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Concept
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Cell Differentiation
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Academic Article
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Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential.
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Academic Article
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Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns.
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Academic Article
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The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization.
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Academic Article
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Proposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation.
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Academic Article
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Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation.
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Academic Article
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Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytes.
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Academic Article
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Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation.
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Academic Article
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HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells.
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Academic Article
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A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis.
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Academic Article
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Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosis.
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Academic Article
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Comparative transcriptional analysis of embryoid body versus two-dimensional differentiation of murine embryonic stem cells.
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Academic Article
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Evaluation of cytokines for expansion of the megakaryocyte and granulocyte lineages.
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Academic Article
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Variations in culture pH affect the cloning efficiency and differentiation of progenitor cells in ex vivo haemopoiesis.
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Academic Article
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pH is a potent modulator of erythroid differentiation.
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Academic Article
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Physiologically significant effects of pH and oxygen tension on granulopoiesis.
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Academic Article
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Dynamic model of ex vivo granulocytic kinetics to examine the effects of oxygen tension, pH, and interleukin-3.
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Academic Article
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The lactate issue revisited: novel feeding protocols to examine inhibition of cell proliferation and glucose metabolism in hematopoietic cell cultures.
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Academic Article
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Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes.
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Academic Article
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Oxygen tension modulates the expression of cytokine receptors, transcription factors, and lineage-specific markers in cultured human megakaryocytes.
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Academic Article
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Cell density-dependent proliferation in frequently-fed peripheral blood mononuclear cell cultures.
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Academic Article
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Clinical-scale production of granulocyte progenitor and post-progenitor cells using daniplestim, leridistim, Progenipoietin, Promegapoietin and autologous plasma.
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Academic Article
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Higher pH promotes megakaryocytic maturation and apoptosis.
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