"Fumarate Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reversible hydration of fumaric acid to yield L-malic acid. It is one of the citric acid cycle enzymes. EC 4.2.1.2.
| Descriptor ID |
D005649
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| MeSH Number(s) |
D08.811.520.241.300.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fumarate Hydratase".
Below are MeSH descriptors whose meaning is more specific than "Fumarate Hydratase".
This graph shows the total number of publications written about "Fumarate Hydratase" by people in this website by year, and whether "Fumarate Hydratase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fumarate Hydratase" by people in Profiles.
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Miettinen M, Felisiak-Golabek A, Wasag B, Chmara M, Wang Z, Butzow R, Lasota J. Fumarase-deficient Uterine Leiomyomas: An Immunohistochemical, Molecular Genetic, and Clinicopathologic Study of 86 Cases. Am J Surg Pathol. 2016 12; 40(12):1661-1669.
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Wheeler KC, Warr DJ, Warsetsky SI, Barmat LI. Novel fumarate hydratase mutation in a family with atypical uterine leiomyomas and hereditary leiomyomatosis and renal cell cancer. Fertil Steril. 2016 Jan; 105(1):144-8.
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Gatalica Z, Lilleberg SL, Monzon FA, Koul MS, Bridge JA, Knezetic J, Legendre B, Sharma P, McCue PA. Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypes. Hum Pathol. 2011 Dec; 42(12):1979-88.
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Chan I, Wong T, Martinez-Mir A, Christiano AM, McGrath JA. Familial multiple cutaneous and uterine leiomyomas associated with papillary renal cell cancer. Clin Exp Dermatol. 2005 Jan; 30(1):75-8.
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Maianski NA, Geissler J, Srinivasula SM, Alnemri ES, Roos D, Kuijpers TW. Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis. Cell Death Differ. 2004 Feb; 11(2):143-53.
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McGrath JA. Biologic lessons from mutations in the Kreb's cycle enzyme, fumarate hydratase. J Invest Dermatol. 2003 Oct; 121(4):vii.