Thomas Jefferson University

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Iliakis, George
One or more keywords matched the following items that are connected to Iliakis, George
Item TypeName
Concept Dose-Response Relationship, Radiation
Concept Gamma Rays
Concept Radiation Dosage
Concept Radiation Genetics
Concept Radiation Protection
Concept Radiation Tolerance
Concept Radiation-Protective Agents
Concept Radiation-Sensitizing Agents
Concept Radiation, Ionizing
Concept Ultraviolet Rays
Concept X-Rays
Concept Radiation Oncology
Academic Article Effects of hyperthermia on p53 protein expression and activity.
Academic Article Targeting angiogenic processes by combination low-dose paclitaxel and radiation therapy.
Concept X-ray Repair Cross Complementing Protein 1
Academic Article Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing.
Academic Article DNA-PKcs subunits in radiosensitization by hyperthermia on hepatocellular carcinoma hepG2 cell line.
Academic Article Computational Methods for analysis of foci: validation for radiation-induced gamma-H2AX foci in human cells.
Academic Article Ku affects the ATM-dependent S phase checkpoint following ionizing radiation.
Academic Article Ku affects the CHK1-dependent G(2) checkpoint after ionizing radiation.
Academic Article Checkpoint abrogation in G2 compromises repair of chromosomal breaks in ataxia telangiectasia cells.
Academic Article ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining.
Academic Article Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks.
Academic Article DNA damage checkpoint control in cells exposed to ionizing radiation.
Academic Article DNA double strand break repair inhibition as a cause of heat radiosensitization: re-evaluation considering backup pathways of NHEJ.
Academic Article Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Academic Article Initial characterization of a low-molecular-weight factor enhancing the checkpoint response.
Academic Article Reduced contribution of thermally-labile sugar lesions to DNA double-strand break formation after exposure to neutrons.
Academic Article Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.
Academic Article The yield of DNA double strand breaks determined after exclusion of those forming from heat-labile lesions predicts tumor cell radiosensitivity to killing.
Academic Article The impact of serotonin on the development of bystander damage assessed by ?-H2AX foci analysis.
Academic Article The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia.
Academic Article Disruption of Chromatin Dynamics by Hypotonic Stress Suppresses HR and Shifts DSB Processing to Error-Prone SSA.
Academic Article PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.
Academic Article DEFINED BIOLOGICAL MODELS OF HIGH-LET RADIATION LESIONS.
Academic Article BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.
Academic Article Homology-directed repair is required for the development of radioresistance during S phase: interplay between double-strand break repair and checkpoint response.
Academic Article Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells.
Academic Article An overactivated ATR/CHK1 pathway is responsible for the prolonged G2 accumulation in irradiated AT cells.
Academic Article Selective vulnerability of ARID1A deficient colon cancer cells to combined radiation and ATR-inhibitor therapy.
Academic Article Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Academic Article Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
Academic Article Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons.
Academic Article DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.
Academic Article Strong Shift to ATR-Dependent Regulation of the G2-Checkpoint after Exposure to High-LET Radiation.
Academic Article DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.
Academic Article Biological Response of Human Cancer Cells to Ionizing Radiation in Combination with Gold Nanoparticles.
Academic Article DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy.
Academic Article ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.
Academic Article Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.
Academic Article Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.
Academic Article Nucleoside Analogs Radiosensitize G0 Cells by Activating DNA End Resection and Alternative End-Joining.
Academic Article Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.
Academic Article Depletion of HIF-1a by Inducible Cre/loxP Increases the Sensitivity of Cultured Murine Hepatocytes to Ionizing Radiation in Hypoxia.
Academic Article Preface to the IJRB 60th anniversary special issue "back to our future".
Academic Article Dependence of adaptive response and its bystander transmission on the genetic background of tested cells.
Academic Article A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks.
Academic Article Inhibition of Homologous Recombination and Promotion of Mutagenic Repair of DNA Double-Strand Breaks Underpins Arabinoside-Nucleoside Analogue Radiosensitization.
Academic Article Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.
