Thomas Jefferson University

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Shapiro, Irving
One or more keywords matched the following items that are connected to Shapiro, Irving
Item TypeName
Concept Cells, Cultured
Concept Tumor Cells, Cultured
Academic Article Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling.
Academic Article Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc.
Academic Article Antibacterial activity of bone allografts: comparison of a new vancomycin-tethered allograft with allograft loaded with adsorbed vancomycin.
Academic Article Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease.
Academic Article Transforming growth factor ? controls CCN3 expression in nucleus pulposus cells of the intervertebral disc.
Academic Article Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1a degradation.
Academic Article Developmental expression of creatine kinase isoenzymes in chicken growth cartilage.
Academic Article Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-a (TNF-a) on cells of the nucleus pulposus through co-activation of nuclear factor ?B (NF-?B)/p65 signaling.
Academic Article Matrix regulation of skeletal cell apoptosis II: role of Arg-Gly-Asp-containing peptides.
Academic Article Maturation-dependent thiol loss increases chondrocyte susceptibility to apoptosis.
Academic Article Detection of apoptotic gene expression in human osteoblast-like cells by cDNA microarrays.
Academic Article Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy.
Academic Article Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal.
Academic Article Nitric oxide-nitric oxide synthase regulates key maturational events during chondrocyte terminal differentiation.
Academic Article Cellular therapy for disc degeneration.
Academic Article Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival.
Academic Article Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.
Academic Article Development of the terminally differentiated state sensitizes epiphyseal chondrocytes to apoptosis through caspase-3 activation.
Academic Article Development of a tissue-engineered bypass graft seeded with stem cells.
Academic Article Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro: implications for cell-based transplantation therapy.
Academic Article Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling.
Academic Article Evidence for skeletal progenitor cells in the degenerate human intervertebral disc.
Academic Article Hypoxic induction of UCP3 in the growth plate: UCP3 suppresses chondrocyte autophagy.
Academic Article SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc.
Academic Article Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc.
Academic Article Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc.
Academic Article Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy.
Academic Article PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.
Academic Article Endothelial differentiation of adipose-derived stem cells: effects of endothelial cell growth supplement and shear force.
Academic Article Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor a and IL-1? in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.
Academic Article Prolyl-4-hydroxylase domain protein 2 controls NF-?B/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
Academic Article The Proteasome Inhibitor Carfilzomib Suppresses Parathyroid Hormone-induced Osteoclastogenesis through a RANKL-mediated Signaling Pathway.
Academic Article TGF? regulates Galectin-3 expression through canonical Smad3 signaling pathway in nucleus pulposus cells: implications in intervertebral disc degeneration.
Academic Article Class I and IIa HDACs Mediate HIF-1a Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1a Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
Academic Article Circadian factors BMAL1 and RORa control HIF-1a transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health.
Academic Article Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death.
Academic Article COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells.
Academic Article Tendinosis develops from age- and oxygen tension-dependent modulation of Rac1 activity.
Academic Article Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation.
Academic Article Creatine kinase activity is required for mineral deposition and matrix synthesis in endochondral growth cartilage.
Academic Article Effects of deferoximine on chondrocyte alkaline phosphatase activity: proxidant role of deferoximine in thalassemia.
Academic Article Induction of apoptosis in human T-cells by organomercuric compounds: a flow cytometric analysis.
Academic Article Inorganic phosphate induces apoptosis of osteoblast-like cells in culture.
Academic Article Induction of apoptosis in human T-cells by methyl mercury: temporal relationship between mitochondrial dysfunction and loss of reductive reserve.
Academic Article Induction of apoptosis in skeletal tissues: phosphate-mediated chick chondrocyte apoptosis is calcium dependent.
Academic Article Phosphate ions mediate chondrocyte apoptosis through a plasma membrane transporter mechanism.
Academic Article Ascorbic acid regulates multiple metabolic activities of cartilage cells.
Academic Article Induction of chondrocyte vesiculation in vitro.
Academic Article Retinoic acid is a major regulator of chondrocyte maturation and matrix mineralization.
Academic Article Phosphate-induced chondrocyte apoptosis is linked to nitric oxide generation.
Academic Article Effect of varying physical properties of porous, surface modified bioactive glass 45S5 on osteoblast proliferation and maturation.
Academic Article Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism.
Academic Article Population kinetics of cells in tissue culture incubated at low temperature.
Academic Article Retinoic acid induces rapid mineralization and expression of mineralization-related genes in chondrocytes.
Academic Article Matrix regulation of skeletal cell apoptosis. Role of calcium and phosphate ions.
Academic Article Mechanism of action of beta-glycerophosphate on bone cell mineralization.
Academic Article Mechanisms by which extracellular matrix components induce osteoblast apoptosis.
Academic Article Bioactive material template for in vitro synthesis of bone.
Academic Article Computer modeling of the oxygen supply and demand of cells of the avian growth cartilage.
Academic Article Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb.
Academic Article Inhibition of poly(ADP-ribose) polymerase rescues human T lymphocytes from methylmercury-induced apoptosis.
Academic Article The effect of simulated microgravity on osteoblasts is independent of the induction of apoptosis.
Academic Article Retinoic acid induces a shift in the energetic state of hypertrophic chondrocytes.
Academic Article Bioactive glass serves as a substrate for maintenance of phenotype of nucleus pulposus cells of the intervertebral disc.
Academic Article Developmental regulation of creatine kinase activity in cells of the epiphyseal growth cartilage.
Academic Article Mercuric chloride induces apoptosis in human T lymphocytes: evidence of mitochondrial dysfunction.
Academic Article Changes in osteonectin distribution and levels are associated with mineralization of the chicken tibial growth cartilage.
Academic Article A rapid and ultrasensitive method for measurement of DNA, calcium and protein content, and alkaline phosphatase activity of chondrocyte cultures.
Academic Article Regulated production of mineralization-competent matrix vesicles in hypertrophic chondrocytes.
Academic Article Si-Ca-P xerogels and bone morphogenetic protein act synergistically on rat stromal marrow cell differentiation in vitro.
Academic Article Retinoic acid modulation of glutathione and cysteine metabolism in chondrocytes.
Academic Article Adenine nucleotide metabolism by chondrocytes in vitro: role of ATP in chondrocyte maturation and matrix mineralization.
Academic Article Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?
Academic Article Extracellular phosphate ions cause apoptosis of terminally differentiated epiphyseal chondrocytes.
Academic Article Extracellular ATP modulates [Ca2+]i in retinoic acid-treated embryonic chondrocytes.
Academic Article Cell hypertrophy and type X collagen synthesis in cultured articular chondrocytes.
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