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Benovic, Jeffrey
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Item TypeName
Concept Amino Acid Sequence
Concept Animals
Concept Base Sequence
Concept Camelids, New World
Concept Cattle
Concept Cell Adhesion
Concept Cell Cycle
Concept Cell Differentiation
Concept Cell Division
Concept Cell Line
Concept Cell Membrane
Concept Cell Movement
Concept Cell Nucleus
Concept Cells, Cultured
Concept Cercopithecus aethiops
Concept Chemoreceptor Cells
Concept Coated Pits, Cell-Membrane
Concept Drosophila
Concept Enzyme-Linked Immunosorbent Assay
Concept Epithelial Cells
Concept Genetic Vectors
Concept Guinea Pigs
Concept Cricetinae
Concept HeLa Cells
Concept Humans
Concept Levodopa
Concept Ligands
Concept Lipids
Concept Lipopolysaccharides
Concept Longevity
Concept Luminescent Proteins
Concept Lysine
Concept Lysosomes
Concept Mammals
Concept Molecular Sequence Data
Concept Phylogeny
Concept Receptors, Cell Surface
Concept Saccharomyces cerevisiae
Concept Bombyx
Concept Tumor Cells, Cultured
Concept CHO Cells
Concept PC12 Cells
Concept Caenorhabditis elegans
Concept Rats, Sprague-Dawley
Concept Leukotriene D4
Concept Receptors, Leukotriene
Concept Cell Cycle Proteins
Concept HL-60 Cells
Concept Cell Lineage
Concept COS Cells
Concept K562 Cells
Concept Animals, Genetically Modified
Concept Endothelial Cells
Concept Ubiquitin-Protein Ligases
Concept Cell Line, Tumor
Concept Lactams, Macrocyclic
Concept Cell Growth Processes
Concept Receptors, Lysophospholipid
Concept Receptors, Lysosphingolipid
Concept Insulin-Secreting Cells
Concept Mice
Concept Rats
Concept Molecular Dynamics Simulation
Concept HEK293 Cells
Academic Article Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.
Academic Article Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function.
Academic Article Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity.
Academic Article Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.
Academic Article Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but ß-arrestin-independent pathways.
Academic Article Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.
Academic Article Differential expression of arrestins is a predictor of breast cancer progression and survival.
Academic Article G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.
Academic Article Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth.
Academic Article G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression.
Academic Article Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo.
Academic Article G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition.
Academic Article Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic Acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.
Academic Article G-protein-coupled receptors signal victory.
Academic Article G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation.
Academic Article Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking.
Academic Article Characterization of G protein-coupled receptor kinases.
Academic Article Characterization of arrestin expression and function.
Academic Article Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
Academic Article Regulation of arrestin-3 phosphorylation by casein kinase II.
Academic Article Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking.
Academic Article The third intracellular loop of alpha 2-adrenergic receptors determines subtype specificity of arrestin interaction.
Academic Article Phosphorylation-independent desensitization of G protein-coupled receptors?
Academic Article G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits.
Academic Article The ins and outs of G protein-coupled receptor trafficking.
Academic Article Differential interaction of GRK2 with members of the G alpha q family.
Academic Article Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation.
Academic Article Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins.
Academic Article G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation.
Academic Article The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4.
Academic Article Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin.
Academic Article A predicted amphipathic helix mediates plasma membrane localization of GRK5.
Academic Article Characterization of the GRK2 binding site of Galphaq.
Academic Article Analysis of G-protein-coupled receptor kinase RGS homology domains.
Academic Article A new key in breast cancer metastasis.
Academic Article Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2.
Academic Article Arrestin2 expression selectively increases during neural differentiation.
Academic Article Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling.
Academic Article Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2.
Academic Article P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.
Academic Article Caenorhabditus elegans arrestin regulates neural G protein signaling and olfactory adaptation and recovery.
Academic Article Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3.
Academic Article Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding.
Academic Article The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.
Academic Article Distinct clathrin-coated pits sort different G protein-coupled receptor cargo.
Academic Article Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages.
Academic Article Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A.
Academic Article Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.
