Thomas Jefferson University

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Aplin, Andrew
One or more keywords matched the following items that are connected to Aplin, Andrew
Item TypeName
Concept DNA-Binding Proteins
Concept Intermediate Filament Proteins
Concept Membrane Proteins
Concept Neoplasm Proteins
Concept Nerve Tissue Proteins
Concept Protein Synthesis Inhibitors
Concept Proto-Oncogene Proteins
Concept Recombinant Fusion Proteins
Concept Oncogene Proteins
Concept Tumor Suppressor Protein p53
Concept Proto-Oncogene Proteins c-jun
Concept Protein-Serine-Threonine Kinases
Concept Protein Structure, Tertiary
Concept Cell Cycle Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-met
Concept Proto-Oncogene Proteins c-raf
Concept Mitogen-Activated Protein Kinase 1
Concept rho GTP-Binding Proteins
Concept rhoA GTP-Binding Protein
Concept Receptor Protein-Tyrosine Kinases
Concept Mitogen-Activated Protein Kinases
Concept Mitogen-Activated Protein Kinase Kinases
Concept Tumor Suppressor Proteins
Concept Ubiquitin-Protein Ligase Complexes
Concept GTP-Binding Protein alpha Subunits, Gq-G11
Concept Ubiquitin-Protein Ligases
Concept S-Phase Kinase-Associated Proteins
Concept Protein Kinase Inhibitors
Concept Intracellular Signaling Peptides and Proteins
Concept JNK Mitogen-Activated Protein Kinases
Concept p38 Mitogen-Activated Protein Kinases
Concept Mitogen-Activated Protein Kinase 3
Concept Proto-Oncogene Proteins B-raf
Concept Adaptor Proteins, Signal Transducing
Concept Mutant Proteins
Concept ets-Domain Protein Elk-1
Concept Apoptosis Regulatory Proteins
Concept bcl-X Protein
Concept bcl-Associated Death Protein
Concept Proto-Oncogene Proteins c-akt
Concept Focal Adhesion Protein-Tyrosine Kinases
Academic Article alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.
Academic Article FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.
Academic Article The wrath of RAFs: rogue behavior of B-RAF kinase inhibitors.
Academic Article Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.
Academic Article CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.
Academic Article Mind the BAP.
Academic Article FOXD3 regulates migration properties and Rnd3 expression in melanoma cells.
Academic Article Mechanisms of resistance to RAF inhibitors in melanoma.
Academic Article Finding the root of the problem: the quest to identify melanoma stem cells.
Academic Article Axl of evil?
Academic Article Meeting report from the 2011 International Melanoma Congress, Tampa, Florida.
Academic Article The Yin-Yang of RAF inhibitors.
Academic Article Anchorage-dependent ERK signaling--mechanisms and consequences.
Academic Article Cell adhesion differentially regulates the nucleocytoplasmic distribution of active MAP kinases.
Academic Article Cell adhesion molecule regulation of nucleocytoplasmic trafficking.
Academic Article Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells.
Academic Article Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.
Academic Article Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling.
Academic Article Cyclin D3 expression in melanoma cells is regulated by adhesion-dependent phosphatidylinositol 3-kinase signaling and contributes to G1-S progression.
Academic Article Genetic and expression aberrations of E3 ubiquitin ligases in human breast cancer.
Academic Article Melanocyte receptors: clinical implications and therapeutic relevance.
Academic Article B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization.
Academic Article Skp2 regulates G2/M progression in a p53-dependent manner.
Academic Article Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensions.
Academic Article Mcl-1 is required for melanoma cell resistance to anoikis.
Academic Article Sestrin2 Protein Positively Regulates AKT Enzyme Signaling and Survival in Human Squamous Cell Carcinoma and Melanoma Cells.
Grant Targeted therapies in cutaneous melanoma
Grant FOXD3 up-regulation and ERBB3 signaling as an adaptive response to BRAF inhibitors in melanoma
Grant B-RAF Regulation of the Cell Cycle in Melanoma
Academic Article Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma.
Academic Article ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.
Academic Article Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation.
Concept Protein Domains
Academic Article Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma.
Grant Mechanisms of uveal melanoma dormancy and targeted therapy tolerance
Grant Targeting Systems Vulnerabilities in the G?q/GNAQ Oncogenic Signaling Circuitry: New Precision Therapies for Uveal Melanoma
Academic Article Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma.
Academic Article Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma.
Search Criteria
  • GTP Binding Proteins