Academic Article Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence.
Academic Article Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses.
Academic Article Fisetin induces DNA double-strand break and interferes with the repair of radiation-induced damage to radiosensitize triple negative breast cancer cells.
Academic Article Breaks invisible to the DNA damage response machinery accumulate in ATM-deficient cells.
Academic Article Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.
Academic Article The anatomy and cell cycle evolution of DNA damage signaling and repair foci.
Academic Article A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
Academic Article Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion.
Academic Article Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors.
Academic Article Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation.
Academic Article Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).
Academic Article Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells.
Academic Article DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin Breaks.
Academic Article G2/M Checkpoint Abrogation With Selective Inhibitors Results in Increased Chromatid Breaks and Radiosensitization of 82-6 hTERT and RPE Human Cells.
Academic Article Inhibition of Parp1 by BMN673 Effectively Sensitizes Cells to Radiotherapy by Upsetting the Balance of Repair Pathways Processing DNA Double-Strand Breaks.
Academic Article Cell line specific modulation of connexin43 expression after exposure to ionizing radiation.
Academic Article Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer.
Academic Article Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52.
Academic Article Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks.
Academic Article When a duck is not a duck; a new interdisciplinary synthesis for environmental radiation protection.
Academic Article The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.
Academic Article New Facets of DNA Double Strand Break Repair: Radiation Dose as Key Determinant of HR versus c-NHEJ Engagement.
Academic Article Chemical Inhibition of RPA by HAMNO Alters Cell Cycle Dynamics by Impeding DNA Replication and G2-to-M Transition but Has Little Effect on the Radiation-Induced DNA Damage Response.
Academic Article Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group.
Academic Article Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Academic Article Mechanism of radiosensitization by halogenated pyrimidines: the contribution of excess DNA and chromosome damage in BrdU radiosensitization may be minimal in plateau-phase cells.
Academic Article In vitro rejoining of double-strand breaks in genomic DNA.
Academic Article Effects of ionizing radiation on cyclin expression in HeLa cells.
Academic Article Cyclin B expression in HeLa cells during the G2 block induced by ionizing radiation.
Academic Article Effects of beta-arabinofuranosyladenine on potentially lethal damage induced in plateau phase mammalian cells exposed to U.V.-light.
Academic Article Induction and repair of DNA double strand breaks in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc.
Academic Article Effects of adenosine deaminase inhibitor 2'-deoxycoformycin on the repair and expression of potentially lethal damage sensitive to beta-araA.
Academic Article Effects of hyperthermia on the repair of radiation-induced DNA single- and double-strand breaks in DNA double-strand break repair-deficient and repair-proficient cell lines.
Academic Article Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays.
Academic Article Increased frequency of formation of interphase ring-chromosomes in radiosensitive irs-1 cells exposed to X-rays.
Academic Article Evidence for an S-phase checkpoint regulating DNA replication after heat shock: a review.
Academic Article Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts.
Academic Article Quantitative aspects of repair of potentially lethal damage in mammalian cells.
Academic Article Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: comparison with fixation of PLD.
Academic Article Rejoining of DNA double-strand breaks in Ku80-deficient mouse fibroblasts.
Academic Article Ionizing radiation induces two forms of interphase chromosome breaks in Chinese hamster ovary cells that rejoin with different kinetics and show different sensitivity to treatment in hypertonic medium or beta-araA.
Academic Article Investigation of bystander effects in hybrid cells by means of cell fusion and premature chromosome condensation induction.
Academic Article Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on repair of DNA breaks, interphase chromatin breaks, and potentially lethal damage in plateau-phase CHO cells.
Academic Article Radiation-induced potentially lethal damage: DNA lesions susceptible to fixation.
Academic Article Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on cell killing and interphase chromosome breakage in radiation-sensitive cells.
Academic Article Effect of ionizing radiation on the expression of chloramphenicol acetyltransferase gene under the control of commonly used constitutive or inducible promoters.
Academic Article Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing.
Academic Article Hyperthermia does not affect rejoining of DNA double-strand breaks in a cell-free assay.
