Estradiol

"Estradiol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.

Descriptor ID	D004958
MeSH Number(s)	D04.210.500.365.415.248 D06.472.334.851.437.500
Concept/Terms	Estradiol Estradiol Estradiol-17 beta Estradiol 17 beta Estradiol Anhydrous Oestradiol Estradiol-17beta Estradiol 17beta 17 beta-Estradiol 17 beta Estradiol 17 beta-Oestradiol 17 beta Oestradiol Estradiol, (8 alpha,17 beta)-Isomer Estradiol, (8 alpha,17 beta)-Isomer Estradiol, Monosodium Salt Estradiol, Monosodium Salt Estradiol, Sodium Salt Estradiol, Sodium Salt Estradiol-17 alpha Estradiol-17 alpha Estradiol 17 alpha Estradiol, (17-alpha)-Isomer Ovocyclin Ovocyclin Vivelle Vivelle Aerodiol Aerodiol Estrace Estrace Estraderm TTS Estraderm TTS Estradiol Hemihydrate Estradiol Hemihydrate Estradiol Hemihydrate, (17 alpha)-Isomer Estradiol Hemihydrate, (17 alpha)-Isomer Estradiol Monohydrate Estradiol Monohydrate Estradiol, (+-)-Isomer Estradiol, (+-)-Isomer Estradiol, (-)-Isomer Estradiol, (-)-Isomer Estradiol, (16 alpha,17 alpha)-Isomer Estradiol, (16 alpha,17 alpha)-Isomer Estradiol, (16 alpha,17 beta)-Isomer Estradiol, (16 alpha,17 beta)-Isomer Estradiol, (8 alpha,17 beta)-(+-)-Isomer Estradiol, (8 alpha,17 beta)-(+-)-Isomer Estradiol, (9 beta,17 alpha)-Isomer Estradiol, (9 beta,17 alpha)-Isomer Estradiol, (9 beta,17 beta)-Isomer Estradiol, (9 beta,17 beta)-Isomer

Below are MeSH descriptors whose meaning is more general than "Estradiol".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Estranes [D04.210.500.365]
Estrenes [D04.210.500.365.415]
Estradiol [D04.210.500.365.415.248]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Gonadal Hormones [D06.472.334]
Gonadal Steroid Hormones [D06.472.334.851]
Estradiol Congeners [D06.472.334.851.437]
Estradiol [D06.472.334.851.437.500]

Below are MeSH descriptors whose meaning is related to "Estradiol".

Below are MeSH descriptors whose meaning is more specific than "Estradiol".

Estradiol
Estramustine

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Estradiol" by people in this website by year, and whether "Estradiol" was a major or minor topic of these publications.

Bar chart showing 167 publications over 30 distinct years, with a maximum of 14 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	2	5
1997	1	3	4
1998	2	3	5
1999	2	3	5
2000	4	1	5
2001	2	2	4
2002	4	3	7
2003	2	3	5
2004	2	0	2
2005	1	4	5
2006	6	5	11
2007	5	3	8
2008	6	8	14
2009	5	5	10
2010	1	4	5
2011	4	2	6
2012	1	5	6
2013	2	2	4
2014	2	5	7
2015	3	2	5
2016	6	3	9
2017	2	0	2
2018	3	4	7
2019	2	0	2
2020	3	3	6
2021	3	3	6
2022	1	1	2
2023	0	2	2
2024	2	3	5
2025	2	1	3

Below are the most recent publications written about "Estradiol" by people in Profiles.

Dillon GA, Harvey RE, Limberg JK, Nicholson WT, Joyner MJ, Baker SE, Miller VM, Ranadive SM. Acute exogenous oestradiol augments endothelial and smooth muscle vasodilatory responsiveness in premenopausal but not postmenopausal females. J Physiol. 2025 04; 603(8):2301-2311.

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Shenouda N, Stock JM, Chouramanis NV, Lincoln ZR, Wenner MM, Chirinos JA, Edwards DG. Favorable alterations in ventricular-arterial interactions across the menstrual cycle in healthy premenopausal women. Am J Physiol Heart Circ Physiol. 2025 03 01; 328(3):H648-H657.

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Nuckols VR, Shoemaker LN, Kuczmarski AV, Haigh KM, McGinty SJ, Del Vecchio AR, Schwab AI, Edwards DG, Taylor HS, Wenner MM. Short-term estradiol administration does not restore endothelin-B receptor-mediated vasodilation in postmenopausal women. Am J Physiol Heart Circ Physiol. 2025 02 01; 328(2):H327-H332.

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Ivanidze J, Sharbatdaran A, McCalla A, Brandmaier A, Andreopoulou E, Cristofanilli M, Cigler T, Balogun OD, Magge RS, Liechty B, Karakatsanis NA, Nehmeh SA, Agee MA, Jean J, Osborne JR, Beal K, Schwartz TH, Pannullo SC, Knisely JPS, Ramakrishna R. [18F]-Fluoroestradiol (FES) brain PET in the evaluation of patients with estrogen receptor positive breast cancer and known or suspected brain metastases. Eur J Radiol. 2024 Dec; 181:111791.

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Wenner MM, Shenouda N, Shoemaker L, Kuczmarski A, Haigh K, Del Vecchio A, Schwab A, McGinty SJ, Edwards DG, Pohlig RT, Nuckols VR, DuBose L, Moreau KL. Characterizing vascular and hormonal changes in women across the life span: a cross-sectional analysis. Am J Physiol Heart Circ Physiol. 2024 11 01; 327(5):H1286-H1295.

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Assayag E, Gurt I, Cohen-Kfir E, Stokar J, Zwas DR, Dresner-Pollak R. Cardiac Left Ventricular miRNA-26a Is Downregulated in Ovariectomized Mice, Upregulated upon 17-Beta Estradiol Replacement, and Inversely Correlated with Collagen Type 1 Gene Expression. Int J Mol Sci. 2024 May 09; 25(10).

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Lam K, Kraft WK, Zhan T, Lam E. Bidirectional pharmacokinetics of doravirine, tenofovir, and feminizing hormones in transgender women (IDentify): A randomized crossover trial. Clin Transl Sci. 2024 03; 17(3):e13721.

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Singh A, Tripathi R, Gupta RK, Rashid R, Jha RK. Gonadotropin upregulates intraovarian calpains-1 and -2 during ovarian follicular recruitment in the SD rat model. Reprod Biol. 2024 Jun; 24(2):100862.

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Huang SD, Bamba V, Bothwell S, Fechner PY, Furniss A, Ikomi C, Nahata L, Nokoff NJ, Pyle L, Seyoum H, Davis SM. Development and validation of a computable phenotype for Turner syndrome utilizing electronic health records from a national pediatric network. Am J Med Genet A. 2024 04; 194(4):e63495.

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Rutherford DV, Medley S, Henderson NC, Gersch CL, Vandenberg TA, Albain KS, Dakhil SR, Tirumali NR, Gralow JR, Hortobagyi GN, Pusztai L, Mehta RS, Hayes DF, Kidwell KM, Henry NL, Barlow WE, Rae JM, Hertz DL. Effects of CYP3A4 and CYP2C9 genotype on systemic anastrozole and fulvestrant concentrations in SWOG S0226. Pharmacogenomics. 2023 08; 24(12):665-673.

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