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Pestell, Richard
One or more keywords matched the following items that are connected to
Pestell, Richard
Item Type
Name
Concept
Oxidative Phosphorylation
Concept
Phosphorylation
Academic Article
Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model.
Academic Article
Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism.
Academic Article
Alternative cyclin D1 splice forms differentially regulate the DNA damage response.
Academic Article
Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo-Genomics.
Academic Article
Energy transfer in "parasitic" cancer metabolism: mitochondria are the powerhouse and Achilles' heel of tumor cells.
Academic Article
Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
Academic Article
Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.
Academic Article
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
Academic Article
Interferon-beta activates multiple signaling cascades in primary human microglia.
Academic Article
Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Academic Article
In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb.
Academic Article
Acetylation in hormone signaling and the cell cycle.
Academic Article
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.
Academic Article
Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis.
Academic Article
p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.
Academic Article
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.
Academic Article
Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity.
Academic Article
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
Academic Article
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
Academic Article
beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase.
Academic Article
Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2.
Academic Article
3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation.
Academic Article
Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation.
Academic Article
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.
Academic Article
Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.
Academic Article
Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1.
Academic Article
Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.
Academic Article
Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer.
Academic Article
Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells.
Academic Article
Transforming growth factor-beta1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo.
Academic Article
Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.
Academic Article
Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.
Academic Article
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.
Academic Article
Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress.
Academic Article
Caveolins in cholesterol trafficking and signal transduction: implications for human disease.
Academic Article
Ras regulation of cyclin-dependent immunoprecipitation kinase assays.
Academic Article
A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells.
Academic Article
Ligand-independent activation of oestrogen receptor alpha by caveolin-1.
Grant
Androgen Receptor Function in Prostate Cancer
Academic Article
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation.
Academic Article
Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation.
Search Criteria
Phosphorylation