Academic Article Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
Academic Article M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms.
Academic Article beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation.
Academic Article Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori.
Academic Article Effects of inflammation and acute beta-agonist inhalation on beta 2-AR signaling in human airways.
Academic Article Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer.
Academic Article Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2.
Academic Article Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
Academic Article G-protein-coupled-receptor kinases mediate TNFa-induced NF?B signalling via direct interaction with and phosphorylation of I?Ba.
Academic Article Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein.
Academic Article Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors.
Academic Article Call for Papers! A Special Thematic Compilation/Special Issue Crossover with ACS Chemical Biology, ACS Medicinal Chemistry Letters, and the Journal of Medicinal Chemistry Focused on New Frontiers in Kinases.
Academic Article Role of ß-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking.
Academic Article Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.
Academic Article Consequence of the tumor-associated conversion to cyclin D1b.
Academic Article Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms.
Academic Article c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.
Grant Training Program in Cellular, Biochemical, and Molecular Sciences
Grant Role of Arrestins in G Protein-Coupled Receptor Regulation
Grant GRC on Second Messengers &Protein Phosphorylation
Grant Short-term Training Students in Health Professional Sch.
Grant ARRESTINS IN G PROTEIN-COUPLE RECEPTOR REGULATION
Grant BETA-ADRENERGIC RECEPTOR REGULATION IN AIRWAY EPITHELIUM
Grant Training Program in Biomolecular Signal Transduction
Grant Arestin Interaction with Endocytic Components
Grant G Protein-Coupled Receptor Kinases
Grant Regulation of CXCR4 Signaling
Academic Article Structural and Functional Analysis of a ß2-Adrenergic Receptor Complex with GRK5.
Academic Article G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of ß-Arrestin.
Academic Article G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans.
Academic Article Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma.
Grant Characterization of beta-arrestin-biased beta 2-adrenergic receptor signaling in cardiovascular function
Grant Regulation of G protein-coupled receptor signaling and trafficking
Academic Article G protein-coupled receptor kinases: Past, present and future.
Grant Structural and dynamic analysis of GRK interaction with G protein-coupled receptors
Academic Article Pepducins as a potential treatment strategy for asthma and COPD.
Academic Article Pepducin-mediated cardioprotection via ß-arrestin-biased ß2-adrenergic receptor-specific signaling.
Academic Article Effects of Oncogenic Gaq and Ga11 Inhibition by FR900359 in Uveal Melanoma.
Academic Article G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel.
Academic Article GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets.
Academic Article Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting.
Academic Article Biased agonism at ß-adrenergic receptors.
Academic Article Historical Perspective of the G Protein-Coupled Receptor Kinase Family.
Academic Article Phenylalanine 193 in Extracellular Loop 2 of the ß2-Adrenergic Receptor Coordinates ß-Arrestin Interaction.
Academic Article Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4.
Academic Article Pepducin ICL1-9-Mediated ß2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner.
Academic Article Targeting Oncogenic Gaq/11 in Uveal Melanoma.
Academic Article Hypergastrinemia, a clue leading to the identification of an atypical form of diabetes mellitus type 2.
Academic Article ß-agonist profiling reveals biased signalling phenotypes for the ß2 -adrenergic receptor with possible implications for the treatment of asthma.
Academic Article IGF1R Inhibition Enhances the Therapeutic Effects of Gq/11 Inhibition in Metastatic Uveal Melanoma Progression.
Academic Article PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells.
Academic Article G protein-coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin.
Academic Article Identification of a ?-arrestin-biased negative allosteric modulator for the ?2-adrenergic receptor.
Academic Article Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma.
Academic Article How carvedilol does not activate ?2-adrenoceptors.
Academic Article The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic ?-Cell Function and Diabetes.
Academic Article Diverse pathways in GPCR-mediated activation of Ca2+ mobilization in HEK293 cells.
Academic Article Cloning of the cDNA and genes for the hamster and human beta 2-adrenergic receptors.
Academic Article Purification and characterization of beta-adrenergic receptor kinase.
Academic Article Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein).
