Item Type | Name |
Concept
|
Adenocarcinoma
|
Concept
|
Adenosine Triphosphate
|
Concept
|
Aged
|
Concept
|
Aged, 80 and over
|
Concept
|
Air
|
Concept
|
Amino Acid Sequence
|
Concept
|
Animals
|
Concept
|
Anti-Inflammatory Agents, Non-Steroidal
|
Concept
|
Antibodies
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Antibodies, Viral
|
Concept
|
Antibody Affinity
|
Concept
|
Antibody Specificity
|
Concept
|
Immunotoxins
|
Concept
|
Epitopes
|
Concept
|
Antigens, Differentiation
|
Concept
|
Histocompatibility Antigens Class II
|
Concept
|
Antigens, Neoplasm
|
Concept
|
Antigens, Surface
|
Concept
|
Antimetabolites, Antineoplastic
|
Concept
|
Antineoplastic Agents
|
Concept
|
Astrocytoma
|
Concept
|
Base Sequence
|
Concept
|
Benzenesulfonates
|
Concept
|
Benzylidene Compounds
|
Concept
|
Binding Sites
|
Concept
|
Biological Transport
|
Concept
|
Urinary Bladder Neoplasms
|
Concept
|
Boronic Acids
|
Concept
|
Breast Neoplasms
|
Concept
|
Calcium
|
Concept
|
Carcinogens
|
Concept
|
Carcinoma
|
Concept
|
Carcinoma in Situ
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
Concept
|
Carcinoma, Renal Cell
|
Concept
|
Carcinoma, Squamous Cell
|
Concept
|
Cell Compartmentation
|
Concept
|
Cell Cycle
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Division
|
Concept
|
Cell Movement
|
Concept
|
Cell Nucleus
|
Concept
|
Cell Separation
|
Concept
|
Cell Transformation, Neoplastic
|
Concept
|
Cell Transformation, Viral
|
Concept
|
Uterine Cervical Neoplasms
|
Concept
|
Chickens
|
Concept
|
Chromatin
|
Concept
|
Chromones
|
Concept
|
Chromosome Aberrations
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Colonic Neoplasms
|
Concept
|
Combined Modality Therapy
|
Concept
|
Cross-Linking Reagents
|
Concept
|
Culture Media
|
Concept
|
Cysteine
|
Concept
|
Cytomegalovirus
|
Concept
|
Cytoplasm
|
Concept
|
Dendritic Cells
|
Concept
|
Drug Eruptions
|
Concept
|
Dermatologic Agents
|
Concept
|
Dermatology
|
Concept
|
Diabetes Mellitus
|
Concept
|
Disease Models, Animal
|
Concept
|
DNA
|
Concept
|
DNA Replication
|
Concept
|
DNA, Neoplasm
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Dose-Response Relationship, Radiation
|
Concept
|
Drosophila melanogaster
|
Concept
|
Drug Screening Assays, Antitumor
|
Concept
|
Drug Synergism
|
Concept
|
Dyneins
|
Concept
|
Electrophoresis, Polyacrylamide Gel
|
Concept
|
Endothelium, Vascular
|
Concept
|
Enzyme Activation
|
Concept
|
Enzyme Inhibitors
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Epidermal Growth Factor
|
Concept
|
Epidermolysis Bullosa
|
Concept
|
Epithelial Cells
|
Concept
|
Amifostine
|
Concept
|
Eye
|
Concept
|
Fibronectins
|
Concept
|
Flavonoids
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Fluorescent Dyes
|
Concept
|
Fluorouracil
|
Concept
|
Follow-Up Studies
|
Concept
|
Frozen Sections
|
Concept
|
Gangliosides
|
Concept
|
Gene Amplification
|
Concept
|
Genes, Regulator
|
Concept
|
Glioblastoma
|
Concept
|
Glioma
|
Concept
|
Glycolipids
|
Concept
|
Glycoproteins
|
Concept
|
Growth Substances
|
Concept
|
Cricetinae
|
Concept
|
Head and Neck Neoplasms
|
Concept
|
HeLa Cells
|
Concept
|
Histone Deacetylases
|
Concept
|
HLA-DR Antigens
|
Concept
|
Hormones
|
