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Iozzo, Renato

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Item Type	Name
Concept	Down-Regulation
Academic Article	Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.
Academic Article	Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells.
Academic Article	Endorepellin, the angiostatic module of perlecan, interacts with both the a2ß1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.
Academic Article	Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1a, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
Academic Article	Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A.
Academic Article	Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.
Academic Article	Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis.
Academic Article	Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.
Academic Article	Proepithelin is an autocrine growth factor for bladder cancer.
Grant	The Biology of Perlecan in Cancer and Angiogenesis

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Down Regulation

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