Academic Article Comparison of R-, S-, and RS-albuterol interaction with human beta 1- and beta 2-adrenergic receptors.
Academic Article Receptor docking sites for G-protein betagamma subunits. Implications for signal regulation.
Academic Article The beta-adrenergic receptor kinase (GRK2) is regulated by phospholipids.
Academic Article Chronic effects of catecholamines on the beta 2-adrenoreceptor system in cultured human airway epithelial cells.
Academic Article Rapid agonist-induced desensitization and internalization of the A(2B) adenosine receptor is mediated by a serine residue close to the COOH terminus.
Academic Article Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells.
Academic Article Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase.
Academic Article Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain.
Academic Article Modulation by GM1 ganglioside of beta 1-adrenergic receptor-induced cyclic AMP formation in Sf9 cells.
Academic Article Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors.
Academic Article Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family.
Academic Article Molecular mechanisms of beta-adrenergic receptor desensitization.
Academic Article G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells.
Academic Article G-protein-coupled receptor kinase activity is increased in hypertension.
Academic Article Expression and function of the beta-adrenergic receptor coupled-adenylyl cyclase system on human airway epithelial cells.
Academic Article U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation.
Academic Article Homogeneous substrate-labeled fluorescent immunoassay for theophylline in serum.
Academic Article Safe use of the CXCR4 inhibitor ALX40-4C in humans.
Academic Article beta-Arrestin: a protein that regulates beta-adrenergic receptor function.
Academic Article Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking.
Academic Article Mechanism of quenching of phototransduction. Binding competition between arrestin and transducin for phosphorhodopsin.
Academic Article Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles.
Academic Article Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin.
Academic Article Mechanism of beta-adrenergic receptor kinase activation by G proteins.
Academic Article Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling.
Academic Article Arrestin specificity for G protein-coupled receptors in human airway smooth muscle.
Academic Article Altered activity of palmitoylation-deficient and isoprenylated forms of the G protein-coupled receptor kinase GRK6.
Academic Article Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.
Academic Article Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells.
Academic Article Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus.
Academic Article Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.
Academic Article Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5.
Academic Article Visual arrestin interaction with rhodopsin. Sequential multisite binding ensures strict selectivity toward light-activated phosphorylated rhodopsin.
Academic Article Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine.
Academic Article Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5.
Academic Article Characterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanisms.
Academic Article Role of the differentially spliced carboxyl terminus in thromboxane A2 receptor trafficking: identification of a distinct motif for tonic internalization.
Academic Article Control of the cardiac muscarinic K+ channel by beta-arrestin 2.
Academic Article Regulation of adenylyl cyclase-coupled beta-adrenergic receptors.
Academic Article Internalization of the m2 muscarinic acetylcholine receptor. Arrestin-independent and -dependent pathways.
Academic Article Coupling of M2 muscarinic receptors to membrane ion channels via phosphoinositide 3-kinase gamma and atypical protein kinase C.
Academic Article Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase.
Academic Article Pure beta-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase.
Academic Article Agonist-receptor-arrestin, an alternative ternary complex with high agonist affinity.
Academic Article Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization.
Academic Article cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase.
Academic Article Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium.
Academic Article Expression, purification, and characterization of the G protein-coupled receptor kinase GRK6.
Academic Article MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation.
Academic Article Location of the allosteric site for 2,3-bisphosphoglycerate on human oxy- and deoxyhemoglobin as observed by magnetic resonance spectroscopy.
Academic Article Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.
Academic Article Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.
Academic Article Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking.
Academic Article Role of arrestins in G-protein-coupled receptor endocytosis.
Academic Article Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein.
Academic Article Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.
Academic Article Phosphorylation of cell surface receptors: a mechanism for regulating signal transduction pathways.
Academic Article Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles.
Academic Article Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.
Academic Article Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.
Academic Article The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2.
Academic Article Cell-free expression of visual arrestin. Truncation mutagenesis identifies multiple domains involved in rhodopsin interaction.
Academic Article Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors.
Academic Article Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting.
Academic Article Cloning and expression of GRK5: a member of the G protein-coupled receptor kinase family.
