Thomas Jefferson University

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Pestell, Richard
One or more keywords matched the following items that are connected to Pestell, Richard
Item TypeName
Concept Proto-Oncogene Proteins
Concept Proto-Oncogene Proteins c-myc
Concept Proto-Oncogene Proteins p21(ras)
Concept Proto-Oncogene Proteins c-jun
Concept Proto-Oncogene Proteins c-fos
Concept Proto-Oncogene Proteins c-bcl-2
Concept Proto-Oncogene Proteins c-raf
Concept Proto-Oncogene Proteins c-ets
Concept Proto-Oncogene Proteins c-akt
Concept Proto-Oncogene Proteins c-maf
Academic Article c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion.
Academic Article Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment.
Academic Article HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis.
Academic Article C-jun inhibits mammary apoptosis in vivo.
Academic Article Cell fate determination factor Dachshund reprograms breast cancer stem cell function.
Academic Article Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.
Academic Article Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Academic Article E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination.
Academic Article Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta.
Academic Article Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
Academic Article Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways.
Academic Article Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis.
Academic Article Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells.
Academic Article The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.
Academic Article Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection.
Academic Article Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells.
Academic Article Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.
Academic Article DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.
Academic Article Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Academic Article Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Academic Article Akt1 governs breast cancer progression in vivo.
Academic Article Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1.
Academic Article Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB.
Academic Article MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.
Academic Article An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.
Academic Article PPARgamma activation induces autophagy in breast cancer cells.
Academic Article p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo.
Academic Article BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha.
Academic Article Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions.
Academic Article Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter.
Academic Article c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.
Academic Article Angiotensin II activation of cyclin D1-dependent kinase activity.
Academic Article Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways.
Academic Article Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.
Academic Article The effect of tumor necrosis factor-alpha and cAMP on induction of AP-1 activity in MA-10 tumor Leydig cells.
Academic Article Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun.
Academic Article Fos family members induce cell cycle entry by activating cyclin D1.
Academic Article Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.
Academic Article Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.
Academic Article The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
Academic Article Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.
Academic Article Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.
Academic Article Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism.
Academic Article Bcl-2 induces cyclin D1 promoter activity in human breast epithelial cells independent of cell anchorage.
Academic Article Ras regulation of cyclin-dependent immunoprecipitation kinase assays.
Academic Article Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1.
Academic Article Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras.
Academic Article Regulation of ERa-dependent breast cancer metastasis by a miR-29a signaling.
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  • Proto Oncogene Proteins