Thomas Jefferson University

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Risbud, Makarand
One or more keywords matched the following items that are connected to Risbud, Makarand
Item TypeName
Concept Animals
Concept Animals, Newborn
Concept Disease Models, Animal
Concept Models, Animal
Academic Article Hypoxic regulation of nucleus pulposus cell survival: from niche to notch.
Academic Article Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling.
Academic Article Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc.
Academic Article Transcriptional profiling of the nucleus pulposus: say yes to notochord.
Academic Article Enhancement of intervertebral disc cell senescence by WNT/ß-catenin signaling-induced matrix metalloproteinase expression.
Academic Article Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord.
Academic Article Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease.
Academic Article Hypoxic regulation of ß-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins.
Academic Article TNF-a and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.
Academic Article Notochordal cells in the adult intervertebral disc: new perspective on an old question.
Academic Article HIF-1a and HIF-2a degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc.
Academic Article Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1a degradation.
Academic Article Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1a activity in hypoxia.
Academic Article Immunocytochemical localization of growth hormone-releasing hormone-like peptide in the brain of the tiger frog, Rana tigrina.
Academic Article Nonporous polyurethane membranes as islet immunoisolation matrices--biocompatibility studies.
Academic Article Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2.
Academic Article Models of pancreatic regeneration in diabetes.
Academic Article Radio-frequency plasma treatment improves the growth and attachment of endothelial cells on poly(methyl methacrylate) substrates: implications in tissue engineering.
Academic Article In vivo biocompatibility evaluation of cellulose macrocapsules for islet immunoisolation: Implications of low molecular weight cut-off.
Academic Article Hydrogel-coated textile scaffolds as candidate in liver tissue engineering: II. Evaluation of spheroid formation and viability of hepatocytes.
Academic Article An organ culture system for the study of the nucleus pulposus: description of the system and evaluation of the cells.
Academic Article Current strategies for cell delivery in cartilage and bone regeneration.
Academic Article Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy.
Academic Article Modeling of phosphate ion transfer to the surface of osteoblasts under normal gravity and simulated microgravity conditions.
Academic Article Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal.
Academic Article Chitosan: a versatile biopolymer for orthopaedic tissue-engineering.
Academic Article Cellular therapy for disc degeneration.
Academic Article Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival.
Academic Article Cell-based therapy for disc repair.
Academic Article Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.
Academic Article Toward an optimum system for intervertebral disc organ culture: TGF-beta 3 enhances nucleus pulposus and anulus fibrosus survival and function through modulation of TGF-beta-R expression and ERK signaling.
Academic Article TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc.
Academic Article Galectin-3 expression in the intervertebral disc: a useful marker of the notochord phenotype?
Academic Article Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro: implications for cell-based transplantation therapy.
Academic Article MEK/ERK signaling controls osmoregulation of nucleus pulposus cells of the intervertebral disc by transactivation of TonEBP/OREBP.
Academic Article Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.
Academic Article HIF-1 alpha is a regulator of galectin-3 expression in the intervertebral disc.
Academic Article Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling.
Academic Article Evidence for skeletal progenitor cells in the degenerate human intervertebral disc.
Academic Article SMAD3 functions as a transcriptional repressor of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc.
Academic Article Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc.
Academic Article Osmolarity and intracellular calcium regulate aquaporin2 expression through TonEBP in nucleus pulposus cells of the intervertebral disc.
Academic Article Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc.
Academic Article PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.
Academic Article Reversine enhances generation of progenitor-like cells by dedifferentiation of annulus fibrosus cells.
Academic Article BMP-2 and TGF-beta stimulate expression of beta1,3-glucuronosyl transferase 1 (GlcAT-1) in nucleus pulposus cells through AP1, TonEBP, and Sp1: role of MAPKs.
Grant Regeneration of Nucleus Pulposus by Tissue Engineering
Academic Article TNF-a promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells.
Grant Targeting cell senescence in a novel model of spontaneous disc degeneration
Academic Article The role of HIF proteins in maintaining the metabolic health of the intervertebral disc.
Academic Article Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice.
Academic Article The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration.
Academic Article Conditional Deletion of HIF-2a in Mouse Nucleus Pulposus Reduces Fibrosis and Provides Mild and Transient Protection From Age-Dependent Structural Changes in Intervertebral Disc.
Academic Article Loss of function mutation in Ank causes aberrant mineralization and acquisition of osteoblast-like-phenotype by the cells of the intervertebral disc.
Academic Article A new perspective on intervertebral disc calcification-from bench to bedside.
Academic Article Sdc4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging mouse spine.
Academic Article Toward understanding the cellular control of vertebrate mineralization: The potential role of mitochondria.
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