Item Type | Name |
Concept
|
Actins
|
Concept
|
Adrenergic beta-Agonists
|
Concept
|
Adrenergic beta-Antagonists
|
Concept
|
Amino Acid Sequence
|
Concept
|
Animals
|
Concept
|
Antibodies
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Epitopes
|
Concept
|
Asthma
|
Concept
|
Base Sequence
|
Concept
|
Binding Sites
|
Concept
|
Blood Glucose
|
Concept
|
Brain Neoplasms
|
Concept
|
Breast Neoplasms
|
Concept
|
Calcium
|
Concept
|
Camelids, New World
|
Concept
|
Cattle
|
Concept
|
Cell Division
|
Concept
|
Cell Movement
|
Concept
|
Cercopithecus aethiops
|
Concept
|
Chemoreceptor Cells
|
Concept
|
Chemotaxis
|
Concept
|
Clathrin
|
Concept
|
Cysteine Endopeptidases
|
Concept
|
Diacetyl
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Drosophila
|
Concept
|
Enzyme Stability
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Glioblastoma
|
Concept
|
Glucocorticoids
|
Concept
|
Glutathione Transferase
|
Concept
|
Guanosine Triphosphate
|
Concept
|
Guinea Pigs
|
Concept
|
Haloperidol
|
Concept
|
Cricetinae
|
Concept
|
Humans
|
Concept
|
Immune Sera
|
Concept
|
Immunohistochemistry
|
Concept
|
Inositol
|
Concept
|
Inositol Phosphates
|
Concept
|
Insect Hormones
|
Concept
|
Insulin
|
Concept
|
Levodopa
|
Concept
|
Lipopolysaccharides
|
Concept
|
Longevity
|
Concept
|
Lysine
|
Concept
|
Lysosomes
|
Concept
|
Macrophages
|
Concept
|
Magnesium
|
Concept
|
Mammals
|
Concept
|
Melanoma
|
Concept
|
Microscopy, Electron
|
Concept
|
Microscopy, Fluorescence
|
Concept
|
Models, Biological
|
Concept
|
Models, Chemical
|
Concept
|
Models, Genetic
|
Concept
|
Models, Molecular
|
Concept
|
Molecular Conformation
|
Concept
|
Multienzyme Complexes
|
Concept
|
Neoplasm Invasiveness
|
Concept
|
Neoplasm Metastasis
|
Concept
|
Neovascularization, Pathologic
|
Concept
|
Phenylalanine
|
Concept
|
Phosphatidylethanolamines
|
Concept
|
Phospholipids
|
Concept
|
Phytic Acid
|
Concept
|
Precipitin Tests
|
Concept
|
Proinsulin
|
Concept
|
Prostatic Neoplasms
|
Concept
|
Protein Conformation
|
Concept
|
Receptors, Adrenergic
|
Concept
|
Receptors, Adrenergic, beta
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Receptors, Histamine H1
|
Concept
|
Receptors, Nicotinic
|
Concept
|
Rhodopsin
|
Concept
|
RNA, Messenger
|
Concept
|
Serotonin
|
Concept
|
Bombyx
|
Concept
|
Spectrometry, Fluorescence
|
Concept
|
Tetradecanoylphorbol Acetate
|
Concept
|
Tryptophan
|
Concept
|
Tumor Necrosis Factor-alpha
|
Concept
|
Uveal Neoplasms
|
Concept
|
Immunoblotting
|
Concept
|
Blotting, Western
|
Concept
|
Dopamine Agents
|
Concept
|
Survival Rate
|
Concept
|
Survival Analysis
|
Concept
|
Polymerase Chain Reaction
|
Concept
|
G2 Phase
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Mutagenesis
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
Cryoultramicrotomy
|
Concept
|
Caenorhabditis elegans
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Point Mutation
|
Concept
|
Sequence Deletion
|
Concept
|
In Situ Hybridization
|
Concept
|
Prostate-Specific Antigen
|
Concept
|
Protein Structure, Secondary
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Receptors, Somatostatin
|
Concept
|
Receptor, IGF Type 1
|
Concept
|
DNA Primers
|
Concept
|
Leukotriene D4
|
Concept
|
Receptors, Glucagon
|
Concept
|
Receptors, Purinergic P2
|
Concept
|
DNA, Complementary
|
Concept
|
Receptors, Leukotriene
|
Concept
|
Receptors, Adrenergic, alpha-2
|
Concept
|
Receptors, Adrenergic, beta-2
|
Concept
|
Centrosome
|
Concept
|
Disease Progression
|
Concept
|
Dopamine Agonists
|
Concept
|
Microscopy, Confocal
|
Concept
|
Receptor, ErbB-2
|
Concept
|
Muscarinic Agonists
|
Concept
|
Muscarinic Antagonists
|
Concept
|
Oncogene Proteins v-erbB
|
Concept
|
HSP90 Heat-Shock Proteins
|
Concept
|
HL-60 Cells
|
Concept
|
Phosphotyrosine
|
Concept
|
Cell Lineage
|
Concept
|
GTP-Binding Protein alpha Subunits, Gi-Go
|
Concept
|
Arrestins
|
Concept
|
Arrestin
|
Concept
|
Insect Proteins
|
Concept
|
COS Cells
|
Concept
|
Receptors, CXCR4
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
Concept
|
Calcium Signaling
|
Concept
|
K562 Cells
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
Concept
|
Amino Acid Motifs
|
Concept
|
rac1 GTP-Binding Protein
|
Concept
