Thomas Jefferson University

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Wedegaertner, Philip
One or more keywords matched the following items that are connected to Wedegaertner, Philip
Item TypeName
Concept Cytoskeletal Proteins
Concept DNA-Binding Proteins
Concept Luminescent Proteins
Concept Membrane Proteins
Concept Microfilament Proteins
Concept Nerve Tissue Proteins
Concept Nuclear Proteins
Concept Protein Binding
Concept Protein Conformation
Concept Protein Kinase C
Concept Protein Kinases
Concept Protein Processing, Post-Translational
Concept Protein-Tyrosine Kinases
Concept Proto-Oncogene Proteins
Concept Recombinant Fusion Proteins
Concept Recombinant Proteins
Concept Viral Proteins
Concept Tumor Suppressor Protein p53
Concept Protein-Serine-Threonine Kinases
Concept Protein Prenylation
Concept Protein Structure, Secondary
Concept Protein Structure, Tertiary
Concept Protein Folding
Concept Cyclic AMP-Dependent Protein Kinases
Concept GTP-Binding Proteins
Concept GTP-Binding Protein alpha Subunits, Gs
Concept GTP-Binding Protein alpha Subunits, Gi-Go
Concept Protein Isoforms
Concept RGS Proteins
Concept rho GTP-Binding Proteins
Concept rhoA GTP-Binding Protein
Concept Receptor Protein-Tyrosine Kinases
Concept Heterotrimeric GTP-Binding Proteins
Concept Protein Subunits
Concept Protein Transport
Concept Zebrafish Proteins
Concept Ribosomal Protein S6 Kinases, 70-kDa
Concept Receptors, G-Protein-Coupled
Concept GTP-Binding Protein alpha Subunits, Gq-G11
Concept GTP-Binding Protein alpha Subunits, G12-G13
Concept GTP-Binding Protein alpha Subunits
Concept GTP-Binding Protein beta Subunits
Concept GTP-Binding Protein gamma Subunits
Concept Mitogen-Activated Protein Kinase 9
Concept Green Fluorescent Proteins
Concept Mutant Proteins
Concept Synaptosomal-Associated Protein 25
Concept Proto-Oncogene Proteins c-akt
Concept Focal Adhesion Protein-Tyrosine Kinases
Concept GTP-Binding Protein alpha Subunit, Gi2
Concept G-Protein-Coupled Receptor Kinases
Concept G-Protein-Coupled Receptor Kinase 2
Concept G-Protein-Coupled Receptor Kinase 3
Concept G-Protein-Coupled Receptor Kinase 4
Concept G-Protein-Coupled Receptor Kinase 5
Academic Article An N-terminal polybasic motif of Gaq is required for signaling and influences membrane nanodomain distribution.
Academic Article Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits.
Academic Article Non-canonical signaling and localizations of heterotrimeric G proteins.
Academic Article G protein trafficking.
Academic Article Coexpression of both alpha and beta subunits is required for assembly of regulated casein kinase II.
Academic Article Characterization of subcellular localization and stability of a splice variant of G alpha i2.
Academic Article Activation-induced subcellular redistribution of G alpha(s) is dependent upon its unique N-terminus.
Academic Article G protein-coupled receptor Kinase 2/G alpha q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding G alpha subunits.
Academic Article Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF.
Academic Article Heterotrimer formation, together with isoprenylation, is required for plasma membrane targeting of Gbetagamma.
Academic Article Mutation of an N-terminal acidic-rich region of p115-RhoGEF dissociates alpha13 binding and alpha13-promoted plasma membrane recruitment.
Academic Article Differential interaction of GRK2 with members of the G alpha q family.
Academic Article Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton.
Academic Article A predicted amphipathic helix mediates plasma membrane localization of GRK5.
Academic Article Exocytic pathway-independent plasma membrane targeting of heterotrimeric G proteins.
Academic Article Characterization of the GRK2 binding site of Galphaq.
Academic Article Analysis of G-protein-coupled receptor kinase RGS homology domains.
Academic Article Palmitoylation and plasma membrane targeting of RGS7 are promoted by alpha o.
Academic Article Identification of a specific domain responsible for JNK2alpha2 autophosphorylation.
Academic Article Functional consequences of G alpha 13 mutations that disrupt interaction with p115RhoGEF.
Academic Article Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling.
Academic Article Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth.
Academic Article Lipid-protein interactions in GPCR-associated signaling.
Academic Article Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A.
Academic Article Assembly and trafficking of heterotrimeric G proteins.
Academic Article Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor.
Academic Article FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.
Academic Article N-terminal polybasic motifs are required for plasma membrane localization of Galpha(s) and Galpha(q).
Academic Article Differences in Galpha12- and Galpha13-mediated plasma membrane recruitment of p115-RhoGEF.
Academic Article The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.
Academic Article Selectivity of phospholipase C phosphorylation by the epidermal growth factor receptor, the insulin receptor, and their cytoplasmic domains.
Academic Article The regulator of G protein signaling (RGS) domain of G protein-coupled receptor kinase 5 (GRK5) regulates plasma membrane localization and function.
Academic Article Activation of the purified protein tyrosine kinase domain of the epidermal growth factor receptor.
Academic Article Activation and depalmitoylation of Gs alpha.
Academic Article Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha.
Academic Article Lipid modifications and membrane targeting of G alpha.
Academic Article Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.
Academic Article Interaction with Gbetagamma is required for membrane targeting and palmitoylation of Galpha(s) and Galpha(q).
Academic Article Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding.
Academic Article Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.
Academic Article Effect of carboxyl terminal truncation on the tyrosine kinase activity of the epidermal growth factor receptor.
Academic Article Reciprocal regulation of Gs alpha by palmitate and the beta gamma subunit.
Academic Article G protein ß? subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway.
Academic Article Inducible Inhibition of Gß? Reveals Localization-dependent Functions at the Plasma Membrane and Golgi.
Academic Article G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling.
Academic Article Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma.
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  • GTP Binding Proteins