Thomas Jefferson University

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Risbud, Makarand
One or more keywords matched the following items that are connected to Risbud, Makarand
Item TypeName
Concept Hypoxia
Concept Cell Hypoxia
Concept Hypoxia-Inducible Factor 1
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Academic Article Hypoxic regulation of nucleus pulposus cell survival: from niche to notch.
Academic Article Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc.
Academic Article Hypoxia activates the notch signaling pathway in cells of the intervertebral disc: implications in degenerative disc disease.
Academic Article Hypoxic regulation of ?-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins.
Academic Article Notochordal cells in the adult intervertebral disc: new perspective on an old question.
Academic Article HIF-1a and HIF-2a degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc.
Academic Article Tonicity enhancer binding protein (TonEBP) and hypoxia-inducible factor (HIF) coordinate heat shock protein 70 (Hsp70) expression in hypoxic nucleus pulposus cells: role of Hsp70 in HIF-1a degradation.
Academic Article Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1a activity in hypoxia.
Academic Article Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-a (TNF-a) on cells of the nucleus pulposus through co-activation of nuclear factor ?B (NF-?B)/p65 signaling.
Academic Article Hypoxia-inducible factor (HIF)-1a and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1a level and transcriptional activity.
Academic Article Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissues.
Academic Article Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2.
Academic Article Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy.
Academic Article Nucleus pulposus cells upregulate PI3K/Akt and MEK/ERK signaling pathways under hypoxic conditions and resist apoptosis induced by serum withdrawal.
Academic Article Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival.
Academic Article Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.
Academic Article Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro: implications for cell-based transplantation therapy.
Academic Article Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.
Academic Article HIF-1 alpha is a regulator of galectin-3 expression in the intervertebral disc.
Academic Article Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc.
Academic Article HIF-1-PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells.
Academic Article Loss of HIF-1a in the notochord results in cell death and complete disappearance of the nucleus pulposus.
Academic Article FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.
Academic Article Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting.
Academic Article Prolyl-4-hydroxylase domain protein 2 controls NF-?B/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
Academic Article Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: Novel HIF-1-mediated regulation of aquaporins in NP cells.
Academic Article Class I and IIa HDACs Mediate HIF-1a Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1a Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
Academic Article The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
Academic Article Circadian factors BMAL1 and RORa control HIF-1a transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health.
Academic Article Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling.
Academic Article PHD3 is a transcriptional coactivator of HIF-1a in nucleus pulposus cells independent of the PKM2-JMJD5 axis.
Academic Article Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death.
Academic Article Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells.
Academic Article RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1a signaling in nucleus pulposus cells.
Academic Article Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health.
Concept Hypoxia-Inducible Factor-Proline Dioxygenases
Academic Article Hypoxic Regulation of Mitochondrial Metabolism and Mitophagy in Nucleus Pulposus Cells Is Dependent on HIF-1a-BNIP3 Axis.
Academic Article Hypoxia and Hypoxia-Inducible Factor-1a Regulate Endoplasmic Reticulum Stress in Nucleus Pulposus Cells: Implications of Endoplasmic Reticulum Stress for Extracellular Matrix Secretion.
Academic Article The role of HIF proteins in maintaining the metabolic health of the intervertebral disc.
Academic Article The mitophagy receptor BNIP3 is critical for the regulation of metabolic homeostasis and mitochondrial function in the nucleus pulposus cells of the intervertebral disc.
Academic Article GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc.
Search Criteria
  • Hypoxia