Thomas Jefferson University

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Iozzo, Renato
One or more keywords matched the following items that are connected to Iozzo, Renato
Item TypeName
Concept Bacterial Outer Membrane Proteins
Concept Bacterial Proteins
Concept Carrier Proteins
Concept DNA-Binding Proteins
Concept Luminescent Proteins
Concept Microfilament Proteins
Concept Nerve Tissue Proteins
Concept Pregnancy Proteins
Concept Protein Binding
Concept Protein Denaturation
Concept Protein Kinases
Concept Protein Precursors
Concept Protein Processing, Post-Translational
Concept Protein-Tyrosine Kinases
Concept Proteins
Concept Proto-Oncogene Proteins
Concept Recombinant Fusion Proteins
Concept Recombinant Proteins
Concept Protein Biosynthesis
Concept Protein Engineering
Concept Proto-Oncogene Proteins c-myc
Concept Extracellular Matrix Proteins
Concept RNA-Binding Proteins
Concept Protein-Serine-Threonine Kinases
Concept Protein Structure, Tertiary
Concept Cyclic AMP-Dependent Protein Kinases
Concept Cell Cycle Proteins
Concept Bone Morphogenetic Proteins
Concept Proto-Oncogene Proteins c-met
Concept Mitogen-Activated Protein Kinase 1
Concept rhoA GTP-Binding Protein
Concept Receptor Protein-Tyrosine Kinases
Concept Mitogen-Activated Protein Kinases
Concept Protein Transport
Concept Tumor Suppressor Proteins
Concept Protein Interaction Mapping
Concept Adaptor Proteins, Vesicular Transport
Concept Intercellular Signaling Peptides and Proteins
Concept Angiostatic Proteins
Concept Intracellular Signaling Peptides and Proteins
Concept p38 Mitogen-Activated Protein Kinases
Concept Mitogen-Activated Protein Kinase 3
Concept Green Fluorescent Proteins
Concept Proto-Oncogene Proteins c-cbl
Concept Apoptosis Regulatory Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Oncogene Protein v-akt
Concept Focal Adhesion Protein-Tyrosine Kinases
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 6
Concept Bone Morphogenetic Protein 1
Concept Insulin Receptor Substrate Proteins
Concept Protein Stability
Academic Article The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin.
Academic Article Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan.
Academic Article Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans.
Academic Article Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.
Academic Article Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.
Academic Article A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin.
Academic Article Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells.
Academic Article Endorepellin, the angiostatic module of perlecan, interacts with both the a2ß1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.
Academic Article Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling.
Academic Article Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.
Academic Article Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice.
Academic Article Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1a, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
Academic Article Thrombospondins in physiology and disease: new tricks for old dogs.
Academic Article Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A.
Academic Article Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.
Academic Article Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.
Academic Article Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction.
Academic Article Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin.
Academic Article Decorin suppresses tumor cell-mediated angiogenesis.
Academic Article Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope.
Academic Article Androgen receptor expression induces FGF2, FGF-binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth, survival, and androgen receptor down-modulation.
Academic Article Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan.
Academic Article Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis.
Academic Article In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.
Academic Article Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons.
Academic Article Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly.
Academic Article A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth.
Academic Article The role of decorin in collagen fibrillogenesis and skin homeostasis.
Academic Article Biologically active decorin is a monomer in solution.
Academic Article Strain-rate sensitive mechanical properties of tendon fascicles from mice with genetically engineered alterations in collagen and decorin.
Academic Article Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.
Academic Article Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury.
Academic Article Investigating tendon fascicle structure-function relationships in a transgenic-age mouse model using multiple regression models.
Academic Article Protective niche for Borrelia burgdorferi to evade humoral immunity.
Academic Article Alterations in lung mechanics in decorin-deficient mice.
Academic Article Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.
Academic Article BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan.
Academic Article Matrix revolutions: "tails" of basement-membrane components with angiostatic functions.
Academic Article Decorin prevents metastatic spreading of breast cancer.
Academic Article Decorin, a novel player in the insulin-like growth factor system.
Academic Article Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice.
Academic Article A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.
Academic Article A role for decorin in the remodeling of myocardial infarction.
Academic Article Extracellular matrix proteoglycans control the fate of bone marrow stromal cells.
Academic Article The role of proteomics in the assessment of premature rupture of fetal membranes.
Academic Article Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis.
Academic Article Basement membrane proteoglycans: from cellar to ceiling.
Academic Article Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation.
Academic Article Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development.
Academic Article Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation.
Academic Article Proepithelin promotes migration and invasion of 5637 bladder cancer cells through the activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex.
Academic Article Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation.
Academic Article A role for decorin in cutaneous wound healing and angiogenesis.
Academic Article Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism.
Academic Article Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice.
Academic Article Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor.
Academic Article Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.
Academic Article The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis.
Academic Article Effect of PEEP on induced constriction is enhanced in decorin-deficient mice.
Academic Article Decorin deficiency enhances progressive nephropathy in diabetic mice.
Academic Article Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices.
Academic Article Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity.
Academic Article Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
Academic Article Novel interactions of perlecan: unraveling perlecan's role in angiogenesis.
Academic Article Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices.
Academic Article Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.
Academic Article Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.
Academic Article An antimetastatic role for decorin in breast cancer.
Academic Article Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs.
Academic Article Diverse cell signaling events modulated by perlecan.
Academic Article Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan.
Academic Article Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth.
Academic Article A central role for decorin during vertebrate convergent extension.
Academic Article Proepithelin is an autocrine growth factor for bladder cancer.
Academic Article Genetic evidence for key roles of decorin and biglycan in dentin mineralization.
Academic Article Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis.
Academic Article Decorin is a novel antagonistic ligand of the Met receptor.
Academic Article A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis.
Academic Article Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.
Academic Article Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.
Academic Article Collagen fibril organization in the pregnant endometrium of decorin-deficient mice.
Academic Article c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.
Grant Natural EGFR Antagonists and Cancer
Grant The Biology of Perlecan in Cancer and Angiogenesis
Grant Progranulin signaling in bladder cancer
Academic Article Steroid Hormones Are Key Modulators of Tissue Mechanical Function via Regulation of Collagen and Elastic Fibers.
Academic Article EphA2 is a functional receptor for the growth factor progranulin.
Academic Article Decorin-An Antagonist of TGF-ß in Astrocytes of the Optic Nerve.
Academic Article Decorin regulates collagen fibrillogenesis during corneal wound healing in mouse in vivo.
Academic Article Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy.
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  • GTP Binding Proteins