Thomas Jefferson University

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Shapiro, Irving
One or more keywords matched the following items that are connected to Shapiro, Irving
Item TypeName
Concept Rats, Inbred F344
Concept Rats, Inbred Strains
Concept Rats, Wistar
Concept Rats
Academic Article Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling.
Academic Article Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc.
Academic Article Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease.
Academic Article Hypoxic regulation of ß-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins.
Academic Article Bone cell autophagy is regulated by environmental factors.
Academic Article TNF-a and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.
Academic Article HIF-1a and HIF-2a degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc.
Academic Article Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1a degradation.
Academic Article Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1a activity in hypoxia.
Academic Article Smad3 controls ß-1,3-glucuronosyltransferase 1 expression in rat nucleus pulposus cells: implications of dysregulated expression in disc disease.
Academic Article Matrix regulation of skeletal cell apoptosis II: role of Arg-Gly-Asp-containing peptides.
Academic Article Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2.
Academic Article An organ culture system for the study of the nucleus pulposus: description of the system and evaluation of the cells.
Academic Article Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy.
Academic Article Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal.
Academic Article Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival.
Academic Article Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.
Academic Article Toward an optimum system for intervertebral disc organ culture: TGF-beta 3 enhances nucleus pulposus and anulus fibrosus survival and function through modulation of TGF-beta-R expression and ERK signaling.
Academic Article TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc.
Academic Article Galectin-3 expression in the intervertebral disc: a useful marker of the notochord phenotype?
Academic Article In situ oxygen utilization in the rat intervertebral disc.
Academic Article MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP.
Academic Article Vancomycin covalently bonded to titanium alloy prevents bacterial colonization.
Academic Article Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.
Academic Article Vancomycin bound to Ti rods reduces periprosthetic infection: preliminary study.
Academic Article HIF-1 alpha is a regulator of galectin-3 expression in the intervertebral disc.
Academic Article Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling.
Academic Article Evidence for skeletal progenitor cells in the degenerate human intervertebral disc.
Academic Article SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc.
Academic Article Micro-CT analysis with multiple thresholds allows detection of bone formation and resorption during ultrasound-treated fracture healing.
Academic Article Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc.
Academic Article Controlled release of vancomycin from thin sol-gel films on implant surfaces successfully controls osteomyelitis.
Academic Article Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc.
Academic Article Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc.
Academic Article PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.
Academic Article Reversine enhances generation of progenitor-like cells by dedifferentiation of annulus fibrosus cells.
Academic Article BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs.
Grant Disruption of Osmoregulation Promotes Degenerative Disc Disease
Academic Article TNF-a promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells.
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