Thomas Jefferson University

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Benovic, Jeffrey
One or more keywords matched the following properties of Benovic, Jeffrey
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phone 215-503-4607
One or more keywords matched the following items that are connected to Benovic, Jeffrey
Item TypeName
Concept Cyclic AMP
Concept Adenosine Triphosphatases
Concept Pentanols
Concept Amino Acid Sequence
Concept Antibodies, Monoclonal
Concept Asthma
Concept Base Sequence
Concept Benzaldehydes
Concept Cations, Divalent
Concept Cell Division
Concept Cell Nucleus
Concept Cercopithecus aethiops
Concept Chemotaxis
Concept Corpus Striatum
Concept Cytoplasm
Concept Diabetes Mellitus, Type 2
Concept Diacetyl
Concept Electrophoresis, Polyacrylamide Gel
Concept Endocytosis
Concept Epithelial Cells
Concept Fluorescent Antibody Technique
Concept Glioblastoma
Concept Glucocorticoids
Concept Glucose
Concept HeLa Cells
Concept Humans
Concept Hydroxyindoleacetic Acid
Concept Immune Sera
Concept Immunohistochemistry
Concept Inositol Phosphates
Concept Insect Hormones
Concept Insulin
Concept Levodopa
Concept Ligands
Concept Lipopolysaccharides
Concept Lysine
Concept Lysosomes
Concept Magnesium
Concept Melanoma
Concept Microscopy, Electron
Concept Microscopy, Fluorescence
Concept Microtubules
Concept Molecular Sequence Data
Concept Muscle Contraction
Concept Olfactory Pathways
Concept Pergolide
Concept Phosphatidylethanolamines
Concept Phytic Acid
Concept Precipitin Tests
Concept Proinsulin
Concept Prostatic Neoplasms
Concept Pyrrolidonecarboxylic Acid
Concept Receptors, Adrenergic
Concept Receptors, Adrenergic, beta
Concept Receptors, Androgen
Concept Receptors, Cell Surface
Concept Receptors, Histamine H1
Concept Receptors, Nicotinic
Concept Endosomes
Concept RNA, Messenger
Concept Serotonin
Concept Stereoisomerism
Concept Substantia Nigra
Concept Tetradecanoylphorbol Acetate
Concept Tumor Necrosis Factor-alpha
Concept Immunoblotting
Concept Blotting, Northern
Concept Blotting, Western
Concept Survival Rate
Concept Transforming Growth Factor beta
Concept Mutagenesis, Site-Directed
Concept CHO Cells
Concept Caenorhabditis elegans
Concept In Situ Hybridization
Concept Prostate-Specific Antigen
Concept Receptor, IGF Type 1
Concept Cyclic AMP-Dependent Protein Kinases
Concept DNA Primers
Concept Leukotriene D4
Concept Receptors, Glucagon
Concept Receptors, Purinergic P2
Concept DNA, Complementary
Concept Receptors, Leukotriene
Concept Receptors, Adrenergic, alpha-2
Concept Receptors, Adrenergic, beta-2
Concept Centrosome
Concept Receptor, ErbB-2
Concept Oncogene Proteins v-erbB
Concept HL-60 Cells
Concept GTP-Binding Proteins
Concept GTP-Binding Protein alpha Subunits, Gi-Go
Concept Arrestins
Concept Arrestin
Concept Calcineurin
Concept Receptors, CXCR4
Concept Mitogen-Activated Protein Kinase 1
Concept K562 Cells
Concept GTP Phosphohydrolases
Concept Guanine Nucleotide Exchange Factors
Concept I-kappa B Proteins
Concept RGS Proteins
Concept rac1 GTP-Binding Protein
Concept MAP Kinase Signaling System
Concept Heterotrimeric GTP-Binding Proteins
Concept Transport Vesicles
Concept Electrophoretic Mobility Shift Assay
Concept Drosophila Proteins
Concept Caenorhabditis elegans Proteins
Concept Dynamins
Concept RNA, Small Interfering
Concept Pertussis Toxin
Concept Endothelial Cells
Concept Receptors, G-Protein-Coupled
Concept Receptor, Muscarinic M2
Concept Receptor, Muscarinic M3
Concept GTP-Binding Protein alpha Subunits, Gq-G11
Concept Receptors, Serotonin, 5-HT2
Concept GTP-Binding Protein alpha Subunits
Concept GTP-Binding Protein beta Subunits
Concept GTP-Binding Protein gamma Subunits
Concept Receptors, Serotonin, 5-HT4
Concept Ubiquitin-Protein Ligases
Concept Antibodies, Phospho-Specific
Concept Casein Kinase II
Concept Immunoprecipitation
Concept Extracellular Signal-Regulated MAP Kinases
Concept Mitogen-Activated Protein Kinase 3
Concept Cell Growth Processes
Concept Receptors, Lysophospholipid
Concept Receptors, Lysosphingolipid
Concept Proto-Oncogene Proteins c-akt
Concept PTEN Phosphohydrolase
Concept I-kappa B Kinase
Concept beta-Adrenergic Receptor Kinases