Academic Article Visual arrestin binding to rhodopsin. Intramolecular interaction between the basic N terminus and acidic C terminus of arrestin may regulate binding selectivity.
Academic Article Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A2A adenosine receptors to agonist-induced desensitization.
Academic Article G-protein-coupled receptor kinase expression in hypertension.
Academic Article Photoaffinity labelling of mammalian beta-adrenergic receptors: metal-dependent proteolysis explains apparent heterogeneity.
Academic Article Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle.
Academic Article Multiple mechanisms involving protein phosphorylation are linked to desensitization of muscarinic receptors.
Academic Article Beta-adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation.
Academic Article Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart.
Academic Article Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit.
Academic Article Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.
Academic Article G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits.
Academic Article Arrestin: mutagenesis, expression, purification, and functional characterization.
Academic Article Cyclic phosphorylation-dephosphorylation of rhodopsin in retina by protein kinase FA (the activator of ATP.Mg-dependent protein phosphatase).
Academic Article beta-Adrenergic receptor kinase. Activity of partial agonists for stimulation of adenylate cyclase correlates with ability to promote receptor phosphorylation.
Academic Article Differentially regulated expression of the G-protein-coupled receptor kinases, betaARK and GRK6, during myelomonocytic cell development in vitro.
Academic Article Regulation of G protein-coupled receptor kinases by caveolin.
Academic Article The determination of the free magnesium level in the human red blood cell by 31P NMR.
Academic Article Binding and phosphorylation of tubulin by G protein-coupled receptor kinases.
Academic Article Molecular events associated with the regulation of signaling by M2 muscarinic receptors.
Academic Article Molecular basis for subtype-specific desensitization of inhibitory adenosine receptors. Analysis of a chimeric A1-A3 adenosine receptor.
Academic Article Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
Academic Article Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.
Academic Article Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C.
Academic Article Structural determinants in the second intracellular loop of the human cannabinoid CB1 receptor mediate selective coupling to G(s) and G(i).
Academic Article Somatostatin induces translocation of the beta-adrenergic receptor kinase and desensitizes somatostatin receptors in S49 lymphoma cells.
Academic Article Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization.
Academic Article Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle.
Academic Article Regulation of G protein-coupled receptors by receptor kinases and arrestins.
Academic Article Arrestin-independent internalization of the m1, m3, and m4 subtypes of muscarinic cholinergic receptors.
Academic Article Arrestin with a single amino acid substitution quenches light-activated rhodopsin in a phosphorylation-independent fashion.
Academic Article The mammalian beta-adrenergic receptor: structural and functional characterization of the carbohydrate moiety.
Academic Article Agonist-dependent phosphorylation of human muscarinic receptors in Spodoptera frugiperda insect cell membranes by G protein-coupled receptor kinases.
Academic Article Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the beta-adrenergic receptor kinase.
Academic Article Modulation of the arrestin-clathrin interaction in cells. Characterization of beta-arrestin dominant-negative mutants.
Academic Article Phosphorylation of chick heart muscarinic cholinergic receptors by the beta-adrenergic receptor kinase.
Academic Article Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.
Academic Article Regulation of transmembrane signaling by receptor phosphorylation.
Academic Article Signaling and phosphorylation-impaired mutants of the rat follitropin receptor reveal an activation- and phosphorylation-independent but arrestin-dependent pathway for internalization.
Academic Article Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation.
Academic Article Regulation of G protein-coupled receptor kinases.
Academic Article Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
Academic Article Inhibition of the beta-adrenergic receptor kinase by polyanions.
Academic Article Molecular biology of adrenergic receptors.
Academic Article Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding.
Academic Article The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein.
Academic Article Pharmacological inhibition of protein kinases in intact cells: antagonism of beta adrenergic receptor ligand binding by H-89 reveals limitations of usefulness.
Academic Article Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein.
Academic Article Biochemical characterization of the adrenergic receptors: affinity labeling, purification, and reconstitution studies.
Academic Article Interaction of arrestins with intracellular domains of muscarinic and alpha2-adrenergic receptors.
