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Pestell, Richard
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Item TypeName
Concept Acute-Phase Proteins
Concept Bacterial Proteins
Concept Calcium-Binding Proteins
Concept Carrier Proteins
Concept Chromosomal Proteins, Non-Histone
Concept Contractile Proteins
Concept Cytoskeletal Proteins
Concept DNA-Binding Proteins
Concept Eye Proteins
Concept Fungal Proteins
Concept Heat-Shock Proteins
Concept High Mobility Group Proteins
Concept Luminescent Proteins
Concept Protein-Lysine 6-Oxidase
Concept Membrane Proteins
Concept Microfilament Proteins
Concept Microtubule-Associated Proteins
Concept Milk Proteins
Concept Monosaccharide Transport Proteins
Concept Muscle Proteins
Concept Neoplasm Proteins
Concept Nerve Tissue Proteins
Concept Nuclear Proteins
Concept Oncogene Proteins, Viral
Concept Protein Binding
Concept Protein Conformation
Concept Protein Kinase C
Concept Protein Kinases
Concept Protein Methyltransferases
Concept Protein Precursors
Concept Protein Processing, Post-Translational
Concept Protein-Energy Malnutrition
Concept Protein-Tyrosine Kinases
Concept Proteins
Concept Proto-Oncogene Proteins
Concept Recombinant Fusion Proteins
Concept Recombinant Proteins
Concept Repressor Proteins
Concept Protein Biosynthesis
Concept Oncogene Proteins
Concept Viral Structural Proteins
Concept Retroviridae Proteins, Oncogenic
Concept Oncogene Protein pp60(v-src)
Concept Oncogene Protein p21(ras)
Concept Tumor Suppressor Protein p53
Concept Retinoblastoma Protein
Concept CDC2 Protein Kinase
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins p21(ras)
Concept Extracellular Matrix Proteins
Concept RNA-Binding Proteins
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins c-fos
Concept Protein-Serine-Threonine Kinases
Concept Cyclic AMP Response Element-Binding Protein
Concept Protein Structure, Secondary
Concept Protein Structure, Tertiary
Concept Adenovirus E1A Proteins
Concept Cyclic AMP-Dependent Protein Kinases
Concept Calcium-Calmodulin-Dependent Protein Kinases
Concept Homeodomain Proteins
Concept ras Proteins
Concept Cell Cycle Proteins
Concept GTP-Binding Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept BRCA1 Protein
Concept Bone Morphogenetic Proteins
Concept Proto-Oncogene Proteins c-raf
Concept Mitogen-Activated Protein Kinase 1
Concept Protein Isoforms
Concept Monomeric GTP-Binding Proteins
Concept I-kappa B Proteins
Concept GTPase-Activating Proteins
Concept ral GTP-Binding Proteins
Concept rho GTP-Binding Proteins
Concept rhoA GTP-Binding Protein
Concept rac GTP-Binding Proteins
Concept cdc42 GTP-Binding Protein
Concept Receptor Protein-Tyrosine Kinases
Concept rac1 GTP-Binding Protein
Concept Mitogen-Activated Protein Kinases
Concept Mitogen-Activated Protein Kinase Kinases
Concept Protein Subunits
Concept Protein Transport
Concept CCAAT-Enhancer-Binding Proteins
Concept CCAAT-Enhancer-Binding Protein-alpha
Concept CCAAT-Enhancer-Binding Protein-beta
Concept Mitochondrial Proteins
Concept Tumor Suppressor Proteins
Concept Adenomatous Polyposis Coli Protein
Concept Tumor Suppressor Protein p14ARF
Concept SUMO-1 Protein
Concept Membrane Transport Proteins
Concept Cation Transport Proteins
Concept Saccharomyces cerevisiae Proteins
Concept Drosophila Proteins
Concept Zebrafish Proteins
Concept Intercellular Signaling Peptides and Proteins
Concept Silent Information Regulator Proteins, Saccharomyces cerevisiae
Concept Receptors, G-Protein-Coupled
Concept Parathyroid Hormone-Related Protein
Concept Ubiquitin-Protein Ligases
Concept Protein Kinase Inhibitors
Concept Intracellular Signaling Peptides and Proteins
Concept JNK Mitogen-Activated Protein Kinases
Concept p38 Mitogen-Activated Protein Kinases
Concept Mitogen-Activated Protein Kinase 3
Concept Adaptor Proteins, Signal Transducing
Concept Green Fluorescent Proteins
Concept Mutant Proteins
Concept Retinoblastoma-Like Protein p130
Concept Retinoblastoma-Like Protein p107
Concept Papillomavirus E7 Proteins
Concept Cyclin-Dependent Kinase Inhibitor Proteins
Concept Proto-Oncogene Proteins c-ets
Concept Proto-Oncogene Protein c-ets-2
Concept Suppressor of Cytokine Signaling Proteins
Concept E1A-Associated p300 Protein
Concept CREB-Binding Protein
Concept bcl-2 Homologous Antagonist-Killer Protein
Concept Apoptosis Regulatory Proteins
Concept bcl-Associated Death Protein
Concept Inhibitor of Apoptosis Proteins
Concept Proto-Oncogene Proteins c-akt
Concept Wnt Proteins
Concept Wnt1 Protein
Concept Glucose Transport Proteins, Facilitative
Concept Proto-Oncogene Proteins c-maf
Concept GRB7 Adaptor Protein
Concept Focal Adhesion Protein-Tyrosine Kinases
Concept Protein Kinase C-alpha
Concept Protein Kinase C-epsilon
Concept Protein Kinase C-delta
Concept Early Growth Response Protein 1
Concept Smad2 Protein
Concept Smad3 Protein
Concept Smad4 Protein
Concept Hedgehog Proteins
Concept Amyloid Precursor Protein Secretases
Concept Bone Morphogenetic Protein 4
Concept Retinoblastoma-Binding Protein 1
Concept Co-Repressor Proteins
Concept Transcription Factor 7-Like 2 Protein