Concept
|
Humans
|
Concept
|
Hybridomas
|
Concept
|
Hypoglycemic Agents
|
Concept
|
Immunoglobulin G
|
Concept
|
Immune Tolerance
|
Concept
|
Immunoenzyme Techniques
|
Concept
|
Immunoglobulin Fragments
|
Concept
|
Immunoglobulin Isotypes
|
Concept
|
Immunohistochemistry
|
Concept
|
Immunosuppressive Agents
|
Concept
|
Immunotherapy
|
Concept
|
Indoles
|
Concept
|
Infant, Newborn
|
Concept
|
Insulin
|
Concept
|
Insulin-Like Growth Factor I
|
Concept
|
Interferon-gamma
|
Concept
|
Interleukin-1
|
Concept
|
Interleukin-2
|
Concept
|
Interphase
|
Concept
|
Intestinal Mucosa
|
Concept
|
Iodine Radioisotopes
|
Concept
|
Kidney Function Tests
|
Concept
|
Kidney Neoplasms
|
Concept
|
Killer Cells, Natural
|
Concept
|
Kinetics
|
Concept
|
Lewis Blood-Group System
|
Concept
|
Ligands
|
Concept
|
Liver Neoplasms, Experimental
|
Concept
|
Luciferases
|
Concept
|
Lung Neoplasms
|
Concept
|
Lymphatic Metastasis
|
Concept
|
Lymphocyte Activation
|
Concept
|
Lymphocytes
|
Concept
|
Lymphokines
|
Concept
|
Macrophages
|
Concept
|
Melanocytes
|
Concept
|
Melanoma
|
Concept
|
Melanoma, Experimental
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Mesothelioma
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Mice, Nude
|
Concept
|
Mice, Transgenic
|
Concept
|
Microscopy, Fluorescence
|
Concept
|
Middle Aged
|
Concept
|
Models, Genetic
|
Concept
|
Models, Molecular
|
Concept
|
Models, Structural
|
Concept
|
Molecular Conformation
|
Concept
|
Molecular Sequence Data
|
Concept
|
Monocytes
|
Concept
|
Morpholines
|
Concept
|
Mutagens
|
Concept
|
National Institutes of Health (U.S.)
|
Concept
|
Neoplasm Invasiveness
|
Concept
|
Neoplasm Metastasis
|
Concept
|
Neoplasms, Experimental
|
Concept
|
Neovascularization, Pathologic
|
Concept
|
Neutralization Tests
|
Concept
|
Nevus
|
Concept
|
Nevus, Pigmented
|
Concept
|
Oligodendroglioma
|
Concept
|
Oligodeoxyribonucleotides
|
Concept
|
Organ Culture Techniques
|
Concept
|
Osteochondrodysplasias
|
Concept
|
Pancreatic Neoplasms
|
Concept
|
Phosphorylation
|
Concept
|
Plasminogen Activators
|
Concept
|
Platelet-Derived Growth Factor
|
Concept
|
Pleural Neoplasms
|
Concept
|
Precipitin Tests
|
Concept
|
Predictive Value of Tests
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Prostate
|
Concept
|
Protease Inhibitors
|
Concept
|
Protein Binding
|
Concept
|
Protein Conformation
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Proto-Oncogenes
|
Concept
|
Protons
|
Concept
|
Pyrroles
|
Concept
|
Quinazolines
|
Concept
|
Rabbits
|
Concept
|
Radiation Injuries, Experimental
|
Concept
|
Radiation Protection
|
Concept
|
Radiation-Protective Agents
|
Concept
|
Radiation-Sensitizing Agents
|
Concept
|
Radiochemistry
|
Concept
|
Radioimmunoassay
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Receptor, Epidermal Growth Factor
|
Concept
|
Rectal Neoplasms
|
Concept
|
Risk Factors
|
Concept
|
RNA Caps
|
Concept
|
RNA Splicing
|
Concept
|
RNA, Messenger
|
Concept
|
RNA, Neoplasm
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Sequence Homology, Nucleic Acid
|
Concept
|
Skin Neoplasms
|
Concept
|
Structure-Activity Relationship
|
Concept
|
Substrate Specificity
|
Concept
|
T-Lymphocytes
|
Concept
|