Academic Article Serum theophylline determination by fluorescence polarization immunoassay utilizing an umbelliferone derivative as a fluorescent label.
Academic Article Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors.
Academic Article Selective reduction in A2 adenosine receptor desensitization following antisense-induced suppression of G protein-coupled receptor kinase 2 expression.
Academic Article G-Protein-coupled receptor kinase activity in hypertension : increased vascular and lymphocyte G-protein receptor kinase-2 protein expression.
Academic Article Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors.
Academic Article Dephosphorylation of the beta 2-adrenergic receptor and rhodopsin by latent phosphatase 2.
Academic Article Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation.
Academic Article Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells.
Academic Article Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin.
Academic Article Mechanisms involved in adrenergic receptor desensitization.
Academic Article Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.
Academic Article The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis.
Academic Article Role of clathrin-mediated endocytosis in agonist-induced down-regulation of the beta2-adrenergic receptor.
Academic Article A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization.
Academic Article L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain.
Academic Article The mammalian beta 2-adrenergic receptor: purification and characterization.
Academic Article Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2.
Academic Article Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes.
Academic Article Mechanisms of acute desensitization of the beta2AR-adenylyl cyclase pathway in human airway smooth muscle.
Academic Article The mammalian beta 2-adrenergic receptor: reconstitution of functional interactions between pure receptor and pure stimulatory nucleotide binding protein of the adenylate cyclase system.
Academic Article Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms.
Academic Article Purification and characterization of the beta-adrenergic receptor kinase.
Academic Article Mechanisms of agonist-induced down-regulation of the human kappa-opioid receptor: internalization is required for down-regulation.
Academic Article Polypeptide variants of beta-arrestin and arrestin3.
Academic Article Role of G protein-coupled receptor kinases on the agonist-induced phosphorylation and internalization of the follitropin receptor.
Academic Article A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the beta 2-adrenergic receptor.
Academic Article Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor. Evidence for a G-protein-coupled receptor kinase-mediated mechanism.
Academic Article Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels.
Academic Article Interleukins impair beta-adrenergic receptor adenylate cyclase (beta AR-AC) system function in human airway epithelial cells.
Academic Article Role of acidic amino acids in peptide substrates of the beta-adrenergic receptor kinase and rhodopsin kinase.
Academic Article Arrestin2 and arrestin3 are differentially expressed in the rat brain during postnatal development.
Academic Article Lipid-mediated regulation of G protein-coupled receptor kinases 2 and 3.
Academic Article Beta-adrenergic receptor kinase-1 acutely regulates PTH/PTHrP receptor signalling in human osteoblastlike cells.
Academic Article The role of G-protein coupled receptor kinases in the regulation of muscarinic cholinergic receptors.
Academic Article Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors.
Academic Article Beta-adrenergic receptor kinase: primary structure delineates a multigene family.
Academic Article Phosphorylation of the N-formyl peptide receptor carboxyl terminus by the G protein-coupled receptor kinase, GRK2.
Academic Article Association of the regulatory beta-adrenergic receptor kinase with rat liver microsomal membranes.
Academic Article A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes.
Academic Article Expression of the beta-adrenergic receptor-adenylylcyclase system in basal and columnar airway epithelial cells.
Academic Article Structure and function of the third intracellular loop of the 5-hydroxytryptamine2A receptor: the third intracellular loop is alpha-helical and binds purified arrestins.
Academic Article The beta-adrenergic receptor kinase: role in homologous desensitization in S49 lymphoma cells.
Academic Article High affinity binding of beta-adrenergic receptor kinase to microsomal membranes. Modulation of the activity of bound kinase by heterotrimeric G protein activation.
Academic Article Localization of the sites for Ca2+-binding proteins on G protein-coupled receptor kinases.
Academic Article Regulation of G protein-coupled receptors by agonist-dependent phosphorylation.
Academic Article A technique to harvest viable tracheobronchial epithelial cells from living human donors.
Academic Article Identification and chromosomal localization of a processed pseudogene of human GRK6.
Academic Article Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor.
Academic Article Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor.
Academic Article Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor.
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