Thomas Jefferson University

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Wiest, David
One or more keywords matched the following items that are connected to Wiest, David
Item TypeName
Concept B-Lymphocytes
Concept Cells, Cultured
Concept Dendritic Cells
Concept Hematopoietic Stem Cells
Concept Killer Cells, Natural
Concept Lymphocytes
Concept Receptors, Antigen, T-Cell
Concept Stem Cells
Concept T-Lymphocytes
Concept T-Lymphocytes, Cytotoxic
Concept Tumor Cells, Cultured
Concept Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Concept CD4-Positive T-Lymphocytes
Concept T-Lymphocyte Subsets
Concept Lymphoma, T-Cell
Concept Receptors, Antigen, T-Cell, gamma-delta
Concept Receptors, Antigen, T-Cell, alpha-beta
Concept Receptor-CD3 Complex, Antigen, T-Cell
Concept CD8-Positive T-Lymphocytes
Concept Jurkat Cells
Concept Genes, T-Cell Receptor beta
Concept Myeloid Cells
Concept T-Cell Antigen Receptor Specificity
Concept Lymphoid Progenitor Cells
Concept Precursor Cells, T-Lymphoid
Concept Natural Killer T-Cells
Concept HEK293 Cells
Academic Article Enforced expression of Spi-B reverses T lineage commitment and blocks beta-selection.
Concept Mouse Embryonic Stem Cells
Concept Intraepithelial Lymphocytes
Grant Regulation of Hematopoiesis by Ribosomal Protein Paralogs
Grant Control of alpha-beta/gamma-delta T Lineage Commitment
Grant Role of RPL22 in Thymocyte Development
Grant Regulation of Hematopoiesis By Ribosomal Protein Paralogs
Grant Role of Egr Proteins in Thymocyte Development
Grant DEVELOPMENTAL CONTROL OF TCR EXPRESSION IN THYMOCYTES
Grant Role of Rpl22 in ER Stress and Colitis
Grant Role of RPL22 in Thymocyte Development
Academic Article Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells.
Academic Article Subversion of T lineage commitment by PU.1 in a clonal cell line system.
Academic Article Early growth response transcription factors are required for development of CD4(-)CD8(-) thymocytes to the CD4(+)CD8(+) stage.
Academic Article Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development.
Academic Article In vitro functional correction of the mutation responsible for murine severe combined immune deficiency by small fragment homologous replacement.
Academic Article Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint.
Academic Article Architectural changes in the TCR:CD3 complex induced by MHC:peptide ligation.
Academic Article Recurrent chromosomal rearrangements implicate oncogenes contributing to T-cell lymphomagenesis in Lck-MyrAkt2 transgenic mice.
Academic Article The Ras/MAPK pathway is required for generation of iNKT cells.
Academic Article Origins of ?d T cell effector subsets: a riddle wrapped in an enigma.
Academic Article Enforcement of ?d-lineage commitment by the pre-T-cell receptor in precursors with weak ?d-TCR signals.
Academic Article The TCR ligand-inducible expression of CD73 marks ?d lineage commitment and a metastable intermediate in effector specification.
Academic Article Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish.
Academic Article A novel recurrent chromosomal inversion implicates the homeobox gene Dlx5 in T-cell lymphomas from Lck-Akt2 transgenic mice.
Academic Article Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.
Academic Article Redundant role for early growth response transcriptional regulators in thymocyte differentiation and survival.
Academic Article Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.
Academic Article Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint.
Academic Article Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation.
Academic Article High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry.
Academic Article The role of MAPKs in B cell receptor-induced down-regulation of Egr-1 in immature B lymphoma cells.
Academic Article Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells.
Academic Article HEB is required for the specification of fetal IL-17-producing ?d T cells.
Academic Article Sustained expression of pre-TCR induced beta-catenin in post-beta-selection thymocytes blocks T cell development.
Academic Article The homeoprotein Dlx5 drives murine T-cell lymphomagenesis by directly transactivating Notch and upregulating Akt signaling.
Academic Article A Novel Germline Heterozygous BCL11B Variant Causing Severe Atopic Disease and Immune Dysregulation.
Academic Article Development of ?d T Cells, the Special-Force Soldiers of the Immune System.
Academic Article Development of ?d T Cells: Soldiers on the Front Lines of Immune Battles.
Academic Article Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.
Academic Article Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.
Academic Article Origins of gammadeltaT cells: a forum for opposing perspectives.
Academic Article Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.
Academic Article Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors.
Academic Article Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.
Academic Article Early growth response genes regulate B cell development, proliferation, and immune response.
Academic Article T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.
Academic Article Cutting edge: Intrinsic programming of thymic ?dT cells for specific peripheral tissue localization.
Academic Article Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.
Academic Article Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.
Academic Article Control of hematopoietic stem cell emergence by antagonistic functions of ribosomal protein paralogs.
Academic Article Using the Zebrafish Model to Study T Cell Development.
Academic Article A role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytes.
Academic Article Egr2 is required for Bcl-2 induction during positive selection.
Academic Article Rpl22 Loss Selectively Impairs a? T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.
Academic Article Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency.
Academic Article Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma.
Academic Article Id3 Restricts ?d NKT Cell Expansion by Controlling Egr2 and c-Myc Activity.
Academic Article Integration of T-cell receptor, Notch and cytokine signals programs mouse ?d T-cell effector differentiation.
Academic Article Noncanonical mode of ERK action controls alternative a? and ?d T cell lineage fates.
Academic Article Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.
Academic Article IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.
Academic Article The E protein-TCF1 axis controls ?d T?cell development and effector fate.
Academic Article Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B.
Academic Article Identification of the last cog in a ligand-independent signaling machine?
Academic Article TCR-mediated ThPOK induction promotes development of mature (CD24-) gammadelta thymocytes.
Academic Article Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.
Academic Article Fli-1 regulates the DN2 to DN3 thymocyte transition and promotes ?d T-cell commitment by enhancing TCR signal strength.
Academic Article Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B.
Academic Article Role of a selecting ligand in shaping the murine ?d-TCR repertoire.
Academic Article Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint.
Academic Article Recent advances in understanding the development and function of ?d T cells.
Academic Article Pre-TCR-induced beta-catenin facilitates traversal through beta-selection.
Academic Article Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B.
Academic Article Reply to Chien: Clarification of the effect of ligand on ?d-TCR repertoire selection.
Academic Article Ontogenic timing, T?cell receptor signal strength, and Notch signaling direct ?d T?cell functional differentiation in?vivo.
Academic Article Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis.
Academic Article Zebrafish: A Tractable Model for Analysis of T Cell Development.
Academic Article Recent insights into the signals that control alphabeta/gammadelta-lineage fate.
Academic Article Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system.
Academic Article Doubling down to make killer T cells.
Academic Article Tissue-infiltrating Alloreactive T Cells Require Id3 to Deflect PD-1-mediated Immune Suppression during GVHD.
Academic Article E proteins control the development of NK?dT cells through their invariant T cell receptor.
Academic Article TCF1 dosage determines cell fate during T cell development.
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  • T Lymphocytes