T-Lymphocytes, Cytotoxic
|
Concept
|
Tetracycline
|
Concept
|
Tetradecanoylphorbol Acetate
|
Concept
|
Toluene
|
Concept
|
Transcription, Genetic
|
Concept
|
Protein Biosynthesis
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Tumor Stem Cell Assay
|
Concept
|
Ultraviolet Rays
|
Concept
|
United States
|
Concept
|
Urokinase-Type Plasminogen Activator
|
Concept
|
Vulvar Neoplasms
|
Concept
|
Zebrafish
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Northern
|
Concept
|
Blotting, Western
|
Concept
|
Colorectal Neoplasms
|
Concept
|
Drug Design
|
Concept
|
Reproducibility of Results
|
Concept
|
Second Messenger Systems
|
Concept
|
Transforming Growth Factors
|
Concept
|
Histocompatibility Antigens Class I
|
Concept
|
Signal Transduction
|
Concept
|
Leukemia, Myeloid, Acute
|
Concept
|
Down-Regulation
|
Concept
|
Inositol 1,4,5-Trisphosphate
|
Concept
|
Keratinocytes
|
Concept
|
Osteonectin
|
Concept
|
Cell Adhesion Molecules
|
Concept
|
Cadherins
|
Concept
|
Cysteine Proteinase Inhibitors
|
Concept
|
Up-Regulation
|
Concept
|
Killer Cells, Lymphokine-Activated
|
Concept
|
Survival Rate
|
Concept
|
Cluster Analysis
|
Concept
|
Survival Analysis
|
Concept
|
Case-Control Studies
|
Concept
|
Integrins
|
Concept
|
Epidermolysis Bullosa Dystrophica
|
Concept
|
Immunophenotyping
|
Concept
|
Polymerase Chain Reaction
|
Concept
|
Genes, p53
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
Genes, Wilms Tumor
|
Concept
|
S Phase
|
Concept
|
Cytokines
|
Concept
|
Interleukin-8
|
Concept
|
Transforming Growth Factor alpha
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Fibroblast Growth Factor 2
|
Concept
|
Endothelial Growth Factors
|
Concept
|
Microscopy, Immunoelectron
|
Concept
|
Baculoviridae
|
Concept
|
DNA, Antisense
|
Concept
|
Oligonucleotides, Antisense
|
Concept
|
CHO Cells
|
Concept
|
3T3 Cells
|
Concept
|
Radioimmunotherapy
|
Concept
|
Mice, SCID
|
Concept
|
Central Nervous System Neoplasms
|
Concept
|
Interleukin-10
|
Concept
|
Culture Media, Serum-Free
|
Concept
|
Treatment Outcome
|
Concept
|
Interferon-alpha
|
Concept
|
Culture Media, Conditioned
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Apoptosis
|
Concept
|
Point Mutation
|
Concept
|
Sequence Homology
|
Concept
|
Protein Structure, Secondary
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Receptors, Fibroblast Growth Factor
|
Concept
|
Receptors, Nerve Growth Factor
|
Concept
|
Receptor, IGF Type 1
|
Concept
|
Gap Junctions
|
Concept
|
Connexins
|
Concept
|
Age Distribution
|
Concept
|
Cell Transplantation
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
Concept
|
Calcium-Calmodulin-Dependent Protein Kinases
|
Concept
|
Genes, Reporter
|
Concept
|
Receptors, Growth Factor
|
Concept
|
Antibodies, Bispecific
|
Concept
|
DNA, Complementary
|
Concept
|
Receptors, Tumor Necrosis Factor
|
Concept
|
Receptors, Transforming Growth Factor beta
|
Concept
|
Mice, Knockout
|
Concept
|
Crystallography, X-Ray
|
Concept
|
Th1 Cells
|
Concept
|
Th2 Cells
|
Concept
|
Disease Progression
|
Concept
|
Epitope Mapping
|
Concept
|
ras Proteins
|
Concept
|
Interleukin-12
|
Concept
|
Inflammation Mediators
|
Concept
|
Hair Follicle
|
Concept
|
src Homology Domains
