Thomas Jefferson University

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Cook, David
One or more keywords matched the following items that are connected to Cook, David
Item TypeName
Concept Animals
Concept Animals, Newborn
Concept Behavior, Animal
Concept Disease Models, Animal
Grant Glutamate dyshomeostasis: The role of glutamate transport dysfunction in Alzheim
Grant Building translationally relevant relationships between neuropathology and abnormal neuroimaging in Veterans and mechanisms of blast-induced neurotrauma in mice
Academic Article Mechanisms for the inhibition of amiloride-sensitive Na+ absorption by extracellular nucleotides in mouse trachea.
Academic Article Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake.
Academic Article Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice.
Academic Article Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation.
Academic Article Presenilin 1 deficiency alters the activity of voltage-gated Ca2+ channels in cultured cortical neurons.
Academic Article Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms.
Academic Article GLT-1 loss accelerates cognitive deficit onset in an Alzheimer's disease animal model.
Academic Article Amyloid-?1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1.
Academic Article Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.
Academic Article Laterality and region-specific tau phosphorylation correlate with PTSD-related behavioral traits in rats exposed to repetitive low-level blast.
Academic Article Peripheral amyloid-beta levels regulate amyloid-beta clearance from the central nervous system.
Academic Article Repetitive Blast Promotes Chronic Aversion to Neutral Cues Encountered in the Peri-Blast Environment.
Academic Article A novel role for {gamma}-secretase: selective regulation of spontaneous neurotransmitter release from hippocampal neurons.
Academic Article The use of hypertonic saline for treating intracranial hypertension after traumatic brain injury.
Academic Article Nitric oxide synthase mediates cerebellar dysfunction in mice exposed to repetitive blast-induced mild traumatic brain injury.
Academic Article Blast exposure causes early and persistent aberrant phospho- and cleaved-tau expression in a murine model of mild blast-induced traumatic brain injury.
Academic Article ApoE4-associated phospholipid dysregulation contributes to development of Tau hyper-phosphorylation after traumatic brain injury.
Academic Article Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation.
Academic Article Repetitive blast mild traumatic brain injury increases ethanol sensitivity in male mice and risky drinking behavior in male combat veterans.
Academic Article Progressive Cognitive and Post-Traumatic Stress Disorder-Related Behavioral Traits in Rats Exposed to Repetitive Low-Level Blast.
Academic Article Intranasal Paclitaxel Alters Alzheimer's Disease Phenotypic Features in 3xTg-AD Mice.
Academic Article Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit.
Academic Article The dynorphin/kappa opioid receptor mediates adverse immunological and behavioral outcomes induced by repetitive blast trauma.
Academic Article Differential expression of the glutamate transporter GLT-1 in pancreas.
Academic Article Presenilin 1 regulates homeostatic synaptic scaling through Akt signaling.
Academic Article Partial Loss of the Glutamate Transporter GLT-1 Alters Brain Akt and Insulin Signaling in a Mouse Model of Alzheimer's Disease.
Academic Article Chronic dysfunction of astrocytic inwardly rectifying K+ channels specific to the neocortical epileptic focus after fluid percussion injury in the rat.
Academic Article Repetitive Low-Level Blast Exposure Improves Behavioral Deficits and Chronically Lowers A?42 in an Alzheimer Disease Transgenic Mouse Model.
Academic Article Blast exposure elicits blood-brain barrier disruption and repair mediated by tight junction integrity and nitric oxide dependent processes.
Academic Article Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction.
Academic Article Paclitaxel Reduces Brain Injury from Repeated Head Trauma in Mice.
Academic Article Novel application of a Radial Water Tread maze can distinguish cognitive deficits in mice with traumatic brain injury.
Academic Article Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.
Academic Article Localisation of novel forms of glutamate transporters and the cystine-glutamate antiporter in the choroid plexus: Implications for CSF glutamate homeostasis.
Academic Article Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures.
Academic Article The Neurovascular Unit as a Locus of Injury in Low-Level Blast-Induced Neurotrauma.
Academic Article Macroscopic changes in aquaporin-4 underlie blast traumatic brain injury-related impairment in glymphatic function.
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