Concept Proto-Oncogene Proteins c-mdm2
Concept G-Protein-Coupled Receptor Kinases
Concept G-Protein-Coupled Receptor Kinase 2
Concept G-Protein-Coupled Receptor Kinase 3
Concept G-Protein-Coupled Receptor Kinase 5
Concept Phospholipase C beta
Concept AMP-Activated Protein Kinases
Concept Endosomal Sorting Complexes Required for Transport
Concept HEK293 Cells
Concept Receptors, Purinergic P2Y1
Concept Receptors, Purinergic P2Y12
Academic Article Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.
Academic Article Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function.
Academic Article Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity.
Academic Article Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3.
Academic Article Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but ß-arrestin-independent pathways.
Academic Article Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.
Academic Article G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.
Academic Article Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth.
Academic Article G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression.
Academic Article Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in vivo.
Academic Article G protein-coupled receptor kinase 5 phosphorylates nucleophosmin and regulates cell sensitivity to polo-like kinase 1 inhibition.
Academic Article Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic Acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.
Academic Article Identification of phosphorylation sites in the COOH-terminal tail of the µ-opioid receptor.
Academic Article G-protein-coupled receptors signal victory.
Academic Article ß-Arrestins and G Protein-Coupled Receptor Trafficking.
Academic Article G protein-coupled receptor kinase 2 (GRK2) is localized to centrosomes and mediates epidermal growth factor-promoted centrosomal separation.
Academic Article Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
Academic Article Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis.
Academic Article Regulation of arrestin-3 phosphorylation by casein kinase II.
Academic Article Biological actions of formoterol isomers.
Academic Article Novel beta2-adrenergic receptor signaling pathways.
Academic Article The ins and outs of G protein-coupled receptor trafficking.
Academic Article Differential interaction of GRK2 with members of the G alpha q family.
Academic Article Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation.
Academic Article Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins.
Academic Article G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation.
Academic Article The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4.
Academic Article Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin.
Academic Article A predicted amphipathic helix mediates plasma membrane localization of GRK5.
Academic Article Ubiquitination of G-protein-coupled receptors.
Academic Article Characterization of the GRK2 binding site of Galphaq.
Academic Article Analysis of G-protein-coupled receptor kinase RGS homology domains.
Academic Article A new key in breast cancer metastasis.
Academic Article Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2.
Academic Article Arrestin2 expression selectively increases during neural differentiation.
Academic Article Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling.
Academic Article Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2.
Academic Article P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.
Academic Article Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3.
Academic Article The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.
Academic Article Distinct clathrin-coated pits sort different G protein-coupled receptor cargo.
Academic Article Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages.
Academic Article Regulation of receptor trafficking by GRKs and arrestins.
Academic Article Regulation of CXCR4 signaling.
Academic Article Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A.
Academic Article Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.
Academic Article Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.