|
Concept
|
Coculture Techniques
|
Concept
|
Cell Culture Techniques
|
Concept
|
Proto-Oncogene Proteins c-kit
|
Concept
|
Fluorescent Antibody Technique, Indirect
|
Concept
|
Stem Cell Factor
|
Concept
|
Jurkat Cells
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
Concept
|
Radiopharmaceuticals
|
Concept
|
Vaccines, DNA
|
Concept
|
Phosphatidylinositol 3-Kinases
|
Concept
|
Nuclear Magnetic Resonance, Biomolecular
|
Concept
|
Proto-Oncogene Proteins c-raf
|
Concept
|
Nuclear Localization Signals
|
Concept
|
Cyclin A
|
Concept
|
Cyclin D1
|
Concept
|
Amino Acid Substitution
|
Concept
|
Calcium Signaling
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Tyrphostins
|
Concept
|
Mutation, Missense
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Peptide Nucleic Acids
|
Concept
|
Caspases
|
Concept
|
Caspase 1
|
Concept
|
Oligodeoxyribonucleotides, Antisense
|
Concept
|
Surface Plasmon Resonance
|
Concept
|
Interleukin-18
|
Concept
|
GTP Phosphohydrolases
|
Concept
|
Matrix Metalloproteinase 2
|
Concept
|
Matrix Metalloproteinase 9
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
Concept
|
Amino Acid Motifs
|
Concept
|
rac1 GTP-Binding Protein
|
Concept
|
Protein Structure, Quaternary
|
Concept
|
Mitogen-Activated Protein Kinases
|
Concept
|
Mitogen-Activated Protein Kinase Kinases
|
Concept
|
MAP Kinase Kinase Kinases
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
Carcinoma, Pancreatic Ductal
|
Concept
|
Active Transport, Cell Nucleus
|
Concept
|
Complementarity Determining Regions
|
Concept
|
Xenograft Model Antitumor Assays
|
Concept
|
Anoikis
|
Concept
|
Models, Animal
|
Concept
|
Collagen Type VII
|
Concept
|
Collagen Type XI
|
Concept
|
Chromosome Disorders
|
Concept
|
Drosophila Proteins
|
Concept
|
Zebrafish Proteins
|
Concept
|
Animals, Genetically Modified
|
Concept
|
Myocytes, Cardiac
|
Concept
|
RNA, Small Interfering
|
Concept
|
Biomedical Research
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Fullerenes
|
Concept
|
Integrin alpha2
|
Concept
|
Integrin alpha3
|
Concept
|
Receptors, Vascular Endothelial Growth Factor
|
Concept
|
Vascular Endothelial Growth Factor Receptor-1
|
Concept
|
NIH 3T3 Cells
|
Concept
|
Vascular Endothelial Growth Factors
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Angiogenesis Inducing Agents
|
Concept
|
Cell Line, Tumor
|
Concept
|
Culture Techniques
|
Concept
|
Microscopy, Electron, Transmission
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
MAP Kinase Kinase 1
|
Concept
|
Proto-Oncogene Proteins B-raf
|
Concept
|
Cell Proliferation
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
History, 20th Century
|
Concept
|
History, 21st Century
|
Concept
|
STAT3 Transcription Factor
|
Concept
|
Apoptosis Regulatory Proteins
|
Concept
|
bcl-X Protein
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
PTEN Phosphohydrolase
|
Concept
|
Catenins
|
Concept
|
Desmoglein 2
|
Concept
|
Mice
|
Concept
|
Rats
|
Concept
|
Protein Kinase C-delta
|
Concept
|
Early Growth Response Protein 1
|
Concept
|
Early Growth Response Protein 3
|
Concept
|
Benzothiazoles
|
Concept
|
Caspase 3
|
Concept
|
Fas Ligand Protein
|
Concept
|
Caspase 14
|
Concept
|