Academic Article Repair of potentially lethal damage in unfed plateau phase cultures of Ehrlich ascites tumour cells. II. Monolayer cultures.
Academic Article Detection of DNA double-strand breaks in synchronous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis.
Academic Article Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants.
Academic Article Application of non-hypoxic cell sensitizers in radiobiology and radiotherapy: rationale and future prospects.
Academic Article Radioresistance induced in rat embryo cells by transfection with the oncogenes H-ras plus v-myc is cell cycle dependent and maximal during S and G2.
Academic Article Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage.
Academic Article Mitosis-promoting factor activity of inducer mitotic cells may affect radiation yield of interphase chromosome breaks in the premature chromosome condensation assay.
Academic Article Inactivation of Ehrlich ascites tumor cells by heavy ions.
Academic Article Mechanism of radiosensitization by halogenated pyrimidines: bromodeoxyuridine and beta-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateau-phase Chinese hamster ovary cells.
Academic Article The influence of PLD repair on the induction frequency of 6-thioguanine resistant mutants in Ehrlich ascites tumour cells after exposure to X-rays and ultraviolet light.
Academic Article Effects of beta-arabinofuranosyladenine on the growth and repair of potentially lethal damage in Ehrilch ascites tumor cells.
Academic Article Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams.
Academic Article Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.
Academic Article Hypertonic treatment does not affect the radiation yield of interphase chromosome breaks in DNA double-strand break repair-deficient xrs-5 cells.
Academic Article The importance of G1/S-border and mitosis in the fixation of potentially lethal damage.
Academic Article Repair of DNA double-strand breaks and radiosensitivity to killing in an isogenic group of p53 mutant cell lines.
Academic Article Evidence that progression of cells into S-phase is not a prerequisite for recovery between split doses of U.V.-light in synchronized and plateau phase cultures of Ehrlich ascites tumour cells.
Academic Article Evidence for differences among the sectors of potentially lethal damage expressed by hypertonic treatment in plateau-phase V79 cells after exposure to neutrons or gamma rays: the importance of distinction between alpha and beta-PLD forms.
Academic Article Aphidicolin promotes repair of potentially lethal damage in irradiated mammalian cells synchronized in S-phase.
Academic Article The shape of DNA elution dose-response curves under non-denaturing conditions: the contribution of the degree of chromatin condensation.
Academic Article Conditions supporting repair of potentially lethal damage cause a significant reduction of ultraviolet light-induced division delay in synchronized and plateau-phase Ehrlich ascites tumor cells.
Academic Article Induction of DNA double-strand breaks by restriction enzymes in X-ray-sensitive mutant Chinese hamster ovary cells measured by pulsed-field gel electrophoresis.
Academic Article Level of DNA double-strand break rejoining in Chinese hamster xrs-5 cells is dose-dependent: implications for the mechanism of radiosensitivity.
Academic Article Effects of aphidicolin on cell proliferation, repair of potentially lethal damage and repair of DNA strand breaks in Ehrlich ascites tumour cells exposed to X-rays.
Academic Article Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant.
Academic Article The radioresistance to killing of A1-5 cells derives from activation of the Chk1 pathway.
Academic Article Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc.
Academic Article The mutagenicity of alpha particles in Ehrlich ascites tumor cells.
Academic Article Production and repair of chromosome damage in an X-ray sensitive CHO mutant visualized and analysed in interphase using the technique of premature chromosome condensation.
Academic Article Apoptosis as a predictor of paclitaxel-induced radiosensitization in human tumor cell lines.
Academic Article Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity.
Academic Article Modifications in repair and expression of potentially lethal damage (alpha-PLD) as measured by delayed plating or treatment with beta-araA in plateau-phase Ehrlich ascites tumor cells after exposure to charged particles of various specific energies.
Academic Article Effect of arabinofuranosyladenine on radiation-induced chromosome damage in plateau-phase CHO cells measured by premature chromosome condensation: implications for repair and fixation of alpha-PLD.
Academic Article Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines.
