Thomas Jefferson University

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Brody, Jonathan
One or more keywords matched the following items that are connected to Brody, Jonathan
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Concept Pancreatic Neoplasms
Academic Article Identifying pancreatic cancer patients for targeted treatment: the challenges and limitations of the current selection process and vision for the future.
Academic Article Implications of enhancer of zeste homologue 2 expression in pancreatic ductal adenocarcinoma.
Academic Article HuR status is a powerful marker for prognosis and response to gemcitabine-based chemotherapy for resected pancreatic ductal adenocarcinoma patients.
Academic Article pp32 (ANP32A) expression inhibits pancreatic cancer cell growth and induces gemcitabine resistance by disrupting HuR binding to mRNAs.
Academic Article Subject review: pancreatic ductal adenocarcinoma in the setting of mutations in the cystic fibrosis transmembrane conductance regulator gene: case report and review of the literature.
Academic Article The past, present, and future of biomarkers: a need for molecular beacons for the clinical management of pancreatic cancer.
Academic Article HuR's role in gemcitabine efficacy: an exception or opportunity?
Academic Article Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma.
Academic Article Molecular profiling of synchronous and metachronous cancers of the pancreas reveal molecular mimicry between samples from the same patient.
Academic Article Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?
Academic Article Diagnostic, prognostic, and predictive biomarkers in pancreatic cancer.
Academic Article HuR's post-transcriptional regulation of Death Receptor 5 in pancreatic cancer cells.
Academic Article A novel survival-based tissue microarray of pancreatic cancer validates MUC1 and mesothelin as biomarkers.
Academic Article Molecular-based and alternative therapies for pancreatic cancer: looking "out of the box".
Academic Article Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer.
Academic Article Mitoxantrone Targets Human Ubiquitin-Specific Peptidase 11 (USP11) and Is a Potent Inhibitor of Pancreatic Cancer Cell Survival.
Academic Article Functional screen of the fanconi anemia pathway in cancer cells by Fancd2 immunoblot.
Academic Article Functional defects in the fanconi anemia pathway in pancreatic cancer cells.
Academic Article In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.
Academic Article Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers.
Academic Article Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy.
Academic Article Reduction of pp32 expression in poorly differentiated pancreatic ductal adenocarcinomas and intraductal papillary mucinous neoplasms with moderate dysplasia.
Academic Article High cancer-specific expression of mesothelin (MSLN) is attributable to an upstream enhancer containing a transcription enhancer factor dependent MCAT motif.
Academic Article Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection.
Academic Article Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome.
Academic Article Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells.
Academic Article Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma.
Academic Article Assessment of "gene-environment" interaction in cases of familial and sporadic pancreatic cancer.
Academic Article Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target.
Academic Article The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase.
Academic Article Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway.
Academic Article HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer.
Academic Article HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells.
Academic Article dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: A dual-institutional follow-up with the RTOG 9704 trial.
Academic Article MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer.
Academic Article Novel targets in pancreatic cancer research.
Academic Article Selective impact of CDK4/6 suppression on patient-derived models of pancreatic cancer.
Academic Article The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms.
Academic Article Personalized therapy for pancreatic cancer: Do we need better targets, arrows, or both?
Academic Article HuR Contributes to TRAIL Resistance by Restricting Death Receptor 4 Expression in Pancreatic Cancer Cells.
Academic Article WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner.
Academic Article Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer: A Post-hoc Analysis From the International Phase III ESPAC-3 Clinical Trial.
Academic Article Therapeutic Implications of Molecular Subtyping for Pancreatic Cancer.
Academic Article Identification of a novel metabolic-related mutation (IDH1) in metastatic pancreatic cancer.
Academic Article BRCA2 secondary mutation-mediated resistance to platinum and PARP inhibitor-based therapy in pancreatic cancer.
Academic Article Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells.
Academic Article A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative.
Academic Article Complex HuR function in pancreatic cancer cells.
Academic Article A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss-of-Function Polymorphisms in Indoleamine-2,3-Dioxygenase-2.
Academic Article Molecular Profiling of Pancreatic Cancer Patients: Initial Results from the Know Your Tumor Initiative.
Academic Article Organoid profiling identifies common responders to chemotherapy in pancreatic cancer.
Academic Article Host IDO2 gene status influences tumor progression and radiotherapy response in KRAS-driven sporadic pancreatic cancers.
Academic Article Evaluation of Post-transcriptional Gene Regulation in Pancreatic Cancer Cells: Studying RNA Binding Proteins and Their mRNA Targets.
Academic Article Metabolic Dependencies in Pancreatic Cancer.
Academic Article Genetic Drivers of Pancreatic Cancer Are Identical Between the Primary Tumor and a Secondary Lesion in a Long-Term (>5 Years) Survivor After a Whipple Procedure.
Academic Article Corrigendum: Metabolic Dependencies in Pancreatic Cancer.
Academic Article Abemaciclib Is Effective Against Pancreatic Cancer Cells and Synergizes with HuR and YAP1 Inhibition.
Academic Article Poly (ADP) ribose glycohydrolase can be effectively targeted in pancreatic cancer.
Academic Article Effect of Hypercapnia, an Element of Obstructive Respiratory Disorders, on Pancreatic Cancer Chemoresistance and Progression.
Academic Article Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial.
Academic Article A Phase I/II Study of Veliparib (ABT-888) in Combination with 5-Fluorouracil and Oxaliplatin in Patients with Metastatic Pancreatic Cancer.
Academic Article Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model.
Academic Article The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria.
Academic Article Gemcitabine-loaded microbubble system for ultrasound imaging and therapy.
Academic Article Disparities in pancreatic cancer care and research in Native Americans: Righting a history of wrongs.
Academic Article HuR Plays a Role in Double-Strand Break Repair in Pancreatic Cancer Cells and Regulates Functional BRCA1-Associated-Ring-Domain-1(BARD1) Isoforms.
Academic Article Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity.
Academic Article Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
Academic Article Repurposing the FDA-approved anthelmintic pyrvinium pamoate for pancreatic cancer treatment: study protocol for a phase I clinical trial in early-stage pancreatic ductal adenocarcinoma.
Academic Article Strategies for the Management of Patients with Pancreatic Cancer with PARP Inhibitors.
Academic Article Micelle-Formulated Juglone Effectively Targets Pancreatic Cancer and Remodels the Tumor Microenvironment.
Academic Article IDH1 inhibition potentiates chemotherapy efficacy in pancreatic cancer.
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