Interleukin 1 Receptor Antagonist Protein
|
Concept
|
Nanoparticles
|
Concept
|
Transforming Growth Factor beta1
|
Concept
|
Transforming Growth Factor beta2
|
Concept
|
Transforming Growth Factor beta3
|
Concept
|
Precursor Cell Lymphoblastic Leukemia-Lymphoma
|
Concept
|
p21-Activated Kinases
|
Concept
|
Protein Phosphatase 2
|
Concept
|
Cardiotoxins
|
Concept
|
Molecular Dynamics Simulation
|
Concept
|
Cytoplasmic Dyneins
|
Concept
|
Single-Chain Antibodies
|
Concept
|
Melanoma-Specific Antigens
|
Concept
|
Tetraspanins
|
Concept
|
Morpholinos
|
Concept
|
Antibodies, Monoclonal, Humanized
|
Concept
|
Caspase Inhibitors
|
Concept
|
Proteasome Inhibitors
|
Academic Article
|
Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor.
|
Academic Article
|
Progress in epidermolysis bullosa research: toward treatment and cure.
|
Academic Article
|
Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1.
|
Academic Article
|
An episomal vector for stable tetracycline-regulated gene expression.
|
Academic Article
|
Differential regulation of p53 function by the N-terminal ?Np53 and ?113p53 isoforms in zebrafish embryos.
|
Academic Article
|
A novel class of compounds with cutaneous wound healing properties.
|
Academic Article
|
PET imaging of EGFR expression in nude mice bearing MDA-MB-468, a human breast adenocarcinoma.
|
Academic Article
|
Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein.
|
Academic Article
|
Adenoviral transduction of melanoma cells with B7-1: antitumor immunity and immunosuppressive factors.
|
Academic Article
|
A novel preclinical strategy for identifying cardiotoxic kinase inhibitors and mechanisms of cardiotoxicity.
|
Academic Article
|
Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.
|
Academic Article
|
Independent regulation of growth and SMAD-mediated transcription by transforming growth factor beta in human melanoma cells.
|
Academic Article
|
Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases.
|
Academic Article
|
Integration of investigative dermatology into the global biomedical research enterprise: past, present, and future.
|
Academic Article
|
Induction of human cytomegalovirus (HCMV)-glycoprotein B (gB)-specific neutralizing antibody and phosphoprotein 65 (pp65)-specific cytotoxic T lymphocyte responses by naked DNA immunization.
|
Academic Article
|
A central role of Bcl-X(L) in the regulation of keratinocyte survival by autocrine EGFR ligands.
|
Academic Article
|
Immunotherapy of human glioma xenografts with unlabeled, 131I-, or 125I-labeled monoclonal antibody 425 to epidermal growth factor receptor.
|
Academic Article
|
Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma.
|
Academic Article
|
Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients.
|
Academic Article
|
Growth-factor-independence and invasive properties of colorectal carcinoma cells.
|
Academic Article
|
Melanoma-associated expression of vascular endothelial growth factor and its receptors FLT-1 and KDR.
|
Academic Article
|
Loss of insulin-like growth factor I receptor-dependent expression of p107 and cyclin A in cells that lack the extracellular matrix protein secreted protein acidic and rich in cysteine.
