"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
| Descriptor ID |
D005109
|
| MeSH Number(s) |
A11.284.295.310
|
| Concept/Terms |
Extracellular Matrix- Extracellular Matrix
- Matrix, Extracellular
- Extracellular Matrices
- Matrices, Extracellular
|
Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".
This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 2 | 1 | 3 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 3 | 5 |
| 2003 | 2 | 9 | 11 |
| 2004 | 2 | 5 | 7 |
| 2005 | 2 | 6 | 8 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 4 | 5 |
| 2009 | 4 | 5 | 9 |
| 2010 | 2 | 5 | 7 |
| 2011 | 5 | 6 | 11 |
| 2012 | 7 | 4 | 11 |
| 2013 | 5 | 4 | 9 |
| 2014 | 6 | 4 | 10 |
| 2015 | 5 | 6 | 11 |
| 2016 | 4 | 4 | 8 |
| 2017 | 1 | 5 | 6 |
| 2018 | 5 | 5 | 10 |
| 2019 | 5 | 1 | 6 |
| 2020 | 3 | 4 | 7 |
| 2021 | 1 | 2 | 3 |
| 2022 | 2 | 0 | 2 |
| 2023 | 0 | 5 | 5 |
| 2024 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.
-
Gao H, Pol M, Makara CA, Song J, Zhang H, Zou X, Benson JM, Burris DL, Fox JM, Jia X. Bio-orthogonal tuning of matrix properties during 3D cell culture to induce morphological and phenotypic changes. Nat Protoc. 2025 03; 20(3):727-778.
-
Dogan E, Galifi CA, Cecen B, Shukla R, Wood TL, Miri AK. Extracellular matrix regulation of cell spheroid invasion in a 3D bioprinted solid tumor-on-a-chip. Acta Biomater. 2024 09 15; 186:156-166.
-
Pol M, Gao H, Zhang H, George OJ, Fox JM, Jia X. Dynamic modulation of matrix adhesiveness induces epithelial-to-mesenchymal transition in prostate cancer cells in 3D. Biomaterials. 2023 08; 299:122180.
-
Fertala J, Wang ML, Rivlin M, Beredjiklian PK, Abboud J, Arnold WV, Fertala A. Extracellular Targets to Reduce Excessive Scarring in Response to Tissue Injury. Biomolecules. 2023 04 27; 13(5).
-
Endzhievskaya S, Hsu CK, Yang HS, Huang HY, Lin YC, Hong YK, Lee JYW, Onoufriadis A, Takeichi T, Yu-Yun Lee J, Shaw TJ, McGrath JA, Parsons M. Loss of RhoE Function in Dermatofibroma Promotes Disorganized Dermal Fibroblast Extracellular Matrix and Increased Integrin Activation. J Invest Dermatol. 2023 08; 143(8):1487-1497.e9.
-
DeDreu J, Le PM, Menko AS. The ciliary zonules provide a pathway for immune cells to populate the avascular lens during eye development. Exp Biol Med (Maywood). 2022 12; 247(24):2251-2273.
-
Sperle K, Pochan DJ, Langhans SA. 3D Hydrogel Cultures for High-Throughput Drug Discovery. Methods Mol Biol. 2023; 2614:369-381.
-
Lee N, Shi L, Colon Caraballo M, Nallasamy S, Mahendroo M, Iozzo RV, Myers K. Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy. J Biomech Eng. 2022 06 01; 144(6).
-
Chen CG, Iozzo RV. Extracellular matrix guidance of autophagy: a mechanism regulating cancer growth. Open Biol. 2022 01; 12(1):210304.
-
Schaefer L, Dikic I. Autophagy: Instructions from the extracellular matrix. Matrix Biol. 2021 06; 100-101:1-8.