Concept Zonula Occludens-1 Protein
Academic Article c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.
Academic Article Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells.
Academic Article Attenuation of Forkhead signaling by the retinal determination factor DACH1.
Academic Article Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model.
Academic Article microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling.
Academic Article ErbB2 induces Notch1 activity and function in breast cancer cells.
Academic Article Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors.
Academic Article CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway.
Academic Article Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment.
Academic Article HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis.
Academic Article C-jun inhibits mammary apoptosis in vivo.
Academic Article Cell fate determination factor Dachshund reprograms breast cancer stem cell function.
Academic Article Alternative cyclin D1 splice forms differentially regulate the DNA damage response.
Academic Article Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1.
Academic Article Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.
Academic Article The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
Academic Article Acetylation and nuclear receptor action.
Academic Article PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b.
Academic Article MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals.
Academic Article c-Jun is required for TGF-ß-mediated cellular migration via nuclear Ca²? signaling.
Academic Article The type 1 insulin-like growth factor receptor and resistance to DACH1.
Academic Article Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.
Academic Article Examining the role of cyclin D1 in breast cancer.
Academic Article Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.
Academic Article Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.
Academic Article SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA.
Academic Article Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
Academic Article Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration.
Academic Article Cyclin d1 induces chromosomal instability.
Academic Article Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.
Academic Article Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells.
Academic Article Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Academic Article p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
Academic Article Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.
Academic Article Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function.
Academic Article Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression.
Academic Article The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
Academic Article E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination.
Academic Article Interferon-beta activates multiple signaling cascades in primary human microglia.
Academic Article Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Academic Article Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.
Academic Article Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta.
Academic Article Senescence and epigenetic dysregulation in cancer.
Academic Article ErbB-2-induced mammary tumor growth: the role of cyclin D1 and p27Kip1.
Academic Article In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb.
Academic Article Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells.
Academic Article Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.
Academic Article Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
Academic Article Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways.
Academic Article Spatially discrete, light-driven protein expression.
Academic Article Role of BRCA1 in heat shock response.
Academic Article IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.
Academic Article Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1.
Academic Article Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.
Academic Article Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis.
Academic Article Gene expression phenotypic models that predict the activity of oncogenic pathways.
Academic Article Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells.
Academic Article BRCA1 gene in breast cancer.
Academic Article The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
Academic Article Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
Academic Article Trans-repression of beta-catenin activity by nuclear receptors.
Academic Article Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia.
Academic Article Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization.
Academic Article DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.
Academic Article p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.
Academic Article AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.
Academic Article Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth.
