Item Type | Name |
Concept
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Cells, Cultured
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Concept
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Tumor Cells, Cultured
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Academic Article
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Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells.
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Academic Article
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The AIM2 inflammasome is critical for innate immunity to Francisella tularensis.
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Academic Article
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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
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Academic Article
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Retroviral transfer of CPP32beta gene into malignant gliomas in vitro and in vivo.
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Academic Article
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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.
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Academic Article
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Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis.
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Academic Article
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Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance.
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Academic Article
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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.
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Academic Article
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Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.
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Academic Article
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E1A-induced processing of procaspase-8 can occur independently of FADD and is inhibited by Bcl-2.
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Academic Article
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Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells.
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Academic Article
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Calpain activation is upstream of caspases in radiation-induced apoptosis.
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Academic Article
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Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis.
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Academic Article
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Involvement of BCL-2 in glucocorticoid-induced apoptosis of human pre-B-leukemias.
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Academic Article
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Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.
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Academic Article
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B cell apoptosis triggered by antigen receptor ligation proceeds via a novel caspase-dependent pathway.
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Academic Article
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Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1.
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Academic Article
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TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis.
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Academic Article
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Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway.
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Academic Article
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vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma.
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Academic Article
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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.
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Academic Article
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Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells.
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Academic Article
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FGF induces a switch in death receptor pathways in neuronal cells.
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Academic Article
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Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter.
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Academic Article
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c-IAP1 blocks TNFalpha-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells.
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Academic Article
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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.
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Academic Article
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sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein.
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Academic Article
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CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.
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Academic Article
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Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria.
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Academic Article
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Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC.
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Academic Article
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The PYRIN-CARD protein ASC is an activating adaptor for caspase-1.
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Academic Article
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Expression and transcriptional regulation of caspase-14 in simple and complex epithelia.
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Academic Article
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Role of Smac in human leukaemic cell apoptosis and proliferation.
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Academic Article
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The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein.
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Academic Article
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Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice.
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Academic Article
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Modulator inhibits nuclear translocation of the glucocorticoid receptor and inhibits glucocorticoid-induced apoptosis in the human leukemic cell line CEM C-7.
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Academic Article
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Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities.
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Academic Article
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Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter.
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Academic Article
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Assembly, purification, and assay of the activity of the ASC pyroptosome.
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Academic Article
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DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis.
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Academic Article
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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
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Academic Article
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Activation of the CPP32 protease in apoptosis induced by 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents.
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Academic Article
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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
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Academic Article
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Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis.
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Academic Article
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Baculovirus P35 inhibits the glucocorticoid-mediated pathway of cell death.
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Academic Article
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Activation of CPP32 and Mch3 alpha in wild-type p53-induced apoptosis.
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Academic Article
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FLIP is expressed in mouse testis and protects germ cells from apoptosis.
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Academic Article
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Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.
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Academic Article
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Resistance of actin to cleavage during apoptosis.
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Academic Article
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Synthetic peptide sequence from the C-terminus of the insulin-like growth factor-I receptor that induces apoptosis and inhibition of tumor growth.
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Academic Article
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Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells.
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Academic Article
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Heteronuclear ribonucleoproteins C1 and C2, components of the spliceosome, are specific targets of interleukin 1beta-converting enzyme-like proteases in apoptosis.
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Academic Article
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Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP.
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