Article Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.
Academic Article Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence.
Academic Article Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.
Academic Article Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.
Academic Article Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.
Academic Article Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.
Academic Article The anatomy and cell cycle evolution of DNA damage signaling and repair foci.
Academic Article A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
Academic Article Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion.
Academic Article Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors.
Academic Article Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation.
Academic Article Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).
Academic Article Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.
Academic Article DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin Breaks.
Academic Article G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells.
Academic Article Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
Academic Article Cell line specific modulation of connexin43 expression after exposure to ionizing radiation.
Academic Article Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer.
Academic Article Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
Academic Article Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
Academic Article When a duck is not a duck; a new interdisciplinary synthesis for environmental radiation protection.
Academic Article The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
Academic Article New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement.
Academic Article Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response.
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