Item Type | Name |
Concept
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Animals
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Concept
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Behavior, Animal
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Concept
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Disease Models, Animal
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Concept
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Models, Animal
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Concept
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Animals, Genetically Modified
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Academic Article
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Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by antisense oligonucleotides.
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Academic Article
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Targeting Kupffer cells with antisense oligonucleotides.
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Academic Article
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Use of an "acetaldehyde clamp" in the determination of low-KM aldehyde dehydrogenase activity in H4-II-E-C3 rat hepatoma cells.
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Academic Article
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Increases in tumor necrosis factor-alpha in response to thyroid hormone-induced liver oxidative stress in the rat.
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Academic Article
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Complex I regulates mutant mitochondrial aldehyde dehydrogenase activity and voluntary ethanol consumption in rats.
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Academic Article
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Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an ALDH2 antisense mRNA.
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Academic Article
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Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells.
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Academic Article
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Polymorphisms in mitochondrial genes encoding complex I subunits are maternal factors of voluntary alcohol consumption in the rat.
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Academic Article
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Beyond the "First Hit": Marked Inhibition by N-Acetyl Cysteine of Chronic Ethanol Intake But Not of Early Ethanol Intake. Parallel Effects on Ethanol-Induced Saccharin Motivation.
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Academic Article
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Fenofibrate--a lipid-lowering drug--reduces voluntary alcohol drinking in rats.
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Academic Article
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Combined effects of aldehyde dehydrogenase variants and maternal mitochondrial genes on alcohol consumption.
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Academic Article
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The "first hit" toward alcohol reinforcement: role of ethanol metabolites.
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Academic Article
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Reward and relapse: complete gene-induced dissociation in an animal model of alcohol dependence.
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Academic Article
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Intracerebral Stem Cell Administration Inhibits Relapse-like Alcohol Drinking in Rats.
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Academic Article
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Polymorphisms in the mitochondrial aldehyde dehydrogenase gene (Aldh2) determine peak blood acetaldehyde levels and voluntary ethanol consumption in rats.
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Academic Article
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Activation of mitochondrial aldehyde dehydrogenase (ALDH2) by ALDA-1 reduces both the acquisition and maintenance of ethanol intake in rats: A dual mechanism?
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Academic Article
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Innate gut microbiota predisposes to high alcohol consumption.
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Academic Article
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PPARa Agonists Reduce Alcohol Drinking: Do They Act in the Brain or in the Liver?
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Academic Article
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RNA interference against aldehyde dehydrogenase-2: development of tools for alcohol research.
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Academic Article
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Salsolinol, free of isosalsolinol, exerts ethanol-like motivational/sensitization effects leading to increases in ethanol intake.
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Academic Article
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Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption?
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Academic Article
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Intranasal delivery of mesenchymal stem cell-derived exosomes reduces oxidative stress and markedly inhibits ethanol consumption and post-deprivation relapse drinking.
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Academic Article
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Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options.
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Academic Article
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(R)-Salsolinol, a product of ethanol metabolism, stereospecifically induces behavioral sensitization and leads to excessive alcohol intake.
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Academic Article
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Intranasal Administration of Mesenchymal Stem Cell Secretome Reduces Hippocampal Oxidative Stress, Neuroinflammation and Cell Death, Improving the Behavioral Outcome Following Perinatal Asphyxia.
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Academic Article
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A dual treatment blocks alcohol binge-drinking relapse: Microbiota as a new player.
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Academic Article
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Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects.
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Academic Article
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Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking.
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Academic Article
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Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats.
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Academic Article
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Sex differences, alcohol dehydrogenase, acetaldehyde burst, and aversion to ethanol in the rat: a systems perspective.
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Academic Article
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A Novel Morphine Drinking Model of Opioid Dependence in Rats.
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Academic Article
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Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation.
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Academic Article
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Binding of acetaldehyde to a glutathione metabolite: mass spectrometric characterization of an acetaldehyde-cysteinylglycine conjugate.
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Academic Article
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Tolerance to disulfiram induced by chronic alcohol intake in the rat.
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Academic Article
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Gene therapy reduces ethanol intake in an animal model of alcohol dependence.
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Academic Article
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The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake.
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Academic Article
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Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model.
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Academic Article
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Genetic and environmental influences on ethanol consumption: perspectives from preclinical research.
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Academic Article
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A dual mechanism fully blocks ethanol relapse: Role of vagal innervation.
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Academic Article
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Activated mesenchymal stem cell administration inhibits chronic alcohol drinking and suppresses relapse-like drinking in high-alcohol drinker rats.
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Academic Article
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Commonality of Ethanol and Nicotine Reinforcement and Relapse in Wistar-Derived UChB Rats: Inhibition by N-Acetylcysteine.
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Academic Article
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Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats.
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Academic Article
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Effects of acute gamma-hexachlorocyclohexane intoxication in relation to the redox regulation of nuclear factor-kappaB, cytokine gene expression, and liver injury in the rat.
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Academic Article
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The alcohol deprivation effect: marked inhibition by anticatalase gene administration into the ventral tegmental area in rats.
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Academic Article
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Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence.
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Academic Article
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The sequenced rat brain transcriptome--its use in identifying networks predisposing alcohol consumption.
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Academic Article
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Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.
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Academic Article
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Insulin is secreted upon glucose stimulation by both gastrointestinal enteroendocrine K-cells and L-cells engineered with the preproinsulin gene.
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Academic Article
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Chronic Voluntary Morphine Intake Is Associated with Changes in Brain Structures Involved in Drug Dependence in a Rat Model of Polydrug Use.
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