Thomas Jefferson University

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Wiest, David
One or more keywords matched the following items that are connected to Wiest, David
Item TypeName
Concept B-Lymphocyte Subsets
Concept T-Lymphocyte Subsets
Academic Article Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection.
Academic Article Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells.
Academic Article Early growth response transcription factors are required for development of CD4(-)CD8(-) thymocytes to the CD4(+)CD8(+) stage.
Academic Article Origins of ?d T cell effector subsets: a riddle wrapped in an enigma.
Academic Article Enforcement of ?d-lineage commitment by the pre-T-cell receptor in precursors with weak ?d-TCR signals.
Academic Article The TCR ligand-inducible expression of CD73 marks ?d lineage commitment and a metastable intermediate in effector specification.
Academic Article Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.
Academic Article Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.
Academic Article Sustained expression of pre-TCR induced beta-catenin in post-beta-selection thymocytes blocks T cell development.
Academic Article Development of ?d T Cells, the Special-Force Soldiers of the Immune System.
Academic Article Development of ?d T Cells: Soldiers on the Front Lines of Immune Battles.
Academic Article Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors.
Academic Article Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.
Academic Article Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.
Academic Article Rpl22 Loss Selectively Impairs a? T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.
Academic Article Identification of the last cog in a ligand-independent signaling machine?
Academic Article TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes.
Academic Article Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.
Academic Article Role of a selecting ligand in shaping the murine ?d-TCR repertoire.
Academic Article Pre-TCR-induced beta-catenin facilitates traversal through beta-selection.
Academic Article Recent insights into the signals that control alphabeta/gammadelta-lineage fate.
Academic Article E proteins control the development of NK?dT cells through their invariant T cell receptor.
Academic Article Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.
Academic Article TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck.
Academic Article Competitive displacement of pT alpha by TCR-alpha during TCR assembly prevents surface coexpression of pre-TCR and alpha beta TCR.
Academic Article ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
Academic Article Developmental regulation of alpha beta T cell antigen receptor assembly in immature CD4+CD8+ thymocytes.
Academic Article Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
Academic Article Subcellular localization of T-cell receptor complexes containing tyrosine-phosphorylated zeta proteins in immature CD4+CD8+ thymocytes.
Academic Article Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.
Academic Article Altered functional responsiveness of thymocyte subsets from CD3delta-deficient mice to TCR-CD3 engagement.
Academic Article A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly.
Academic Article Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo.
Academic Article Branching out to gain control: how the pre-TCR is linked to multiple functions.
Academic Article Regulation of lineage commitment distinct from positive selection.
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  • T Lymphocyte Subsets