Thomas Jefferson University

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Wiest, David
One or more keywords matched the following items that are connected to Wiest, David
Item TypeName
Concept Cell Differentiation
Academic Article Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection.
Grant The ThymUS 2016 International Conference on Lymphopoiesis
Grant ThymUS 2020 International Conference on Lymphopoiesis
Academic Article Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells.
Academic Article Early growth response transcription factors are required for development of CD4(-)CD8(-) thymocytes to the CD4(+)CD8(+) stage.
Academic Article Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development.
Academic Article Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint.
Academic Article Origins of ?d T cell effector subsets: a riddle wrapped in an enigma.
Academic Article Enforcement of ?d-lineage commitment by the pre-T-cell receptor in precursors with weak ?d-TCR signals.
Academic Article Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.
Academic Article Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.
Academic Article Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.
Academic Article Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint.
Academic Article Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation.
Academic Article The role of MAPKs in B cell receptor-induced down-regulation of Egr-1 in immature B lymphoma cells.
Academic Article Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.
Academic Article HEB is required for the specification of fetal IL-17-producing ?d T cells.
Academic Article Sustained expression of pre-TCR induced beta-catenin in post-beta-selection thymocytes blocks T cell development.
Academic Article Development of ?d T Cells, the Special-Force Soldiers of the Immune System.
Academic Article Development of ?d T Cells: Soldiers on the Front Lines of Immune Battles.
Academic Article NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma.
Academic Article Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors.
Academic Article Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.
Academic Article Early growth response genes regulate B cell development, proliferation, and immune response.
Academic Article Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.
Academic Article Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.
Academic Article Using the Zebrafish Model to Study T Cell Development.
Academic Article A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.
Academic Article Egr2 is required for Bcl-2 induction during positive selection.
Academic Article Rpl22 Loss Selectively Impairs a? T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.
Academic Article Integration of T-cell receptor, Notch and cytokine signals programs mouse ?d T-cell effector differentiation.
Academic Article Noncanonical mode of ERK action controls alternative a? and ?d T cell lineage fates.
Academic Article Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-? selection thymocytes.
Academic Article Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.
Academic Article The E protein-TCF1 axis controls ?d T?cell development and effector fate.
Academic Article Identification of the last cog in a ligand-independent signaling machine?
Academic Article Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.
Academic Article Pre-TCR-induced beta-catenin facilitates traversal through beta-selection.
Academic Article Ontogenic timing, T?cell receptor signal strength, and Notch signaling direct ?d T?cell functional differentiation in?vivo.
Academic Article Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis.
Academic Article Zebrafish: A Tractable Model for Analysis of T Cell Development.
Academic Article E proteins control the development of NK?dT cells through their invariant T cell receptor.
Academic Article TCF1 dosage determines cell fate during T cell development.
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  • Cell Differentiation