|
Academic Article
|
Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells.
|
Academic Article
|
Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine.
|
Academic Article
|
The human melanocyte system as a model for studies on tumor progression.
|
Academic Article
|
Skin toxicity of targeted cancer agents: mechanisms and intervention.
|
Academic Article
|
Skinflammation and drug toxicity--a delicate balance.
|
Academic Article
|
Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma.
|
Academic Article
|
Expression patterns of placenta growth factor in human melanocytic cell lines.
|
Academic Article
|
The EGF receptor - an essential regulator of multiple epidermal functions.
|
Academic Article
|
Epidermal growth factor receptor-dependent control of keratinocyte survival and Bcl-xL expression through a MEK-dependent pathway.
|
Academic Article
|
Matrix-independent survival of human keratinocytes through an EGF receptor/MAPK-kinase-dependent pathway.
|
Academic Article
|
Differential expression of transforming growth factors-beta1, -beta2 and -beta3 in human colon carcinoma.
|
Academic Article
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Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.
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Keratinocyte apoptosis induced by ultraviolet B radiation and CD95 ligation -- differential protection through epidermal growth factor receptor activation and Bcl-x(L) expression.
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Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3.
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Modulation of angiogenesis and tumorigenicity of human melanocytic cells by vascular endothelial growth factor and basic fibroblast growth factor.
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Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1.
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Development of invasive and growth factor-independent cell variants from primary human melanomas.
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Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes.
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Specific sequences in p120ctn determine subcellular distribution of its multiple isoforms involved in cellular adhesion of normal and malignant epithelial cells.
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Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytes.
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Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit.
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Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha.
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Expression and transcriptional regulation of caspase-14 in simple and complex epithelia.
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Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens.
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Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas.
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Radioiodinated (I-125) monoclonal antibody 425 in the treatment of high grade glioma patients: ten-year synopsis of a novel treatment.
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Regulation of intracellular pH in human melanoma: potential therapeutic implications.
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Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage.
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Tumor progression in the human melanocytic system.
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Divergent effects of two sequence variants of GJB3 (G12D and R32W) on the function of connexin 31 in vitro.
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Epidermal growth factor (EGF) and monoclonal antibody to cell surface EGF receptor bind to the same chromatin receptor.
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Inhibition of metastases of a human melanoma xenograft by monoclonal antibody to the GD2/GD3 gangliosides.
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Inhibition of cell survival and invasive potential of colorectal carcinoma cells by the tyrosine kinase inhibitor STI571.
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Extracellular matrix composition modulates cell cycle checkpoint control: a new twist to radiation sensitivity.
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Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects.
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Targeting the EGFR in neoplasia--more questions than answers.
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Radioimmunodetection of human glioma xenografts by monoclonal antibody to epidermal growth factor receptor.
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Complex regulation of signal transducers and activators of transcription 3 activation in normal and malignant keratinocytes.
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Keratinocyte culture in the absence of substrate attachment.
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Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers.
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Human pancreatic carcinoma cells secrete bioactive interleukin-18 after treatment with 5-fluorouracil: implications for anti-tumor immune response.
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Predicting the future from trials of the past: epidermal growth factor receptor expression and outcome of fractionated radiation therapy trials.
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Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids.
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E-cadherin loss promotes the initiation of squamous cell carcinoma invasion through modulation of integrin-mediated adhesion.
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Regulation of NK cell functions by TGF-beta 1.
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EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities.
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Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor-1.
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Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling.
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Use of a serum-free epidermal culture model to show deleterious effects of epidermal growth factor on morphogenesis and differentiation.
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Antisense inhibition of cyclin D1 expression is equivalent to flavopiridol for radiosensitization of zebrafish embryos.
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Cooperative induction of a tolerogenic dendritic cell phenotype by cytokines secreted by pancreatic carcinoma cells.
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Inhibition of the fibroblast growth factor receptor 1 (FGFR-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation.
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Wilms' tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma.
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Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes.
