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One or more keywords matched the following items that are connected to Iozzo, Renato
Item TypeName
Concept Animals
Concept Disease Models, Animal
Concept Physical Conditioning, Animal
Concept Animals, Genetically Modified
Academic Article Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans.
Academic Article Letter from Renato V. Iozzo. Matrix Biology.
Academic Article Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice.
Academic Article Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.
Academic Article Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.
Academic Article Proteoglycans in cancer biology, tumour microenvironment and angiogenesis.
Academic Article A role for decorin in a murine model of allergen-induced asthma.
Academic Article A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin.
Academic Article Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells.
Academic Article Endorepellin, the angiostatic module of perlecan, interacts with both the a2ß1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.
Academic Article Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis.
Academic Article Pathophysiological mechanisms of autosomal dominant congenital stromal corneal dystrophy: C-terminal-truncated decorin results in abnormal matrix assembly and altered expression of small leucine-rich proteoglycans.
Academic Article Autophagic tumor stroma: a biofuel for cancer growth.
Academic Article The role for decorin in delayed-type hypersensitivity.
Academic Article Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.
Academic Article The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells.
Academic Article Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice.
Academic Article Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1a, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
Academic Article Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition.
Academic Article Decorin-TGFß axis in hepatic fibrosis and cirrhosis.
Academic Article Thrombospondins in physiology and disease: new tricks for old dogs.
Academic Article Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A.
Academic Article Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon.
Academic Article Decorin: a guardian from the matrix.
Academic Article Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction.
Academic Article Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin.
Academic Article Alcoholic pancreatitis in rats: injury from nonoxidative metabolites of ethanol.
Academic Article Decorin suppresses tumor cell-mediated angiogenesis.
Academic Article Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope.
Academic Article In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.
Academic Article Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons.
Academic Article The role of decorin in collagen fibrillogenesis and skin homeostasis.
Academic Article Strain-rate sensitive mechanical properties of tendon fascicles from mice with genetically engineered alterations in collagen and decorin.
Academic Article Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury.
Academic Article Investigating tendon fascicle structure-function relationships in a transgenic-age mouse model using multiple regression models.
Academic Article Protective niche for Borrelia burgdorferi to evade humoral immunity.
Academic Article Alterations in lung mechanics in decorin-deficient mice.
Academic Article Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.
Academic Article BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan.
Academic Article Matrix revolutions: "tails" of basement-membrane components with angiostatic functions.
Academic Article Decorin prevents metastatic spreading of breast cancer.
Academic Article Decorin, a novel player in the insulin-like growth factor system.
Academic Article Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice.
Academic Article A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.
Academic Article A role for decorin in the remodeling of myocardial infarction.
Academic Article Extracellular matrix proteoglycans control the fate of bone marrow stromal cells.
Academic Article Basement membrane proteoglycans: from cellar to ceiling.
Academic Article Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation.
Academic Article Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development.
Academic Article Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation.
Academic Article Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation.
Academic Article A role for decorin in cutaneous wound healing and angiogenesis.
Academic Article Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism.
Academic Article Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice.
Academic Article Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.
Academic Article The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis.
Academic Article Effect of PEEP on induced constriction is enhanced in decorin-deficient mice.
Academic Article Decorin deficiency enhances progressive nephropathy in diabetic mice.
Academic Article Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices.
Academic Article Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity.
Academic Article Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
Academic Article Novel interactions of perlecan: unraveling perlecan's role in angiogenesis.
Academic Article Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices.
Academic Article A central function for perlecan in skeletal muscle and cardiovascular development.
Academic Article Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.
Academic Article Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.
Academic Article Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway.
Academic Article Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis.
Academic Article An antimetastatic role for decorin in breast cancer.
Academic Article Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs.
Academic Article Diverse cell signaling events modulated by perlecan.
Academic Article Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan.
Academic Article A central role for decorin during vertebrate convergent extension.
Academic Article Genetic evidence for key roles of decorin and biglycan in dentin mineralization.
Academic Article Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis.
Academic Article Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis.
Academic Article A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis.
Academic Article Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.
Academic Article Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.
Academic Article Collagen fibril organization in the pregnant endometrium of decorin-deficient mice.
Academic Article Effect of age and proteoglycan deficiency on collagen fiber re-alignment and mechanical properties in mouse supraspinatus tendon.
Academic Article Steroid Hormones Are Key Modulators of Tissue Mechanical Function via Regulation of Collagen and Elastic Fibers.
Academic Article Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin.
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