Thomas Jefferson University

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Manser, Timothy
One or more keywords matched the following items that are connected to Manser, Timothy
Item TypeName
Concept Germinal Center
Academic Article Expression of cellular FLIP by B cells is required for their participation in an immune response.
Academic Article Cutting edge: macrophages are required for localization of antigen-activated B cells to the follicular perimeter and the subsequent germinal center response.
Academic Article Differential expression of the inhibitory IgG Fc receptor FcgammaRIIB on germinal center cells: implications for selection of high-affinity B cells.
Academic Article Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice.
Academic Article Dominant, hierarchical induction of peripheral tolerance during foreign antigen-driven B cell development.
Academic Article Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice.
Academic Article Textbook germinal centers?
Academic Article B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers.
Academic Article Failed up-regulation of the inhibitory IgG Fc receptor Fc gamma RIIB on germinal center B cells in autoimmune-prone mice is not associated with deletion polymorphisms in the promoter region of the Fc gamma RIIB gene.
Academic Article An antibody VH gene that promotes marginal zone B cell development and heavy chain allelic inclusion.
Academic Article FcgammaRIIB regulates autoreactive primary antibody-forming cell, but not germinal center B cell, activity.
Academic Article Quantitatively reduced participation of anti-nuclear antigen B cells that down-regulate B cell receptor during primary development in the germinal center/memory B cell response to foreign antigen.
Academic Article Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles.
Academic Article The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints.
Grant Regulation of Persistent Antibody Responses by FC Receptors
Grant Regulation of Persistent Ab Responses by Fc Receptors
Grant Antigen-driven B cell development at the follicular perimeter
Grant Negative Selective of Autoreactive Antibodies
Grant A New Model for Studying Antigen-driven B cell Tolerance
Grant REGULATION OF PERSISTENT AB RESPONSE BY FC RECEPTORS
Grant Negative selection of autoreactive antibodies
Grant EXPRESSION OF ANTIBODY DIVERSITY DURING IMMUNE RESPONSES
Academic Article Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production.
Academic Article Amplified follicular immune complex deposition in mice lacking the Fc receptor gamma-chain does not alter maturation of the B cell response.
Academic Article Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses.
Academic Article Insights into the mechanisms of antibody-affinity maturation and the generation of the memory B-cell compartment using genetically altered mice.
Academic Article Cutting edge: germinal centers can be induced in the absence of T cells.
Academic Article Self-limiting systemic autoimmune disease during reconstitution of T cell-deficient mice with syngeneic T cells: support for a multifaceted role of T cells in the maintenance of peripheral B cell tolerance.
Academic Article Severe attenuation of the B cell immune response in Msh2-deficient mice.
Academic Article A periarteriolar lymphoid sheath-associated B cell focus response is not observed during the development of the anti-arsonate germinal center reaction.
Academic Article The T cell-dependent B cell immune response and germinal center reaction are intact in A-myb-deficient mice.
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  • Germinal Center