Academic Article Regulation of heterotrimeric G protein signaling in airway smooth muscle.
Academic Article Haloperidol and clozapine differentially affect the expression of arrestins, receptor kinases, and extracellular signal-regulated kinase activation.
Academic Article M3 muscarinic acetylcholine receptor-mediated signaling is regulated by distinct mechanisms.
Academic Article beta-Arrestin1 interacts with the G-protein subunits beta1gamma2 and promotes beta1gamma2-dependent Akt signalling for NF-kappaB activation.
Academic Article Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori.
Academic Article Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer.
Academic Article Arrestin2/clathrin interaction is regulated by key N- and C-terminal regions in arrestin2.
Academic Article Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
Academic Article Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking.
Academic Article Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation.
Academic Article G-protein-coupled-receptor kinases mediate TNFa-induced NF?B signalling via direct interaction with and phosphorylation of I?Ba.
Academic Article ß-Arrestins and G Protein-Coupled Receptor Trafficking.
Academic Article Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein.
Academic Article Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors.
Academic Article Role of ß-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking.
Academic Article Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization.
Academic Article Consequence of the tumor-associated conversion to cyclin D1b.
Academic Article Structural biology: Arresting developments in receptor signalling.
Academic Article Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases.
Academic Article Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms.
Academic Article From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins.
Academic Article The a-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the ß2-Adrenergic Receptor.
Academic Article ß-arrestin-biased signaling through the ß2-adrenergic receptor promotes cardiomyocyte contraction.
Academic Article c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes.
Grant Training Program in Cellular, Biochemical, and Molecular Sciences
Grant Role of Arrestins in G Protein-Coupled Receptor Regulation
Grant ARRESTINS IN G PROTEIN-COUPLE RECEPTOR REGULATION
Grant BETA-ADRENERGIC RECEPTOR REGULATION IN AIRWAY EPITHELIUM
Grant Training Program in Biomolecular Signal Transduction
Grant Arestin Interaction with Endocytic Components
Grant G Protein-Coupled Receptor Kinases
Grant Regulation of CXCR4 Signaling
Academic Article Structural and Functional Analysis of a ß2-Adrenergic Receptor Complex with GRK5.
Academic Article G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of ß-Arrestin.
Academic Article G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans.
Grant Characterization of beta-arrestin-biased beta 2-adrenergic receptor signaling in cardiovascular function
Grant Regulation of G protein-coupled receptor signaling and trafficking
Academic Article Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.
Academic Article G protein-coupled receptor kinases: Past, present and future.
Grant Structural and dynamic analysis of GRK interaction with G protein-coupled receptors
Academic Article Pepducins as a potential treatment strategy for asthma and COPD.
Academic Article Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.
Academic Article Pepducin-mediated cardioprotection via ß-arrestin-biased ß2-adrenergic receptor-specific signaling.
Academic Article G protein-coupled receptor kinase 5 modifies cancer cell resistance to paclitaxel.
Concept beta-Arrestin 1
Concept beta-Arrestins
Academic Article Biased agonism at ß-adrenergic receptors.
Academic Article Historical Perspective of the G Protein-Coupled Receptor Kinase Family.
Academic Article Targeting G protein-coupled receptor kinases (GRKs) to G protein-coupled receptors.
Academic Article Phenylalanine 193 in Extracellular Loop 2 of the ß2-Adrenergic Receptor Coordinates ß-Arrestin Interaction.
Academic Article Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4.
Academic Article Pepducin ICL1-9-Mediated ß2-Adrenergic Receptor-Dependent Cardiomyocyte Contractility Occurs in a Gi Protein/ROCK/PKD-Sensitive Manner.
Academic Article ß-agonist profiling reveals biased signalling phenotypes for the ß2 -adrenergic receptor with possible implications for the treatment of asthma.
Academic Article G protein-coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin.
Academic Article Identification of a ?-arrestin-biased negative allosteric modulator for the ?2-adrenergic receptor.
Search Criteria
  • Receptor
  • ErbB
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