Item Type | Name |
Concept
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Adenoviridae
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Concept
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Adult
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Concept
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Aged
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Concept
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Aged, 80 and over
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Concept
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Animals
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Concept
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Base Sequence
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Concept
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Cell Adhesion
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Concept
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Cell Differentiation
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Concept
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Cell Division
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Concept
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Cell Line
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Concept
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Cell Movement
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Concept
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Cell Nucleus
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Concept
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Cell Survival
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Concept
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Cell Transformation, Neoplastic
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Concept
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Cells, Cultured
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Concept
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Enzyme-Linked Immunosorbent Assay
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Concept
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Epithelial Cells
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Concept
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Humans
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Concept
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Lactation
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Concept
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Lung Neoplasms
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Concept
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Lymphatic Metastasis
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Nude
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Concept
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Middle Aged
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Concept
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Neoplasm Recurrence, Local
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Concept
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Sheep
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Concept
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Tumor Cells, Cultured
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Concept
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Tumor Stem Cell Assay
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Concept
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Rats, Sprague-Dawley
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Concept
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Mice, Knockout
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Concept
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COS Cells
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Concept
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In Situ Nick-End Labeling
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Concept
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Active Transport, Cell Nucleus
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Concept
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Cell Line, Tumor
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Concept
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Mice
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Concept
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Rats
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Concept
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Young Adult
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Concept
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Programmed Cell Death 1 Receptor
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Academic Article
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Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth.
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Academic Article
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Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.
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Academic Article
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N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.
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Academic Article
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Activating mutation (V617F) in the tyrosine kinase JAK2 is absent in locally-confined or castration-resistant prostate cancer.
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Academic Article
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Targeting transcription factor Stat5a/b as a therapeutic strategy for prostate cancer.
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Academic Article
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Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure.
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Academic Article
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Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.
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Academic Article
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Signal transducer and activator of transcription-3 and breast cancer prognosis.
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Academic Article
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ROBUST GENE NETWORK ANALYSIS REVEALS ALTERATION OF THE STAT5a NETWORK AS A HALLMARK OF PROSTATE CANCER.
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Academic Article
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Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity.
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Academic Article
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Nuclear Stat5a/b predicts early recurrence and prostate cancer-specific death in patients treated by radical prostatectomy.
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Academic Article
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STAT5A/B Gene Locus Undergoes Amplification during Human Prostate Cancer Progression.
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Academic Article
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PRL signal transduction in the epithelial compartment of rat prostate maintained as long-term organ cultures in vitro.
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Academic Article
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Role of tyrosine kinase Jak2 in prolactin-induced differentiation and growth of mammary epithelial cells.
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Academic Article
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Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium.
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Academic Article
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Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells.
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Academic Article
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Activation of signal transducer and activator of transcription 5 in human prostate cancer is associated with high histological grade.
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Academic Article
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Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells.
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Academic Article
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Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.
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Academic Article
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The functional significance of nuclear receptor acetylation.
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Academic Article
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Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway.
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Academic Article
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Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells.
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Academic Article
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Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo.
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Academic Article
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Stat3 promotes metastatic progression of prostate cancer.
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Academic Article
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Androgen-regulated and highly tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor.
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Academic Article
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Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.
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Academic Article
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Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer.
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Academic Article
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Pharmacologic Suppression of JAK1/2 by JAK1/2 Inhibitor AZD1480 Potently Inhibits IL-6-Induced Experimental Prostate Cancer Metastases Formation.
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Academic Article
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Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.
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Academic Article
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Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
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Academic Article
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Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer.
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Academic Article
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Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland.
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Grant
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Stat5 in Progression of Prostate Cancer
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Grant
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Novel Strategy to Sensitize Prostate Cancer Cells to Radiation
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Academic Article
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Exosome-mediated Transfer of avß3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype.
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Academic Article
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miR-375 induces docetaxel resistance in prostate cancer by targeting SEC23A and YAP1.
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Academic Article
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Optimized b-value selection for the discrimination of prostate cancer grades, including the cribriform pattern, using diffusion weighted imaging.
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Academic Article
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Radio-pathomic Maps of Epithelium and Lumen Density Predict the Location of High-Grade Prostate Cancer.
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Academic Article
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Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia.
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Academic Article
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Targeting the STAT5 pathway in Ph+ acute lymphoblastic leukemia.
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Academic Article
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Gleason Probability Maps: A Radiomics Tool for Mapping Prostate Cancer Likelihood in MRI Space.
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Academic Article
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Positive STAT5 protein and locus amplification status predicts recurrence after radical prostatectomy to assist clinical precision management of prostate cancer.
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Academic Article
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Enzalutamide Induced Feed-Forward Signaling Loop Promotes Therapy-Resistant Prostate Cancer Growth Providing an Exploitable Molecular Target for Jak2 Inhibitors.
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Academic Article
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CYTOKINES, JAK-STAT SIGNALING AND RADIATION-INDUCED DNA REPAIR IN SOLID TUMORS: NOVEL OPPORTUNITIES FOR RADIATION THERAPY.
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Academic Article
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Prospects for Clinical Development of Stat5 Inhibitor IST5-002: High Transcriptomic Specificity in Prostate Cancer and Low Toxicity In Vivo.
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Academic Article
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Accurate segmentation of prostate cancer histomorphometric features using a weakly supervised convolutional neural network.
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Academic Article
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NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers.
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Academic Article
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Second-Generation Jak2 Inhibitors for Advanced Prostate Cancer: Are We Ready for Clinical Development?
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Academic Article
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Multi-Site Concordance of Diffusion-Weighted Imaging Quantification for Assessing Prostate Cancer Aggressiveness.
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Academic Article
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Spatial Metrics of Interaction between CD163-Positive Macrophages and Cancer Cells and Progression-Free Survival in Chemo-Treated Breast Cancer.
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Academic Article
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High PD-L2 Predicts Early Recurrence of ER-Positive Breast Cancer.
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Academic Article
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Stat5 induces androgen receptor (AR) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling.
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Academic Article
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Changes in Daily Apparent Diffusion Coefficient on Fully Quantitative Magnetic Resonance Imaging Correlate With Established Genomic Pathways of Radiation Sensitivity and Reveal Novel Biologic Associations.
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Academic Article
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Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer.
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Academic Article
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Prolactin is a survival factor for androgen-deprived rat dorsal and lateral prostate epithelium in organ culture.
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Academic Article
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One-step sample preparation of positive blood cultures for the direct detection of methicillin-sensitive and -resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci within one hour using the automated GenomEra CDX? PCR system.
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Academic Article
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Hormone regulation of human prostate in organ culture.
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Academic Article
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Inhalation of organic dusts and lipopolysaccharide increases gelatinolytic matrix metalloproteinases (MMPs) in the lungs of heaves horses.
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Academic Article
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Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression.
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Academic Article
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Expression and hormone regulation of prolactin receptors in rat dorsal and lateral prostate.
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Academic Article
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In vivo response-based identification of direct hormone target cell populations using high-density tissue arrays.
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Academic Article
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Estrogen and prolactin regulation of rat dorsal and lateral prostate in organ culture.
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Academic Article
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Epithelial defect in prostates of Stat5a-null mice.
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