Thomas Jefferson University

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Aplin, Andrew
One or more keywords matched the following items that are connected to Aplin, Andrew
Item TypeName
Concept Proto-Oncogene Proteins c-raf
Concept Proto-Oncogene Proteins B-raf
Academic Article alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.
Academic Article FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.
Academic Article The wrath of RAFs: rogue behavior of B-RAF kinase inhibitors.
Academic Article Akt3-mediated resistance to apoptosis in B-RAF-targeted melanoma cells.
Academic Article Hyperactivation of MEK-ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells.
Academic Article FOXD3 regulates migration properties and Rnd3 expression in melanoma cells.
Academic Article Adaptive upregulation of FOXD3 and resistance to PLX4032/4720-induced cell death in mutant B-RAF melanoma cells.
Academic Article Meeting report from the 2011 International Melanoma Congress, Tampa, Florida.
Academic Article ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity.
Academic Article The Yin-Yang of RAF inhibitors.
Academic Article Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases.
Academic Article Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells.
Academic Article Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling.
Academic Article B-RAF and PI-3 kinase signaling protect melanoma cells from anoikis.
Academic Article Cyclin D3 expression in melanoma cells is regulated by adhesion-dependent phosphatidylinositol 3-kinase signaling and contributes to G1-S progression.
Academic Article Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells.
Academic Article B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization.
Academic Article Mutant B-RAF mediates resistance to anoikis via Bad and Bim.
Academic Article Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensions.
Academic Article Mcl-1 is required for melanoma cell resistance to anoikis.
Academic Article ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.
Academic Article Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma.
Academic Article FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma.
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  • Proto Oncogene Proteins A raf