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In vivo radioprotection by the fullerene nanoparticle DF-1 as assessed in a zebrafish model.
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Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes.
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Zebrafish: an emerging model system for human disease and drug discovery.
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Anchorless keratinocyte survival: an emerging pathogenic mechanism for squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.
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Gene expression profiles as markers of aggressive disease-EGFR as a factor.
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Recessive dystrophic epidermolysis bullosa-associated squamous-cell carcinoma: an enigmatic entity with complex pathogenesis.
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Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells.
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Growth factor independence and growth regulatory pathways in human melanoma development.
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Cytokine-induced expression of transforming growth factor-alpha and the epidermal growth factor receptor in neonatal skin explants.
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Radiotoxicity of 125I-labeled monoclonal antibody 425 against cancer cells containing epidermal growth factor receptor.
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Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells.
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Autocrine/paracrine regulation of keratinocyte urokinase plasminogen activator through the TGF-alpha/EGF receptor.
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Cells expressing partially unfolded R789C/p.R989C type II procollagen mutant associated with spondyloepiphyseal dysplasia undergo apoptosis.
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Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos.
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Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425.
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Antiproliferative effects of tyrosine kinase inhibitors (tyrphostins) on human bladder and renal carcinoma cells.
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Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity.
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Biochemical and structural characterization of the Pak1-LC8 interaction.
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Skin toxicity caused by EGFR antagonists-an autoinflammatory condition triggered by deregulated IL-1 signaling?
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Identification of differentially expressed messenger RNAs in human melanocytes and melanoma cells.
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Nature's design: A blueprint for engineered therapeutic antibodies.
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Enhancement of epidermal growth factor receptor expression on glioma cells by recombinant tumor necrosis factor alpha.
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Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development.
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Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
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Nuclear factor kappaB inhibitors alleviate and the proteasome inhibitor PS-341 exacerbates radiation toxicity in zebrafish embryos.
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Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies.
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EGF-R dependent regulation of keratinocyte survival.
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Detection by monoclonal antibodies of the Wilms' tumor (WT1) nuclear protein in patients with acute leukemia.
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WT1 mutation in malignant mesothelioma and WT1 immunoreactivity in relation to p53 and growth factor receptor expression, cell-type transition, and prognosis.
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Inhibition of TGF alpha-induced second messengers by anti-EGF receptor antibody-425.
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Radiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound.
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The Triterpenoid RTA 408 is a Robust Mitigator of Hematopoietic Acute Radiation Syndrome in Mice.
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Growth and phenotypic characteristics of human nevus cells in culture.
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Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response.
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Distinct Cell Stress Responses Induced by ATP Restriction in Quiescent Human Fibroblasts.
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ß1 integrin- and JNK-dependent tumor growth upon hypofractionated radiation.
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Tumor Metabolism in the Microenvironment of Nodal Metastasis in Oral Squamous Cell Carcinoma.
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Global mapping of transcription factor motifs in human aging.
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Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin.
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Loss of CD169+ Subcapsular Macrophages during Metastatic Spread of Head and Neck Squamous Cell Carcinoma.
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Metformin Clinical Trial in HPV+ and HPV- Head and Neck Squamous Cell Carcinoma: Impact on Cancer Cell Apoptosis and Immune Infiltrate.
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Tumor-Derived Extracellular Vesicles Require ß1 Integrins to Promote Anchorage-Independent Growth.
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Effect of Hypercapnia, an Element of Obstructive Respiratory Disorders, on Pancreatic Cancer Chemoresistance and Progression.
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Is Host Metabolism the Missing Link to Improving Cancer Outcomes?
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miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas.
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Cancer-Associated Fibroblast Density, Prognostic Characteristics, and Recurrence in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis.
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Discordant Responses Between Primary Head and Neck Tumors and Nodal Metastases Treated With Neoadjuvant Nivolumab: Correlation of Radiographic and Pathologic Treatment Effect.
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Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue.
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