|
EF Hand Motifs
|
Concept
|
Protein Structure, Quaternary
|
Concept
|
MAP Kinase Signaling System
|
Concept
|
Heterotrimeric GTP-Binding Proteins
|
Concept
|
Electrophoretic Mobility Shift Assay
|
Concept
|
Ubiquitin
|
Concept
|
Drosophila Proteins
|
Concept
|
Caenorhabditis elegans Proteins
|
Concept
|
Animals, Genetically Modified
|
Concept
|
Adaptor Protein Complex beta Subunits
|
Concept
|
Dynamins
|
Concept
|
RNA, Small Interfering
|
Concept
|
Intercellular Signaling Peptides and Proteins
|
Concept
|
Receptors, G-Protein-Coupled
|
Concept
|
Receptor, Muscarinic M2
|
Concept
|
Receptor, Muscarinic M3
|
Concept
|
GTP-Binding Protein alpha Subunits, Gq-G11
|
Concept
|
Receptors, Serotonin, 5-HT2
|
Concept
|
GTP-Binding Protein alpha Subunits
|
Concept
|
GTP-Binding Protein beta Subunits
|
Concept
|
GTP-Binding Protein gamma Subunits
|
Concept
|
Receptors, Serotonin, 5-HT4
|
Concept
|
Antibodies, Phospho-Specific
|
Concept
|
Multiprotein Complexes
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
Lactams, Macrocyclic
|
Concept
|
Embryonic Development
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
Concept
|
Receptors, Lysophospholipid
|
Concept
|
Receptors, Lysosphingolipid
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
PTEN Phosphohydrolase
|
Concept
|
Mice
|
Concept
|
Rats
|
Concept
|
Proto-Oncogene Proteins c-mdm2
|
Concept
|
Tandem Mass Spectrometry
|
Concept
|
Phospholipase C beta
|
Concept
|
Genome-Wide Association Study
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Molecular Dynamics Simulation
|
Concept
|
Endosomal Sorting Complexes Required for Transport
|
Concept
|
Receptors, Purinergic P2Y1
|
Concept
|
Receptors, Purinergic P2Y12
|
Concept
|
Insulins
|
Academic Article
|
Bombyx adipokinetic hormone receptor activates extracellular signal-regulated kinase 1 and 2 via G protein-dependent PKA and PKC but ß-arrestin-independent pathways.
|
Academic Article
|
G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.
|
Academic Article
|
G-protein-coupled receptors signal victory.
|
Academic Article
|
ß-Arrestins and G Protein-Coupled Receptor Trafficking.
|
Academic Article
|
Fluorescence microscopy techniques for the study of G protein-coupled receptor trafficking.
|
Academic Article
|
Characterization of G protein-coupled receptor kinases.
|
Academic Article
|
Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
|
Academic Article
|
The third intracellular loop of alpha 2-adrenergic receptors determines subtype specificity of arrestin interaction.
|
Academic Article
|
G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation.
|
Academic Article
|
Characterization of the GRK2 binding site of Galphaq.
|
Academic Article
|
Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.
|
Academic Article
|
Regulation of heterotrimeric G protein signaling in airway smooth muscle.
|
Academic Article
|
Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori.
|
Academic Article
|
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
|
Academic Article
|
Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein.
|
Academic Article
|
Call for Papers! A Special Thematic Compilation/Special Issue Crossover with ACS Chemical Biology, ACS Medicinal Chemistry Letters, and the Journal of Medicinal Chemistry Focused on New Frontiers in Kinases.
|
Academic Article
|
Development and Characterization of Pepducins as Gs-biased Allosteric Agonists.
|
Academic Article
|
New frontiers in kinases.
|
Academic Article
|
Structural biology: Arresting developments in receptor signalling.
|
Academic Article
|
From biased signalling to polypharmacology: unlocking unique intracellular signalling using pepducins.
|
Grant
|
G Protein-Coupled Receptor Kinases
|
Academic Article
|
G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of ß-Arrestin.
|
Academic Article
|
G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans.
|
Academic Article
|
Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma.
|
Academic Article
|
Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.
|
Concept
|
beta-Arrestin 1
|
Concept
|
beta-Arrestins
|
Academic Article
|
PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells.
|