Academic Article BRCA1 inhibition of telomerase activity in cultured cells.
Academic Article Peroxisome proliferator-activated receptor gamma activation modulates cyclin D1 transcription via beta-catenin-independent and cAMP-response element-binding protein-dependent pathways in mouse hepatocytes.
Academic Article Histone acetylation/deacetylation as a regulator of cell cycle gene expression.
Academic Article Altered Rho GTPase signaling pathways in breast cancer cells.
Academic Article Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
Academic Article Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells.
Academic Article The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.
Academic Article Signal transduction mediated by cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential.
Academic Article Signal transduction inhibitors in cellular function.
Academic Article The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.
Academic Article Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice.
Academic Article Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.
Academic Article Bone morphogenetic protein signaling regulates postnatal hair follicle differentiation and cycling.
Academic Article Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.
Academic Article Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity.
Academic Article SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.
Academic Article Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection.
Academic Article Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells.
Academic Article Positherapy: targeted nuclear therapy of breast cancer with 18F-2-deoxy-2-fluoro-D-glucose.
Academic Article Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
Academic Article Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells.
Academic Article The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
Academic Article Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment.
Academic Article Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
Academic Article beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase.
Academic Article Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism.
Academic Article A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines.
Academic Article Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2.
Academic Article Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.
Academic Article 3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation.
Academic Article Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells.
Academic Article Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling.
Academic Article Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation.
Academic Article Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.
Academic Article Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
Academic Article Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA.
Academic Article Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3.
Academic Article Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells.
Academic Article Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.
Academic Article Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling.
Academic Article Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.
Academic Article Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.
Academic Article Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function.
Academic Article Hormonal control of androgen receptor function through SIRT1.
Academic Article DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.
Academic Article Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
Academic Article Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection.
Academic Article Cyclin D1 functions in cell migration.
Academic Article Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Academic Article Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Academic Article Epigenetics and the estrogen receptor.
Academic Article Akt1 governs breast cancer progression in vivo.
Academic Article Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells.
Academic Article Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1.
Academic Article High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
Academic Article Stabilization of SMAR1 mRNA by PGA2 involves a stem loop structure in the 5' UTR.
Academic Article DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells.
Academic Article Acetylation in nuclear receptor signaling and the role of sirtuins.
Academic Article Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migration.
Academic Article Inhibition of cyclin D1 gene transcription by Brg-1.
Academic Article Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB.
Academic Article Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Academic Article Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8.
Academic Article ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer.
Academic Article Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts.
Academic Article Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.
Academic Article Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism.
Academic Article MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.
Academic Article Cancer stem cells and the cell cycle: targeting the drive behind breast cancer.
Academic Article Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
Academic Article Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation.
Academic Article Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo.
Academic Article The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth.
Academic Article Altered expression of DACH1 and cyclin D1 in endometrial cancer.
Academic Article An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.
Academic Article PPARgamma activation induces autophagy in breast cancer cells.
Academic Article The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling.
Academic Article p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo.
Academic Article BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.
Academic Article The Dachshund gene in development and hormone-responsive tumorigenesis.
Academic Article Multiple promoter elements in the human chorionic gonadotropin beta subunit genes distinguish their expression from the luteinizing hormone beta gene.
Academic Article Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions.
Academic Article Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter.
Academic Article c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.
Academic Article Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C.
Academic Article Angiotensin II activation of cyclin D1-dependent kinase activity.
Academic Article Reduced cyclin D1 expression in the cerebella of nutritionally deprived rats correlates with developmental delay and decreased cellular DNA synthesis.
Academic Article Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways.
Academic Article A potential role for cell cycle control proteins in regulation of the cyclic adenosine 5'-monophosphate-responsive glycoprotein hormone alpha subunit gene.
Academic Article Induction of cyclin D1 by simian virus 40 small tumor antigen.
Academic Article Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways.
Academic Article Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2.
Academic Article Cyclin D1 is required for S phase traversal in bovine tracheal myocytes.
Academic Article Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo.
Academic Article Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.
Academic Article The effect of tumor necrosis factor-alpha and cAMP on induction of AP-1 activity in MA-10 tumor Leydig cells.
Academic Article Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1.
Academic Article Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in primary tracheal myocytes.
Academic Article Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun.
Academic Article Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer.