Academic Article Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics.
Academic Article Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient.
Academic Article Biological dosimetry of absorbed radiation by C-banding of interphase chromosomes in peripheral blood lymphocytes.
Academic Article Effects of caffeine on X-irradiated synchronous, asynchronous and plateau phase mouse ascites cells: the importance of progression through the cell cycle for caffeine enhancement of killing.
Academic Article Differences in inhibition by beta-arabinofuranosyladenine (araA) of radiation induced DNA damage repair in exponentially growing and plateau-phase CHO-cells.
Academic Article Evidence that repair and expression of potentially lethal damage cause the variations in cell survival after X irradiation observed through the cell cycle in Ehrlich ascites tumor cells.
Academic Article Repair of potentially lethal damage in unfed plateau phase cultures of Ehrlich ascites tumour cells. I. Suspension cultures.
Academic Article Overexpression of insulin-like growth factor (IGF)-I receptor enhances inhibition of DNA replication in mouse cells exposed to x-rays.
Academic Article Persistent inhibition of DNA synthesis after radiation exposure in four clones obtained from rat embryo fibroblasts by transfection with the oncogenes H-ras plus v-myc.
Academic Article The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells.
Academic Article Inhibition of DNA replication by tirapazamine.
Academic Article A DNA double-strand break repair-deficient mutant of CHO cells shows reduced radiosensitization after exposure to hyperthermic temperatures in the plateau phase of growth.
Academic Article Possible importance of PLD repair in the modulation of BrdUrd and IdUrd-mediated radiosensitization in plateau-phase C3H10T1/2 mouse embryo cells.
Academic Article Characterization and properties of repair of potentially lethal damage as measured with the help of beta-arabinofuranosyladenine in plateau-phase EAT cells.
Academic Article Effects of 5'-iododeoxyuridine on the repair of radiation induced potentially lethal damage interphase chromatin breaks and DNA double strand breaks in Chinese hamster ovary cells.
Academic Article Radiosensitive xrs-5 and parental CHO cells show identical DNA neutral filter elution dose-response: implications for a relationship between cell radiosensitivity and induction of DNA double-strand breaks.
Academic Article Possible correlations between cell killing, chromosome damage and DNA repair after X-irradiation.
Academic Article Variation through the cell cycle in the dose-response of DNA neutral filter elution in X-irradiated synchronous CHO-cells.
Academic Article Radiation-sensitive irs mutants rejoin DNA double-strand breaks with efficiency similar to that of parental V79 cells but show altered response to radiation-induced G2 delay.
Academic Article A cell-free assay using cytoplasmic cell extracts to study rejoining of radiation-induced DNA double-strand breaks in human cell nuclei.
Academic Article The catalytic subunit DNA-dependent protein kinase (DNA-PKcs) facilitates recovery from radiation-induced inhibition of DNA replication.
Academic Article Arrest of irradiated G1, S, or G2 cells at mitosis using nocodazole promotes repair of potentially lethal damage.
Academic Article Dose-rate effect on radiation-induced DNA double-strand breaks in the human fibroblast HF19 cell line.
Academic Article Independent forms of potentially lethal damage fixed in plateau-phase Chinese hamster cells by postirradiation treatment in hypertonic salt solution or araA.
Academic Article Evidence for factors modulating radiation-induced G2-delay: potential application as radioprotectors.
Academic Article Evidence for similarities between radiation damage expressed by beta-araA and damage involved in the interaction effect observed after exposure of V79 cells to mixed neutrons and gamma radiation.
Academic Article Evidence for the induction of two types of potentially lethal damage after exposure of plateau phase Chinese hamster V79 cells to gamma-rays.
Academic Article The influence of conditions affecting repair and fixation of potentially lethal damage on the induction of 6-thioguanine resistance after exposure of mammalian cells to X-rays.
Academic Article Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc.
Academic Article Evidence for reduced capacity for damage accumulation and repair in plateau-phase C3H 10T1/2 cells following multiple-dose irradiation with gamma rays.
Search Criteria
  • X Rays