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Xia, Xugang

One or more keywords matched the following items that are connected to Xia, Xugang

Item Type	Name
Concept	Amyotrophic Lateral Sclerosis
Academic Article	Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.
Academic Article	FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Academic Article	Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats.
Academic Article	Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis.
Academic Article	Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo.
Academic Article	Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression.
Academic Article	Nerve injection of viral vectors efficiently transfers transgenes into motor neurons and delivers RNAi therapy against ALS.

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Motor Neuron Disease

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