Academic Article Regulation of cyclin dependent kinase inhibitor proteins during neonatal cerebella development.
Academic Article Fos family members induce cell cycle entry by activating cyclin D1.
Academic Article Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade.
Academic Article Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.
Academic Article Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells.
Academic Article Identification of the cyclin D1 gene as a target of activating transcription factor 2 in chondrocytes.
Academic Article Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.
Academic Article pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells.
Academic Article BRCA1 inhibition of estrogen receptor signaling in transfected cells.
Academic Article Cell cycle genes in chondrocyte proliferation and differentiation.
Academic Article Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1).
Academic Article NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.
Academic Article Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells.
Academic Article Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA.
Academic Article Stat3 as an oncogene.
Academic Article Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway.
Academic Article p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.
Academic Article Caveolin-1 potentiates estrogen receptor alpha (ERalpha) signaling. caveolin-1 drives ligand-independent nuclear translocation and activation of ERalpha.
Academic Article Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.
Academic Article Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.
Academic Article Cell cycle regulation and RNA polymerase II.
Academic Article The cyclin D1 gene is transcriptionally repressed by caveolin-1.
Academic Article Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.
Academic Article Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression.
Academic Article Cell-cycle dysregulation and the molecular mechanisms of prostate cancer.
Academic Article Cell cycle molecules and diseases of the cardiovascular system.
Academic Article p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation.
Academic Article Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.
Academic Article The application of a lentiviral vector for gene transfer in fetal human hepatocytes.
Academic Article Gut-enriched Krüppel-like factor represses cyclin D1 promoter activity through Sp1 motif.
Academic Article The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
Academic Article Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype.
Academic Article The mammary gland iodide transporter is expressed during lactation and in breast cancer.
Academic Article Transforming growth factor-beta1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo.
Academic Article Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation.
Academic Article Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.
Academic Article Regulation of cyclin D(1) expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells.
Academic Article Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.
Academic Article Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.
Academic Article Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection.
Academic Article Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.
Academic Article Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.
Academic Article Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium.
Academic Article Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress.
Academic Article Caveolins in cholesterol trafficking and signal transduction: implications for human disease.
Academic Article Cell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycle.
Academic Article The application of high density microarray for analysis of mitogenic signaling and cell-cycle in the adrenal.
Academic Article Role of direct interaction in BRCA1 inhibition of estrogen receptor activity.
Academic Article Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism.
Academic Article Histone acetylation and the cell-cycle in cancer.
Academic Article Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.
Academic Article Bcl-2 induces cyclin D1 promoter activity in human breast epithelial cells independent of cell anchorage.
Academic Article Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner.
Academic Article Ras regulation of cyclin D1 promoter.
Academic Article Ras regulation of cyclin-dependent immunoprecipitation kinase assays.
Academic Article Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1.
Academic Article A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells.
Academic Article Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.
Academic Article Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding.
Academic Article Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras.
Academic Article Ligand-independent activation of oestrogen receptor alpha by caveolin-1.
Academic Article Prolactin negatively regulates caveolin-1 gene expression in the mammary gland during lactation, via a Ras-dependent mechanism.
Academic Article TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression.
Academic Article Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.
Academic Article Gastrin stabilises beta-catenin protein in mouse colorectal cancer cells.
Academic Article Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells.
Academic Article The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells.
Academic Article BCL-2 family protein, BAD is down-regulated in breast cancer and inhibits cell invasion.
Academic Article Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction.
Grant BREAST INDUCIBLE ANTISENSE CYCLIN D1 TRANSGENIC MICE
Grant Caveolin-1 and Cyclin D1 in Mammary Tumorigenesis
Grant REGULATION OF CYCLIN D1 EXPRESSION
Grant DACH1/Eya Cell fate determination factor and mammary tumorigenesis
Grant Impact of Cyclin D1 Isoforms in Breast Cancer
Grant Regulation of cyclin D1 Expression
Academic Article Recent advances of highly selective CDK4/6 inhibitors in breast cancer.
Academic Article The G protein coupled receptor CCR5 in cancer.
Grant CCR5 inhibitors to enhance therapeutic response of breast cancer to DNA damaging agents
Academic Article An Update on Glioblastoma Biology, Genetics, and Current Therapies: Novel Inhibitors of the G Protein-Coupled Receptor CCR5.
Academic Article Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis.
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